Mariners vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 25

Odds updated as of 9:11 p.m.

MLB action on Monday includes the Seattle Mariners taking on the San Diego Padres.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's everything you need to know.

Mariners vs Padres Game Info

• Seattle Mariners (70-61) vs. San Diego Padres (74-57)
• Date: Monday, August 25, 2025
• Time: 9:40 p.m. ET
• Venue: T-Mobile Park -- Seattle, Washington
• Coverage: ROOT Sports NW and SDPA

Mariners vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SEA: (-126) | SD: (+108)
• Spread: SEA: -1.5 (+160) | SD: +1.5 (-194)
• Total: 8.5 -- Over: (-105) | Under: (-115)

Mariners vs Padres Probable Starting Pitchers

Probable Pitchers: Bryce Miller (Mariners) - 2-5, 5.87 ERA vs JP Sears (Padres) - 8-10, 4.94 ERA

The Mariners will give the nod to Bryce Miller (2-5) against the Padres and JP Sears (8-10). Miller and his team have a record of 4-7-0 against the spread when he starts. Miller's team has won 33.3% of his starts when they are favored on the moneyline (2-4). The Padres are 13-11-0 against the spread when Sears starts. The Padres have a 5-11 record in Sears' 16 starts this season when they were the underdog on the moneyline.

Mariners vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mariners win (54%)

Mariners vs Padres Moneyline

• Seattle is the favorite, -126 on the moneyline, while San Diego is a +108 underdog on the road.

Mariners vs Padres Spread

• The Mariners are favored by 1.5 runs at home against the Padres. The Mariners are +160 to cover the spread, while the Padres are -194.

Mariners vs Padres Over/Under

• An over/under of 8.5 has been set for Mariners-Padres on Aug. 25, with the over being -105 and the under -115.

Bet on Seattle Mariners vs. San Diego Padres on FanDuel today!

Mariners vs Padres Betting Trends

• The Mariners have been favorites in 86 games this season and have come away with the win 49 times (57%) in those contests.
• This year Seattle has won 40 of 65 games when listed as at least -126 on the moneyline.
• The Mariners and their opponents have hit the over in 66 of their 126 games with a total set by oddsmakers this season.
• The Mariners have posted a record of 53-73-0 against the spread this season.
• The Padres have won 29 of the 58 games they were the underdog on the moneyline this season (50%).
• San Diego is 21-23 (winning 47.7% of its games) when playing as a moneyline underdog of +108 or longer.
• The Padres have played in 129 games with an over/under set, and have combined with opponents to go over the total 55 times (55-71-3).
• The Padres have a 73-56-0 record ATS this season.

Mariners Player Leaders

• Cal Raleigh has 119 hits, which is tops among Seattle hitters this season, while batting .247 with 68 extra-base hits. He has an on-base percentage of .353 and a slugging percentage of .593.
• Among all qualified hitters, he ranks 105th in batting average, his on-base percentage ranks 38th, and he is third in slugging.
• Julio Rodriguez has hit 25 homers this season while driving in 73 runs. He's batting .259 this season and slugging .459 with an on-base percentage of .313.
• Among qualified hitters, his batting average ranks him 77th, his on-base percentage 110th, and his slugging percentage 55th.
• Josh Naylor has collected 125 base hits, an OBP of .347 and a slugging percentage of .449 this season.
• Naylor has recorded a hit in three straight games. During his last five outings he is batting .188 with a double, a home run, a walk and three RBIs.
• Eugenio Suarez has 40 home runs, 98 RBI and a batting average of .236 this season.

Padres Player Leaders

• Manny Machado has racked up 147 hits with a .480 slugging percentage, both team-high statistics for the Padres. He's batting .292 and with an on-base percentage of .354.
• Including all qualified players in the big leagues, he ranks 14th in batting average, 34th in on-base percentage and 33rd in slugging percentage.
• Fernando Tatis Jr. has a .373 OBP to pace his team. He has a batting average of .264 while slugging .429.
• Including all qualifying hitters, he ranks 57th in batting average, 12th in on-base percentage and 80th in slugging percentage.
• Luis Arraez is batting .285 with 28 doubles, four triples, six home runs and 26 walks.
• Xander Bogaerts has 29 doubles, 10 home runs and 48 walks while batting .262.

Mariners vs Padres Head to Head

• 5/18/2025: 6-1 SEA (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/17/2025: 4-1 SEA (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 5/16/2025: 5-1 SEA (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 9/11/2024: 5-2 SEA (Favorite: Mariners, Spread: -1.5, Total: 6.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 9/10/2024: 7-3 SD (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/10/2024: 2-0 SEA (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 7/9/2024: 8-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/9/2023: 6-1 SEA (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/8/2023: 2-0 SEA (Favorite: Mariners, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/7/2023: 10-3 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)

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