Mariners vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for May 25

Odds updated as of 2:12 p.m.

The Seattle Mariners will face the Houston Astros in MLB action on Sunday.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital info regarding this game.

Mariners vs Astros Game Info

• Seattle Mariners (29-22) vs. Houston Astros (27-25)
• Date: Sunday, May 25, 2025
• Time: 2:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and ROOT Sports NW

Mariners vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SEA: (-138) | HOU: (+118)
• Spread: SEA: -1.5 (+118) | HOU: +1.5 (-142)
• Total: 8.5 -- Over: (-105) | Under: (-115)

Mariners vs Astros Probable Starting Pitchers

Probable Pitchers: Luis Castillo (Mariners) - 4-3, 3.20 ERA vs Colton Gordon (Astros) - 0-0, 5.59 ERA

The Mariners will give the nod to Luis Castillo (4-3, 3.20 ERA), who is eyeing win No. 5 on the season, and the Astros will turn to Colton Gordon. Castillo's team is 5-5-0 against the spread this season in his starts. When Castillo starts a game and his team is the favorite on the moneyline, they have a record of 4-4. Gordon has started two games with set spreads, and the Astros went 1-1-0. The Astros were named the moneyline underdog for one Gordon start this season -- they won.

Mariners vs Astros Moneyline

• Seattle is the favorite, -138 on the moneyline, while Houston is a +118 underdog despite being at home.

Mariners vs Astros Spread

• The Astros are +1.5 on the run line against the Mariners. The Astros are -142 to cover, and the Mariners are +118.

Mariners vs Astros Over/Under

• A combined run total of 8.5 has been set for Mariners-Astros on May 25, with the over at -105 and the under at -115.

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Mariners vs Astros Betting Trends

• The Mariners have won in 17, or 56.7%, of the 30 contests they have been named as odds-on favorites in this year.
• This year Seattle has won 12 of 18 games when listed as at least -138 on the moneyline.
• Contests with the Mariners have gone over the total set by sportsbooks in 27 of 50 chances this season.
• The Mariners are 25-25-0 against the spread in their 50 games with a line set by sportsbooks this season.
• The Astros have put together a 9-8 record in games they were listed as the moneyline underdog (winning 52.9% of those games).
• Houston has played as a moneyline underdog of +118 or longer in just two games this season, which it split 1-1.
• The Astros have played in 52 games with a set over/under, and have combined with opponents to go over the total 21 times (21-29-2).
• The Astros are 28-24-0 ATS this season.

Mariners Player Leaders

• Cal Raleigh has 47 hits to go with a slugging percentage of .584, both of which are best among Seattle hitters this season. He has a .254 batting average and an on-base percentage of .371.
• Among the qualifying hitters in MLB, his batting average ranks 83rd, his on-base percentage ranks 30th, and he is fourth in slugging.
• Julio Rodriguez is hitting .227 with six doubles, two triples, nine home runs and 19 walks, while slugging .409 with an on-base percentage of .305.
• Among qualifying hitters, he is 128th in batting average, 116th in on-base percentage and 89th in slugging percentage.
• Jorge Polanco has collected 37 base hits, an OBP of .338 and a slugging percentage of .562 this season.
• J.P. Crawford leads Seattle in OBP (.379) this season, fueled by 45 hits.

Astros Player Leaders

• Isaac Paredes has 51 hits with a .372 on-base percentage, leading the Astros in both categories. He's batting .267 and slugging .482.
• Including all qualifying hitters, he is 65th in batting average, while his on-base percentage ranks 29th and he is 36th in slugging.
• Jeremy Pena's .439 slugging percentage leads his team. He has a batting average of .296 with an on-base percentage of .361.
• He is 20th in batting average, 42nd in on-base percentage and 62nd in slugging percentage in the majors.
• Jake Meyers has seven doubles, a triple, three home runs and 15 walks while batting .308.
• Jose Altuve has six doubles, six home runs and 15 walks while hitting .253.

Mariners vs Astros Head to Head

• 5/24/2025: 2-1 HOU (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 5/23/2025: 5-3 SEA (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/22/2025: 9-2 HOU (Favorite: Mariners, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 4/9/2025: 7-6 SEA (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/8/2025: 2-1 HOU (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 4/7/2025: 4-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 9/25/2024: 8-1 SEA (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 9/24/2024: 4-3 HOU (Favorite: Astros, Spread: -1.5, Total: 7, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/23/2024: 6-1 SEA (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/21/2024: 6-4 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)

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