Oklahoma vs Michigan Prediction, Odds, Picks, Best Bets for Week 2 2025

On Saturday in college football, the Oklahoma Sooners are playing the Michigan Wolverines.

Before you make your wager on FanDuel Sportsbook, we've got you covered, in terms of the vital info regarding today's NCAA football betting odds.

Oklahoma vs Michigan Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Oklahoma: (-200) | Michigan: (+164)
• Spread: Oklahoma: -5.5 (-110) | Michigan: +5.5 (-110)
• Total: 43.5 -- Over: (-115) | Under: (-105)

Oklahoma vs Michigan Betting Trends

• Oklahoma has no wins against the spread this year.
• Oklahoma has yet to win ATS (0-1) when playing as at least 5.5-point favorites this year.
• Michigan has not won a game against the spread this year.
• Michigan has had one game (of one) go over the total this season.

Oklahoma vs Michigan Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Sooners win (58.9%)

Oklahoma vs Michigan Point Spread

Michigan is the underdog by 5.5 points against Oklahoma. Michigan is -110 to cover the spread, and Oklahoma is -110.

Oklahoma vs Michigan Over/Under

The Oklahoma-Michigan matchup on Sept. 6 has been given an over/under of 43.5 points. The over is -115 and the under is -105.

Oklahoma vs Michigan Moneyline

The moneyline numbers for Oklahoma vs. Michigan reveal Oklahoma as the favorite (-200) and Michigan as the underdog (+164).

Oklahoma vs. Michigan Points Insights

• The Sooners' average implied point total last season was 6.2 more points than their implied total in Saturday's game (31.2 implied points on average compared to 25 implied points in this game).
• The Wolverines' average implied point total last season (26.9 points) is 7.9 points higher than their implied total in this matchup (19 points).

Oklahoma vs. Michigan Game Info

• Game day: Saturday, September 6, 2025
• Game time: 7:30 p.m. ET
• TV channel: ABC
• Location: Norman, Oklahoma
• Stadium: Gaylord Family Oklahoma Memorial Stadium

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Check out even more in-depth Oklahoma vs. Michigan analysis on FanDuel Research.