Old Dominion vs Liberty Prediction, Odds, Picks, Best Bets for Week 5 2025

In college football action on Saturday, the Old Dominion Monarchs face the Liberty Flames.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA football odds and spreads you need to know.

Old Dominion vs Liberty Odds & Spread

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Old Dominion: (-671) | Liberty: (+470)
• Spread: Old Dominion: -14.5 (-115) | Liberty: +14.5 (-105)
• Total: 54.5 -- Over: (-110) | Under: (-110)

Old Dominion vs Liberty Betting Trends

• Old Dominion's record against the spread is 3-0-0.
• Old Dominion is unbeaten ATS (1-0) as a 14.5-point favorite or greater this season.
• Old Dominion has had two games (out of three) go over the total this year.
• Liberty has not won a game against the spread this season.
• One Liberty game (out of four) has hit the over this season.

Old Dominion vs Liberty Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Monarchs win (81.3%)

Old Dominion vs Liberty Point Spread

Old Dominion is favored by 14.5 points against Liberty. Old Dominion is -115 to cover the spread, while Liberty is -105.

Old Dominion vs Liberty Over/Under

The Old Dominion-Liberty game on Sept. 27 has been given an over/under of 54.5 points. The over is -110 and the under is -110.

Old Dominion vs Liberty Moneyline

Old Dominion is the favorite, -671 on the moneyline, while Liberty is a +470 underdog.

Old Dominion vs. Liberty Points Insights

Old Dominion vs. Liberty Game Info

• Game day: Saturday, September 27, 2025
• Game time: 6 p.m. ET
• TV channel: ESPN+
• Location: Norfolk, Virginia
• Stadium: Kornblau Field at S.B. Ballard Stadium

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

Check out even more in-depth Old Dominion vs. Liberty analysis on FanDuel Research.