Louisville vs Jackson State College Basketball Prediction, Odds, Picks, Best Bets for Nov. 6

Game day: Thursday, November 6, 2025
Game time: 7 p.m. ET
TV channel: ACC Network Extra
Location: Louisville, Kentucky
Arena: KFC Yum! Center

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The Louisville Cardinals (1-0) take the court against the Jackson State Tigers (0-1) on November 6, 2025.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Louisville vs. Jackson State Game Info and Odds

Here's a look at some betting trends for Louisville (-39.5) versus Jackson State on Thursday. The total is set at 164.5 points for this game.

Louisville put together a 20-15-0 record against the spread last season.
Jackson State won 20 games against the spread last season, while failing to cover 14 times.
The Cardinals did a better job covering the spread in away games (9-2-0) than they did at home (8-9-0) last year.
Against the spread, the Tigers were better at home (7-2-0) than away (11-10-0) last year.

Offensively, Louisville was the 65th-ranked team in the nation (78.5 points per game) last season. Defensively, it was 89th (69.5 points allowed per game).
Last season, Louisville was 47th in college basketball in rebounds (34.6 per game) and 114th in rebounds conceded (30.2).
At 13.9 assists per game last season, Louisville was 148th in the nation.
Last season, Louisville was 150th in the country in turnovers committed (10.9 per game) and 93rd in turnovers forced (12.2).
Jackson State was 247th in college basketball last year with 71.4 points per game. At the other end of the court, it ranked 255th with 74.6 points allowed per game.
Jackson State grabbed 33.3 rebounds per game (96th-ranked in college basketball) last year, while allowing 33.7 rebounds per contest (318th-ranked).
Last year Jackson State ranked 279th in college basketball in assists, delivering 12.2 per game.
With 12.9 turnovers per game, Jackson State was 325th in the nation. It forced 11.9 turnovers per contest, which ranked 121st in college basketball.

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