Houston vs Rice Prediction, Odds, Picks, Best Bets for Week 2 2025

College football's Saturday slate includes the Houston Cougars taking on the Rice Owls.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NCAA football betting insights.

Houston vs Rice Odds & Spread

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Houston: (-629) | Rice: (+450)
• Spread: Houston: -13.5 (-114) | Rice: +13.5 (-106)
• Total: 38.5 -- Over: (-115) | Under: (-105)

Houston vs Rice Betting Trends

• Houston has covered the spread in every game this season.
• Houston is unbeaten ATS (1-0) as a 13.5-point favorite or greater this season.
• Rice is unbeaten against the spread this season.
• Rice and its opponent have yet to go over the total this season.

Houston vs Rice Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Cougars win (80.9%)

Houston vs Rice Point Spread

Rice is the underdog by 13.5 points against Houston. Rice is -114 to cover the spread, and Houston is -106.

Houston vs Rice Over/Under

The over/under for Houston-Rice on Sept. 6 is 38.5. The over is -115, and the under is -105.

Houston vs Rice Moneyline

The Houston vs Rice moneyline has Houston as a -629 favorite, while Rice is a +450 underdog.

Houston vs. Rice Points Insights

• The average implied total for the Cougars last season was 28.2 points, 2.2 more points than their implied total of 26 points in Saturday's game.
• The 30.0-point average implied total last season for the Owls is 17.0 more points than the team's 13-point implied total in this matchup.

Houston vs. Rice Game Info

• Game day: Saturday, September 6, 2025
• Game time: 7 p.m. ET
• TV channel: ESPN+
• Location: Houston, Texas
• Stadium: Rice Stadium

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

Check out even more in-depth Houston vs. Rice analysis on FanDuel Research.