Mariners vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for April 11

Odds updated as of 9:11 p.m.

On Saturday in MLB, the Seattle Mariners are playing the Houston Astros.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important information about this matchup.

Mariners vs Astros Game Info

• Seattle Mariners (5-9) vs. Houston Astros (6-8)
• Date: Saturday, April 11, 2026
• Time: 9:40 p.m. ET
• Venue: T-Mobile Park -- Seattle, Washington
• Coverage: Mariners.TV and SCHN

Mariners vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SEA: (-152) | HOU: (+128)
• Spread: SEA: -1.5 (+136) | HOU: +1.5 (-164)
• Total: 7.5 -- Over: (-102) | Under: (-120)

Mariners vs Astros Probable Starting Pitchers

Probable Pitchers: Luis Castillo (Mariners) - 0-0, 2.79 ERA vs Lance McCullers (Astros) - 1-0, 3.27 ERA

This contest's pitching matchup is set, as the Mariners will send Luis Castillo to the mound, while Lance McCullers (1-0) will answer the bell for the Astros. Castillo has a record of 1-1-0 ATS in two starts with a spread this season. Castillo's team lost his only start as a favorite this season. McCullers has started two games with set spreads, and the Astros went 1-1-0. The Astros were the underdog on the moneyline for one McCullers start this season -- they won.

Mariners vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mariners win (56.7%)

Mariners vs Astros Moneyline

• Seattle is the favorite, -152 on the moneyline, while Houston is a +128 underdog on the road.

Mariners vs Astros Spread

• The Astros are +1.5 on the spread (-164 to cover), and Seattle is +136 to cover the runline.

Mariners vs Astros Over/Under

• A combined run total of 7.5 has been set for Mariners-Astros on April 11, with the over at -102 and the under at -120.

Bet on Seattle Mariners vs. Houston Astros on FanDuel today!

Mariners vs Astros Betting Trends

• The Mariners have come away with four wins in the 11 contests they have been listed as the favorites in this season.
• This year Seattle has won two of six games when listed as at least -152 on the moneyline.
• The Mariners' games have gone over the total in six of their 14 opportunities.
• The Mariners are 5-9-0 against the spread in their 14 games with a line set by sportsbooks this season.
• The Astros have won two of the three games they were listed as the moneyline underdog this season (66.7%).
• Houston has not yet played a game with moneyline odds of +128 or longer.
• In the 14 games bookmakers have set an over/under for the Astros, they have combined with opponents to go over the total 10 times (10-4-0).
• The Astros have a 6-8-0 record ATS this season (covering 42.9% of the time).

Mariners Player Leaders

• Randy Arozarena has an OPS of .803, fueled by an OBP of .407 and a team-best slugging percentage of .396 this season. He has a .271 batting average.
• Among qualified hitters in the majors, his batting average ranks 55th, his on-base percentage ranks 19th, and he is 82nd in slugging.
• Brendan Donovan has 12 hits and an OBP of .422, both of which lead the Mariners this season. He's batting .316 and slugging .605.
• His batting average ranks 27th among qualified players, his on-base percentage 10th, and his slugging percentage 15th.
• Cole Young leads Seattle in slugging percentage (.469) powered by five extra-base hits.
• Young heads into this game with three games in a row with at least one hit. During his last five outings he is batting .235 with a home run, three walks and three RBIs.
• Dominic Canzone is batting .207 with a .281 OBP and four RBI for Seattle this season.

Astros Player Leaders

• Yordan Alvarez has totaled 15 hits with a .516 on-base percentage, leading the Astros in both categories. He's batting .341 and slugging .750.
• Including all qualified players in the majors, he is 12th in batting average, first in on-base percentage and third in slugging percentage.
• Christian Walker is slugging .604 to pace his team. He has a batting average of .321 with an on-base percentage of .390.
• His batting average is 21st among all qualified players, his on-base percentage is 30th, and he is 16th in slugging.
• Jose Altuve is batting .306 with four doubles, two home runs and 12 walks.
• Carlos Correa is hitting .261 with two doubles, a home run and six walks.

Mariners vs Astros Head to Head

• 4/10/2026: 9-6 SEA (Favorite: Mariners, Spread: -1.5, Total: 8, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 9/21/2025: 7-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 8.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 9/20/2025: 6-4 SEA (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 9/19/2025: 4-0 SEA (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 7/20/2025: 11-3 HOU (Favorite: Mariners, Spread: -1.5, Total: 6.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 7/19/2025: 7-6 SEA (Favorite: Mariners, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/18/2025: 6-1 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/25/2025: 5-3 HOU (Favorite: Mariners, Spread: -1.5, Total: 8.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 5/24/2025: 2-1 HOU (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 5/23/2025: 5-3 SEA (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)

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