Orioles vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for April 7

Odds updated as of 2:12 p.m.

The Baltimore Orioles are among the MLB teams in action on Tuesday, up against the Chicago White Sox.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital info about this matchup.

Orioles vs White Sox Game Info

• Baltimore Orioles (4-6) vs. Chicago White Sox (4-6)
• Date: Tuesday, April 7, 2026
• Time: 3:10 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN+ and MASN

Orioles vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BAL: (-154) | CHW: (+130)
• Spread: BAL: -1.5 (+125) | CHW: +1.5 (-150)
• Total: 6.5 -- Over: (-122) | Under: (+100)

Orioles vs White Sox Probable Starting Pitchers

Probable Pitchers: Trevor Rogers (Orioles) - 2-0, 1.38 ERA vs Shane Smith (White Sox) - 0-2, 19.29 ERA

The Orioles will call on Trevor Rogers (2-0) versus the White Sox and Shane Smith (0-2). Rogers has a record of 1-1-0 ATS in two starts with a spread this season. Rogers' team is 2-0 this season when he starts and they're favored on the moneyline. Smith has started two games with set spreads, and the White Sox failed to cover in both opportunities. The White Sox were the underdog on the moneyline for two Smith starts this season -- they lost both.

Orioles vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Orioles win (50.6%)

Orioles vs White Sox Moneyline

• Looking at the moneyline for Orioles-White Sox, Baltimore is the favorite at -154, and Chicago is +130 playing at home.

Orioles vs White Sox Spread

• The Orioles are favored by 1.5 runs on the road against the White Sox. The Orioles are +125 to cover the spread, while the White Sox are -150.

Orioles vs White Sox Over/Under

• A combined run total of 6.5 has been set for Orioles-White Sox on April 7, with the over at -122 and the under at +100.

Bet on Baltimore Orioles vs. Chicago White Sox on FanDuel today!

Orioles vs White Sox Betting Trends

• The Orioles have been chosen as favorites in seven games this year and have walked away with the win four times (57.1%) in those games.
• Baltimore has been listed as a favorite of -154 or more on two occasions this season and split those games.
• Contests with the Orioles have gone over the total set by sportsbooks in five of 10 chances this season.
• The Orioles have posted a record of 2-8-0 against the spread this season.
• The White Sox have won 40% of the games this season they were the underdog on the moneyline (4-6).
• Chicago has a 2-3 record (winning 40% of its games) when it has played as a moneyline underdog of +130 or longer.
• The White Sox have combined with opponents to go over the total seven times this season for a 7-3-0 record against the over/under.
• The White Sox have a 5-5-0 record against the spread this season.

Orioles Player Leaders

• Gunnar Henderson leads Baltimore with nine hits, batting .220 this season with five extra-base hits. He has an on-base percentage of .304 and a slugging percentage of .488.
• He ranks 111th in batting average, 116th in on-base percentage, and 53rd in slugging among qualifying hitters in baseball.
• Taylor Ward leads the Orioles with an OPS of .875. He has a slash line of .333/.413/.462 this season.
• He is 22nd in batting average, 28th in on-base percentage and 64th in slugging in MLB.
• Ward enters this matchup looking to extend his two-game hit streak. In his last five games he is hitting .368 with four doubles, three walks and three RBIs.
• Adley Rutschman has seven hits this season and has a slash line of .292/.414/.458.
• Dylan Beavers has been key for Baltimore with eight hits, an OBP of .308 plus a slugging percentage of .462.
• Beavers brings a four-game hitting streak into this game. During his last five outings he is batting .350 with a home run and two RBIs.

White Sox Player Leaders

• Miguel Vargas has accumulated a .375 on-base percentage and a .500 slugging percentage, both team-high numbers for the White Sox. He's batting .250.
• Including all the qualifying hitters in MLB, he is 81st in batting average, 50th in on-base percentage and 50th in slugging percentage.
• Munetaka Murakami's seven hits lead his team. He has a batting average of .206 while slugging .559 with an on-base percentage of .333.
• His batting average ranks 129th among all qualified players, his on-base percentage ranks 83rd, and he is 29th in slugging.
• Chase Meidroth has racked up a team-best .394 slugging percentage.
• Colson Montgomery is hitting .200 with two home runs and four walks.

Orioles vs White Sox Head to Head

• 4/6/2026: 2-1 BAL (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 9/17/2025: 3-1 BAL (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 9/16/2025: 8-7 BAL (Favorite: White Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 9/15/2025: 4-1 BAL (Favorite: Orioles, Spread: -1.5, Total: 8, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 6/1/2025: 3-2 BAL (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 5/31/2025: 4-2 BAL (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 5/30/2025: 2-1 BAL (Favorite: Orioles, Spread: -1.5, Total: 9, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 9/4/2024: 8-1 CHW (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -375, Underdog Moneyline: +300)
• 9/3/2024: 9-0 BAL (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -320, Underdog Moneyline: +260)
• 9/2/2024: 13-3 BAL (Favorite: Orioles, Spread: -1.5, Total: 8, Favorite Moneyline: -460, Underdog Moneyline: +360)

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