Mariners vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 26

Odds updated as of 7:13 a.m.

The Seattle Mariners versus the San Diego Padres is on the MLB schedule for Tuesday.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's what you need to know.

Mariners vs Padres Game Info

• Seattle Mariners (71-61) vs. San Diego Padres (74-58)
• Date: Tuesday, August 26, 2025
• Time: 9:40 p.m. ET
• Venue: T-Mobile Park -- Seattle, Washington
• Coverage: ROOT Sports NW and SDPA

Mariners vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SEA: (-112) | SD: (-104)
• Spread: SEA: +1.5 (-200) | SD: -1.5 (+164)
• Total: 8 -- Over: (-105) | Under: (-115)

Mariners vs Padres Probable Starting Pitchers

Probable Pitchers: Luis Castillo (Mariners) - 8-7, 3.57 ERA vs Dylan Cease (Padres) - 6-11, 4.71 ERA

The Mariners will give the ball to Luis Castillo (8-7, 3.57 ERA), who is eyeing win No. 9 on the season, and the Padres will turn to Dylan Cease (6-11, 4.71 ERA). Castillo and his team have a record of 11-15-0 against the spread when he starts. Castillo's team is 11-8 this season when he starts and they are the moneyline favorite. When Cease starts, the Padres have gone 12-14-0 against the spread. The Padres have been the moneyline underdog in seven of Cease's starts this season, and they went 2-5 in those games.

Mariners vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (50.2%)

Mariners vs Padres Moneyline

• The Mariners vs Padres moneyline has Seattle as a -112 favorite, while San Diego is a -104 underdog on the road.

Mariners vs Padres Spread

• The Padres are 1.5-run favorites against the spread for this matchup with the Mariners. The Padres are +164 to cover, while the Mariners are -200 to cover as a 1.5-run underdog on the runline.

Mariners vs Padres Over/Under

• A combined run total of 8 has been set for Mariners-Padres on Aug. 26, with the over at -105 and the under at -115.

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Mariners vs Padres Betting Trends

• The Mariners have won in 50, or 57.5%, of the 87 contests they have been named as odds-on favorites in this year.
• This season Seattle has been victorious 50 times in 85 chances when named as a favorite of at least -112 on the moneyline.
• Contests with the Mariners have gone over the total set by sportsbooks in 67 of 127 chances this season.
• In 127 games with a line this season, the Mariners have a mark of 54-73-0 against the spread.
• The Padres have won 29 of the 59 games they were listed as the moneyline underdog this season (49.2%).
• San Diego has a 28-29 record (winning 49.1% of its games) when playing as a moneyline underdog of -104 or longer.
• The Padres have played in 130 games with an over/under set, and have combined with opponents to go over the total 56 times (56-71-3).
• The Padres have collected a 73-57-0 record ATS this season.

Mariners Player Leaders

• Cal Raleigh leads Seattle with 120 hits, batting .247 this season with 69 extra-base hits. He has an on-base percentage of .353 and a slugging percentage of .596.
• Among all qualified hitters in MLB, he ranks 104th in batting average, 38th in on-base percentage, and third in slugging.
• Raleigh will look for his third straight game with a hit in this matchup. In his last five games he is batting .200 with three home runs and five RBIs.
• Josh Naylor has 24 doubles, a triple, 16 home runs and 43 walks. He's batting .284 and slugging .450 with an on-base percentage of .348.
• Among qualifying batters, he is 26th in batting average, 46th in on-base percentage and 67th in slugging percentage.
• Naylor has picked up at least one hit in four straight games. During his last five outings he is batting .313 with a double, a home run, a walk and four RBIs.
• Julio Rodriguez has hit 25 homers with a team-high .457 SLG this season.
• Rodriguez heads into this matchup with two games in a row with at least one hit. During his last five outings he is batting .278 with a double, a home run, a walk and three RBIs.
• Eugenio Suarez is batting .234 with a .306 OBP and 98 RBI for Seattle this season.

Padres Player Leaders

• Fernando Tatis Jr. has put up a team-best .372 on-base percentage. He's batting .263 and slugging .433.
• Including all the qualifying hitters in MLB, he ranks 61st in batting average, 13th in on-base percentage and 79th in slugging percentage.
• Manny Machado has collected 147 hits while slugging .475. Both pace his team. He has a batting average of .289 with an on-base percentage of .350.
• His batting average is 20th among all qualified players, his on-base percentage ranks 41st, and he is 39th in slugging.
• Luis Arraez has racked up a team-best .393 slugging percentage.
• Xander Bogaerts is batting .262 with 29 doubles, 10 home runs and 48 walks.

Mariners vs Padres Head to Head

• 8/25/2025: 9-6 SEA (Favorite: Mariners, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 5/18/2025: 6-1 SEA (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/17/2025: 4-1 SEA (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 5/16/2025: 5-1 SEA (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 9/11/2024: 5-2 SEA (Favorite: Mariners, Spread: -1.5, Total: 6.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 9/10/2024: 7-3 SD (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/10/2024: 2-0 SEA (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 7/9/2024: 8-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/9/2023: 6-1 SEA (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/8/2023: 2-0 SEA (Favorite: Mariners, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)

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