Knicks vs. Celtics Eastern Semifinals Prediction, Odds, Picks, Best Bets for May 16

Knicks vs. Celtics Game Info

• Date: Friday, May 16, 2025
• Time: 8 p.m. ET
• Venue: Madison Square Garden -- New York City, New York
• Coverage: ESPN

The New York Knicks bring a 3-2 series lead into a decisive Game 6 of the second round of the NBA Playoffs. The Knicks are favored by 2.5 points in the contest, which airs on ESPN at 8 p.m. ET. The matchup's point total is 211.

Knicks vs. Celtics Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Knicks vs. Celtics Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Knicks win (52.6%)

Knicks vs. Celtics Betting Trends

• The Knicks are 40-41-1 against the spread this season.
• The Celtics have played 82 games, with 39 wins against the spread.
• This season, 43 of the Knicks' games have gone over the point total.
• Celtics games this season have gone over the point total 37 times in 82 opportunities (45.1%).
• New York has covered the spread in a higher percentage of its home games than road games. It has covered 21 times in 41 opportunities at home, and it has covered 19 times in 41 opportunities in road games.
• The Knicks have eclipsed the total more often when playing at home, hitting the over in 23 of 41 home matchups (56.1%). In road games, they have hit the over in 20 of 41 games (48.8%).
• Against the spread, Boston has had better results on the road (21-19-1) than at home (18-23-0).
• In 2024-25, a higher percentage of the Celtics' games have finished above the over/under at home (51.2%, 21 of 41) than on the road (39%, 16 of 41).

Knicks Leaders

• Karl-Anthony Towns is averaging 24.4 points, 3.1 assists and 12.8 rebounds.
• Josh Hart averages 13.6 points, 9.6 boards and 5.9 assists, shooting 52.5% from the field and 33.3% from downtown, with 1.1 made 3-pointers per game.
• Jalen Brunson is averaging 26 points, 2.9 boards and 7.3 assists. At the other end, he averages 0.9 steals and 0.1 blocked shots.
• Mikal Bridges' numbers on the season are 17.6 points, 3.2 rebounds and 3.7 assists per game, shooting 50% from the field and 35.4% from downtown, with an average of 2 made 3-pointers.
• OG Anunoby's numbers on the season are 18 points, 4.8 rebounds and 2.2 assists per game, shooting 47.6% from the floor and 37.2% from downtown, with an average of 2.3 made treys.

Celtics Leaders

• Derrick White averages 16.4 points, 4.5 boards and 4.8 assists. He is also sinking 44.2% of his shots from the field and 38.4% from beyond the arc, with 3.5 triples per game (fourth in league).
• The Celtics receive 22.2 points per game from Jaylen Brown, plus 5.8 rebounds and 4.5 assists.
• Payton Pritchard's numbers on the season are 14.3 points, 3.8 rebounds and 3.5 assists per game. He is sinking 47.2% of his shots from the field and 40.7% from beyond the arc, with an average of 3.2 triples (10th in NBA).
• Jrue Holiday averages 11.1 points, 4.3 rebounds and 3.9 assists. He is sinking 44.3% of his shots from the field and 35.3% from beyond the arc, with 1.7 treys per game.
• Kristaps Porzingis averages 19.5 points, 6.8 boards and 2.1 assists. He is sinking 48.3% of his shots from the floor and 41.2% from 3-point range, with 2.5 treys per contest.

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