Oregon vs Northwestern Prediction, Odds, Picks, Best Bets for Week 3 2025

On Saturday in college football, the Oregon Ducks are up against the Northwestern Wildcats.

Before you make your wager on FanDuel Sportsbook, we've got you covered, in terms of the vital info regarding today's NCAA football betting odds.

Oregon vs Northwestern Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Oregon: (-7692) | Northwestern: (+2200)
• Spread: Oregon: -27.5 (-105) | Northwestern: +27.5 (-115)
• Total: 48.5 -- Over: (-110) | Under: (-110)

Oregon vs Northwestern Betting Trends

• Oregon has won twice against the spread this year.
• Oregon has covered every time (2-0) as a 27.5-point favorite or greater this year.
• All two of Oregon's games have hit the over this season.
• Northwestern has one win against the spread this season.
• Northwestern and its opponent have yet to go over the total this season.

Oregon vs Northwestern Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Ducks win (93.8%)

Oregon vs Northwestern Point Spread

Oregon is favored by 27.5 points over Northwestern. Oregon is -105 to cover the spread, with Northwestern being -115.

Oregon vs Northwestern Over/Under

The Oregon-Northwestern matchup on Sept. 13 has been given an over/under of 48.5 points. The over is -110 and the under is -110.

Oregon vs Northwestern Moneyline

Looking at the moneyline for Northwestern-Oregon, Northwestern is the underdog at +2200, and Oregon is -7692.

Oregon vs. Northwestern Points Insights

Oregon vs. Northwestern Game Info

• Game day: Saturday, September 13, 2025
• Game time: 12 p.m. ET
• TV channel: FOX
• Location: Evanston, Illinois
• Stadium: Northwestern Medicine Field at Martin Stadium

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Check out even more in-depth Oregon vs. Northwestern analysis on FanDuel Research.