Nationals vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for July 6

Odds updated as of 6:12 p.m.

The Washington Nationals are among the MLB squads busy on Monday, up against the Houston Astros.

All the information you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Nationals vs Astros Game Info

• Washington Nationals (46-45) vs. Houston Astros (45-47)
• Date: Monday, July 6, 2026
• Time: 6:45 p.m. ET
• Venue: Nationals Park -- Washington, District of Columbia
• Coverage: Nationals.TV and SCHN

Nationals vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: WSH: (-116) | HOU: (-102)
• Spread: WSH: +1.5 (-192) | HOU: -1.5 (+158)
• Total: 9.5 -- Over: (-122) | Under: (+100)

Nationals vs Astros Probable Starting Pitchers

Probable Pitchers: Miles Mikolas (Nationals) - 2-7, 5.44 ERA vs Mike Burrows (Astros) - 4-8, 5.58 ERA

The probable pitchers are Miles Mikolas (2-7) for the Nationals and Mike Burrows (4-8) for the Astros. When Mikolas starts, his team is 3-4-0 against the spread this season. Mikolas has yet to start a game this season when his team was the moneyline favorite. When Burrows starts, the Astros have gone 6-10-0 against the spread. The Astros are 6-5 in Burrows' 11 starts this season that they were the moneyline underdog.

Nationals vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Nationals win (51.7%)

Nationals vs Astros Moneyline

• Washington is the favorite, -116 on the moneyline, while Houston is a -102 underdog on the road.

Nationals vs Astros Spread

• The Astros are 1.5-run favorites against the spread for this matchup with the Nationals. The Astros are +158 to cover, while the Nationals are -192 to cover as a 1.5-run underdog on the runline.

Nationals vs Astros Over/Under

• A combined run total of 9.5 has been set for Nationals-Astros on July 6, with the over at -122 and the under at +100.

Bet on Washington Nationals vs. Houston Astros on FanDuel today!

Nationals vs Astros Betting Trends

• The Nationals have been chosen as favorites in 11 games this year and have walked away with the win five times (45.5%) in those games.
• This season Washington has come away with a win five times in 10 chances when named as a favorite of at least -116 on the moneyline.
• The Nationals and their opponents have gone over in 53 of their 89 games with a total set by sportsbooks this season.
• In 89 games with a line this season, the Nationals have a mark of 52-37-0 against the spread.
• The Astros have won 28 of the 55 games they were the underdog on the moneyline this season (50.9%).
• Houston is 25-23 (winning 52.1% of its games) when playing as a moneyline underdog of -102 or longer.
• The Astros have played in 92 games with an over/under set, and have combined with their opponents to go over the total 49 times (49-40-3).
• The Astros have a 43-49-0 record ATS this season (covering 46.7% of the time).

Nationals Player Leaders

• James Wood has an OPS of .926, fueled by an OBP of .393 to go with a slugging percentage of .533. He has a .266 batting average, as well.
• Among qualifying hitters in MLB, his batting average ranks 56th, his on-base percentage ranks eighth, and he is 10th in slugging.
• C.J. Abrams has 16 doubles, two triples, 18 home runs and 31 walks. He's batting .269 and slugging .498 with an on-base percentage of .348.
• Among qualifying batters, his batting average ranks him 48th, his on-base percentage 47th, and his slugging percentage 24th.
• Luis Garcia leads Washington with 79 hits. He is batting .282 this season and 37 of his hits have gone for extra bases.
• Daylen Lile has been key for Washington with 89 hits, an OBP of .308 plus a slugging percentage of .417.

Astros Player Leaders

• Yordan Alvarez has racked up a team-best OBP (.429) and slugging percentage (.637), while pacing the Astros in hits (104, while batting .320).
• Including all qualified hitters in the majors, he is fourth in batting average, first in on-base percentage and first in slugging percentage.
• Christian Walker is hitting .238 with 16 doubles, a triple, 20 home runs and 31 walks. He's slugging .470 with an on-base percentage of .311.
• His batting average ranks 111th among all qualified players, his on-base percentage is 115th, and he is 43rd in slugging.
• Isaac Paredes is batting .254 with 16 doubles, 12 home runs and 33 walks.
• Cam Smith is batting .221 with 13 doubles, a triple, 11 home runs and 28 walks.

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