Mets vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for June 6

Odds updated as of 6:13 a.m.

The Saturday slate in MLB includes a matchup between the New York Mets and the San Diego Padres.

We've got you covered, in terms of the vital information about this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Mets vs Padres Game Info

• New York Mets (28-35) vs. San Diego Padres (32-30)
• Date: Saturday, June 6, 2026
• Time: 10:10 p.m. ET
• Venue: Petco Park -- San Diego, California
• Coverage: Padres.TV and SNY

Mets vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYM: (-124) | SD: (+106)
• Spread: NYM: -1.5 (+132) | SD: +1.5 (-160)
• Total: 7.5 -- Over: (-115) | Under: (-105)

Mets vs Padres Probable Starting Pitchers

Probable Pitchers: Nolan McLean (Mets) - 3-4, 4.21 ERA vs Griffin Canning (Padres) - 0-4, 7.16 ERA

The probable pitchers are Nolan McLean (3-4) for the Mets and Griffin Canning (0-4) for the Padres. McLean and his team have a record of 5-7-0 against the spread when he starts. McLean's team has been victorious in 36.4% of the games he's started as the moneyline favorite with a record of 4-7. The Padres have a 1-5-0 ATS record in Canning's six starts that had a set spread. The Padres were the underdog on the moneyline for three Canning starts this season -- they lost every time.

Mets vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mets win (53.1%)

Mets vs Padres Moneyline

• The Mets vs Padres moneyline has New York as a -124 favorite, while San Diego is a +106 underdog at home.

Mets vs Padres Spread

• The Padres are hosting the Mets, and are +1.5 on the runline. The Padres are +132 to cover the spread, and the Mets are -160.

Mets vs Padres Over/Under

• A combined run total of 7.5 has been set for Mets-Padres on June 6, with the over at -115 and the under at -105.

Bet on New York Mets vs. San Diego Padres on FanDuel today!

Mets vs Padres Betting Trends

• The Mets have come away with 23 wins in the 43 contests they have been listed as the favorites in this season.
• New York has a record of 15-20 in contests when sportsbooks favor them by -124 or more on the moneyline.
• The Mets and their opponents have gone over the total this season in 27 of their 63 opportunities.
• The Mets are 27-36-0 against the spread in their 63 games that had a posted line this season.
• The Padres have won 48.3% of the games this season they were the moneyline underdog (14-15).
• San Diego is 10-12 (winning 45.5% of its games) when playing as a moneyline underdog of +106 or longer.
• The Padres have played in 62 games with a set over/under, and have combined with opponents to go over the total 25 times (25-36-1).
• The Padres are 34-28-0 against the spread this season.

Mets Player Leaders

• Juan Soto has 49 hits and an OBP of .372, both of which rank first among New York hitters this season. He has a .287 batting average and a slugging percentage of .550.
• Among all qualified hitters in MLB, his batting average ranks 26th, his on-base percentage ranks 27th, and he is seventh in slugging.
• Bo Bichette leads New York in slugging percentage (.325) thanks to 13 extra-base hits. He's batting .230 with an on-base percentage of .284.
• His batting average ranks 123rd among qualified players, his on-base percentage 143rd, and his slugging percentage 147th.
• Bichette takes a two-game streak with at least one hit into this matchup. In his last five games he is batting .333 with a double, a triple, a walk and five RBIs.
• Carson Benge has 53 hits this season and has a slash line of .248/.312/.374.
• Marcus Semien has been key for New York with 49 hits, an OBP of .267 plus a slugging percentage of .330.

Padres Player Leaders

• Xander Bogaerts is hitting .228 with three doubles, eight home runs and 22 walks. He's slugging .353 with an on-base percentage of .300.
• He ranks 127th in batting average, 126th in on-base percentage and 126th in slugging percentage among all qualified hitters in the big leagues.
• Gavin Sheets' 41 hits pace his team. He has a batting average of .233 while slugging .460 with an on-base percentage of .328.
• He is 116th in batting average, 87th in on-base percentage and 49th in slugging percentage in the majors.
• Manny Machado is batting .175 with six doubles, 11 home runs and 27 walks.
• Fernando Tatis Jr. leads his team with a .338 on-base percentage, and has a club-high .322 slugging percentage.

Mets vs Padres Head to Head

• 6/5/2026: 5-0 NYM (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/18/2025: 6-1 NYM (Favorite: Mets, Spread: -1.5, Total: 9, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 9/17/2025: 7-4 SD (Favorite: Mets, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/16/2025: 8-3 NYM (Favorite: Mets, Spread: -1.5, Total: 7.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 7/30/2025: 5-0 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 7/29/2025: 7-1 SD (Favorite: Mets, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/28/2025: 7-6 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 8/25/2024: 3-2 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/24/2024: 7-1 NYM (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 8/23/2024: 7-0 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)

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