Mariners vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 26

Odds updated as of 9:12 p.m.

MLB action on Tuesday includes the Seattle Mariners playing the San Diego Padres.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

Mariners vs Padres Game Info

• Seattle Mariners (71-61) vs. San Diego Padres (74-58)
• Date: Tuesday, August 26, 2025
• Time: 9:40 p.m. ET
• Venue: T-Mobile Park -- Seattle, Washington
• Coverage: ROOT Sports NW and SDPA

Mariners vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SEA: (-112) | SD: (-104)
• Spread: SEA: +1.5 (-182) | SD: -1.5 (+150)
• Total: 8 -- Over: (-110) | Under: (-110)

Mariners vs Padres Probable Starting Pitchers

Probable Pitchers: Luis Castillo (Mariners) - 8-7, 3.57 ERA vs Dylan Cease (Padres) - 6-11, 4.71 ERA

The probable starters are Luis Castillo (8-7) for the Mariners and Dylan Cease (6-11) for the Padres. Castillo and his team have a record of 11-15-0 against the spread when he starts. Castillo's team has won 57.9% of his starts when they are favored on the moneyline (11-8). When Cease starts, the Padres have gone 12-14-0 against the spread. The Padres have a 2-5 record in Cease's seven starts this season when they were the moneyline underdog.

Mariners vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (50.1%)

Mariners vs Padres Moneyline

• The Mariners vs Padres moneyline has Seattle as a -112 favorite, while San Diego is a -104 underdog on the road.

Mariners vs Padres Spread

• The Padres are 1.5-run favorites against the spread for this matchup with the Mariners. The Padres are +150 to cover, while the Mariners are -182 to cover as a 1.5-run underdog on the runline.

Mariners vs Padres Over/Under

• An over/under of 8 has been set for Mariners-Padres on Aug. 26, with the over being -110 and the under -110.

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Mariners vs Padres Betting Trends

• The Mariners have won in 50, or 57.5%, of the 87 contests they have been named as odds-on favorites in this year.
• This year Seattle has won 50 of 85 games when listed as at least -112 on the moneyline.
• The Mariners and their opponents have gone over in 67 of their 127 games with a total set by sportsbooks this season.
• The Mariners are 54-73-0 against the spread in their 127 games that had a posted line this season.
• The Padres have won 29 of the 59 games they were listed as the moneyline underdog this season (49.2%).
• When playing as a moneyline underdog with odds of -104 or longer, San Diego has a 28-29 record (winning 49.1% of its games).
• The Padres have played in 130 games with an over/under set, and have combined with their opponents to go over the total 56 times (56-71-3).
• The Padres have covered 56.2% of their games this season, going 73-57-0 ATS.

Mariners Player Leaders

• Cal Raleigh has 120 hits, which leads Seattle hitters this season, while batting .247 with 69 extra-base hits. He has an on-base percentage of .353 and a slugging percentage of .596.
• Among qualifying hitters in the majors, he is 104th in batting average, 37th in on-base percentage, and third in slugging.
• Raleigh will look for his third straight game with a hit in this contest. In his last five games he is batting .200 with three home runs and five RBIs.
• Josh Naylor is hitting .284 with 24 doubles, a triple, 16 home runs and 43 walks, while slugging .450 with an on-base percentage of .348.
• Among all qualifying players, he ranks 26th in batting average, 46th in on-base percentage and 66th in slugging percentage.
• Naylor has picked up a hit in four straight games. During his last five outings he is hitting .313 with a double, a home run, a walk and four RBIs.
• Julio Rodriguez leads Seattle in slugging percentage (.457) powered by 53 extra-base hits.
• Rodriguez heads into this game with two games in a row with at least one hit. In his last five games he is batting .278 with a double, a home run, a walk and three RBIs.
• Eugenio Suarez has 40 home runs, 98 RBI and a batting average of .234 this season.

Padres Player Leaders

• Fernando Tatis Jr. a has .372 on-base percentage to pace the Padres. He's batting .263 while slugging .433.
• Including all qualifying hitters in the majors, he ranks 60th in batting average, 13th in on-base percentage and 79th in slugging percentage.
• Manny Machado's 147 hits and .475 slugging percentage both pace his team. He has a batting average of .289 with an on-base percentage of .350.
• He ranks 20th in batting average, 41st in on-base percentage and 40th in slugging percentage in the big leagues.
• Luis Arraez has a .393 slugging percentage, which paces the Padres.
• Xander Bogaerts is batting .262 with 29 doubles, 10 home runs and 48 walks.

Mariners vs Padres Head to Head

• 8/25/2025: 9-6 SEA (Favorite: Mariners, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 5/18/2025: 6-1 SEA (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/17/2025: 4-1 SEA (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 5/16/2025: 5-1 SEA (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 9/11/2024: 5-2 SEA (Favorite: Mariners, Spread: -1.5, Total: 6.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 9/10/2024: 7-3 SD (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/10/2024: 2-0 SEA (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 7/9/2024: 8-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/9/2023: 6-1 SEA (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/8/2023: 2-0 SEA (Favorite: Mariners, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)

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