North Carolina vs Charlotte Prediction, Odds, Picks, Best Bets for Week 2 2025

Saturday's slate in college football includes a matchup between the North Carolina Tar Heels and the Charlotte 49ers.

We've got you covered, in terms of the vital info regarding NCAA football betting lines, before you make your wager on FanDuel Sportsbook.

North Carolina vs Charlotte Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: North Carolina: (-549) | Charlotte: (+400)
• Spread: North Carolina: -13.5 (-110) | Charlotte: +13.5 (-110)
• Total: 49.5 -- Over: (-110) | Under: (-110)

North Carolina vs Charlotte Betting Trends

• North Carolina hasn't won a game against the spread this season.
• North Carolina has had one game (of one) go over the total this year.
• Charlotte has not won a game against the spread this year.
• None of Charlotte's one games has hit the over in 2025.

North Carolina vs Charlotte Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Tar Heels win (77.1%)

North Carolina vs Charlotte Point Spread

North Carolina is a 13.5-point favorite against Charlotte. North Carolina is -110 to cover the spread, and Charlotte is -110.

North Carolina vs Charlotte Over/Under

The North Carolina-Charlotte game on Sept. 6 has been given an over/under of 49.5 points. The over is -110 and the under is -110.

North Carolina vs Charlotte Moneyline

Charlotte is a +400 underdog on the moneyline, while North Carolina is a -549 favorite.

North Carolina vs. Charlotte Points Insights

• The average implied total for the Tar Heels last season was 31.5 points, 0.5 fewer points than their implied total of 32 points in Saturday's game.
• The 49ers' average implied point total last season (31.8 points) is 13.8 points higher than their implied total in this matchup (18 points).

North Carolina vs. Charlotte Game Info

• Game day: Saturday, September 6, 2025
• Game time: 7 p.m. ET
• TV channel: ESPN+
• Location: Charlotte, North Carolina
• Stadium: Jerry Richardson Stadium

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