Wednesday’s MLB Odds, Betting Lines and Predictions - July 22

There are plenty of exciting matchups on today's MLB schedule, including the Los Angeles Dodgers taking on the Philadelphia Phillies. Take a look at at the article below, where we provide predictions for each game.

Today's MLB Odds and Predictions

Pittsburgh Pirates at New York Yankees Odds, Lines & Predictions

Game Info

• When: 1:05 p.m. ET
• Where: Yankee Stadium
• TV Channel: YES and SportsNet PT
• Probable Pitchers: Gerrit Cole vs. Mitch Keller
• Records: Yankees (56-45), Pirates (53-49)
• Yankees Moneyline Odds: -198
• Pirates Moneyline Odds: +166

numberFire Prediction

• numberFire Predicted Favorite: Yankees
• Yankees Win Probability: 53.77%
• Pirates Win Probability: 46.23%

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Baltimore Orioles at Boston Red Sox Odds, Lines & Predictions

Game Info

• When: 1:35 p.m. ET
• Where: Fenway Park
• TV Channel: NESN and MASN
• Probable Pitchers: Jake Bennett vs. Dean Kremer
• Records: Red Sox (52-48), Orioles (49-53)
• Red Sox Moneyline Odds: -158
• Orioles Moneyline Odds: +134

numberFire Prediction

• numberFire Predicted Favorite: Red Sox
• Red Sox Win Probability: 61.23%
• Orioles Win Probability: 38.77%

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New York Mets at Milwaukee Brewers Odds, Lines & Predictions

Game Info

• When: 2:10 p.m. ET
• Where: American Family Field
• TV Channel: BREW and SNY
• Probable Pitchers: Logan Henderson vs. Christian Scott
• Records: Brewers (64-38), Mets (43-60)
• Brewers Moneyline Odds: -158
• Mets Moneyline Odds: +134

numberFire Prediction

• numberFire Predicted Favorite: Brewers
• Brewers Win Probability: 58.89%
• Mets Win Probability: 41.11%

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San Francisco Giants at Kansas City Royals Odds, Lines & Predictions

Game Info

• When: 2:10 p.m. ET
• Where: Kauffman Stadium
• TV Channel: ROYL and NBCS-BA
• Probable Pitchers: Seth Lugo vs. Landen Roupp
• Records: Royals (43-60), Giants (42-60)
• Giants Moneyline Odds: -130
• Royals Moneyline Odds: +110

numberFire Prediction

• numberFire Predicted Favorite: Giants
• Giants Win Probability: 58.40%
• Royals Win Probability: 41.60%

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Washington Nationals at Colorado Rockies Odds, Lines & Predictions

Game Info

• When: 3:10 p.m. ET
• Where: Coors Field
• TV Channel: COLR and NATS
• Probable Pitchers: Gabriel Hughes vs. Cade Cavalli
• Records: Rockies (41-62), Nationals (51-51)
• Nationals Moneyline Odds: -144
• Rockies Moneyline Odds: +122

numberFire Prediction

• numberFire Predicted Favorite: Nationals
• Nationals Win Probability: 68.50%
• Rockies Win Probability: 31.50%

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Cincinnati Reds at Seattle Mariners Odds, Lines & Predictions

Game Info

• When: 3:40 p.m. ET
• Where: T-Mobile Park
• TV Channel: SEAM and CINR
• Probable Pitchers: Emerson Hancock vs. Brady Singer
• Records: Mariners (51-51), Reds (46-54)
• Mariners Moneyline Odds: -164
• Reds Moneyline Odds: +138

numberFire Prediction

• numberFire Predicted Favorite: Mariners
• Mariners Win Probability: 63.10%
• Reds Win Probability: 36.90%

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Athletics at Arizona Diamondbacks Odds, Lines & Predictions

Game Info

• When: 3:40 p.m. ET
• Where: Chase Field
• TV Channel: ARID and NBCS-CA
• Probable Pitchers: Merrill Kelly vs. Gage Jump
• Records: Diamondbacks (52-49), Athletics (43-58)
• Diamondbacks Moneyline Odds: -136
• Athletics Moneyline Odds: +116

numberFire Prediction

• numberFire Predicted Favorite: Athletics
• Athletics Win Probability: 55.02%
• Diamondbacks Win Probability: 44.98%

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St. Louis Cardinals at Los Angeles Angels Odds, Lines & Predictions

Game Info

• When: 4:07 p.m. ET
• Where: Angel Stadium
• TV Channel: ABTV and CARD
• Probable Pitchers: Reid Detmers vs. Hunter Dobbins
• Records: Angels (41-61), Cardinals (51-49)
• Angels Moneyline Odds: -142
• Cardinals Moneyline Odds: +120

numberFire Prediction

• numberFire Predicted Favorite: Angels
• Angels Win Probability: 57.37%
• Cardinals Win Probability: 42.63%

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Minnesota Twins at Cleveland Guardians Odds, Lines & Predictions

Game Info

• When: 6:40 p.m. ET
• Where: Progressive Field
• TV Channel: CLEG and MNNT
• Probable Pitchers: Slade Cecconi vs. Bailey Ober
• Records: Guardians (54-48), Twins (49-53)
• Guardians Moneyline Odds: -144
• Twins Moneyline Odds: +122

numberFire Prediction

• numberFire Predicted Favorite: Guardians
• Guardians Win Probability: 51.36%
• Twins Win Probability: 48.64%

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Los Angeles Dodgers at Philadelphia Phillies Odds, Lines & Predictions

Game Info

• When: 6:40 p.m. ET
• Where: Citizens Bank Park
• TV Channel: NBCS-PH and SportsNet LA
• Probable Pitchers: Aaron Nola vs. Eric Lauer
• Records: Phillies (56-46), Dodgers (64-38)
• Dodgers Moneyline Odds: -124
• Phillies Moneyline Odds: +106

numberFire Prediction

• numberFire Predicted Favorite: Dodgers
• Dodgers Win Probability: 57.41%
• Phillies Win Probability: 42.59%

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Pittsburgh Pirates at New York Yankees Odds, Lines & Predictions

Game Info

• When: 7:05 p.m. ET
• Where: Yankee Stadium
• TV Channel: YES and SportsNet PT
• Probable Pitchers: Max Fried vs. Bubba Chandler
• Records: Yankees (56-45), Pirates (53-49)
• Yankees Moneyline Odds: -184
• Pirates Moneyline Odds: +154

numberFire Prediction

• numberFire Predicted Favorite: Yankees
• Yankees Win Probability: 57.14%
• Pirates Win Probability: 42.86%

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Tampa Bay Rays at Toronto Blue Jays Odds, Lines & Predictions

Game Info

• When: 7:07 p.m. ET
• Where: Rogers Centre
• TV Channel: SNET and RAYS
• Probable Pitchers: Braydon Fisher vs. Griffin Jax
• Records: Blue Jays (46-55), Rays (58-42)
• Blue Jays Moneyline Odds: -108
• Rays Moneyline Odds: -108

numberFire Prediction

• numberFire Predicted Favorite: Rays
• Rays Win Probability: 56.35%
• Blue Jays Win Probability: 43.65%

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Baltimore Orioles at Boston Red Sox Odds, Lines & Predictions

Game Info

• When: 7:10 p.m. ET
• Where: Fenway Park
• TV Channel: NESN and MASN
• Probable Pitchers: Eduardo Rivera vs. Kyle Bradish
• Records: Red Sox (52-48), Orioles (49-53)
• Red Sox Moneyline Odds: -120
• Orioles Moneyline Odds: +102

numberFire Prediction

• numberFire Predicted Favorite: Orioles
• Orioles Win Probability: 50.07%
• Red Sox Win Probability: 49.93%

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San Diego Padres at Atlanta Braves Odds, Lines & Predictions

Game Info

• When: 7:15 p.m. ET
• Where: Truist Park
• TV Channel: BravesVsn and SDPA
• Probable Pitchers: Martín Pérez vs. Michael King
• Records: Braves (58-42), Padres (50-51)
• Braves Moneyline Odds: -118
• Padres Moneyline Odds: +100

numberFire Prediction

• numberFire Predicted Favorite: Braves
• Braves Win Probability: 56.87%
• Padres Win Probability: 43.13%

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Chicago White Sox at Texas Rangers Odds, Lines & Predictions

Game Info

• When: 8:05 p.m. ET
• Where: Globe Life Field
• TV Channel: RSN and CHSN
• Probable Pitchers: Tyler Alexander vs. Anthony Kay
• Records: Rangers (51-50), White Sox (53-47)
• White Sox Moneyline Odds: -122
• Rangers Moneyline Odds: +104

numberFire Prediction

• numberFire Predicted Favorite: Rangers
• Rangers Win Probability: 62.56%
• White Sox Win Probability: 37.44%

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Miami Marlins at Houston Astros Odds, Lines & Predictions

Game Info

• When: 8:10 p.m. ET
• Where: Daikin Park
• TV Channel: SCHN and MIAM
• Probable Pitchers: Peter Lambert vs. Sandy Alcantara
• Records: Astros (49-54), Marlins (52-50)
• Astros Moneyline Odds: -116
• Marlins Moneyline Odds: -102

numberFire Prediction

• numberFire Predicted Favorite: Marlins
• Marlins Win Probability: 57.22%
• Astros Win Probability: 42.78%

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Detroit Tigers at Chicago Cubs Odds, Lines & Predictions

Game Info

• When: 8:10 p.m. ET
• Where: Wrigley Field
• TV Channel: ESPN
• Probable Pitchers: Colin Rea vs. Keider Montero
• Records: Cubs (57-44), Tigers (47-54)
• Cubs Moneyline Odds: -120
• Tigers Moneyline Odds: +102

numberFire Prediction

• numberFire Predicted Favorite: Cubs
• Cubs Win Probability: 59.60%
• Tigers Win Probability: 40.40%

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All MLB win probability predictions and picks are according to numberFire.