Guardians vs Yankees Prediction, Odds, Moneyline, Spread & Over/Under for June 10

Odds updated as of 12:12 p.m.

The Cleveland Guardians are among the MLB squads in action on Wednesday, versus the New York Yankees.

We've got you covered, in terms of the vital information about this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Guardians vs Yankees Game Info

• Cleveland Guardians (37-32) vs. New York Yankees (40-26)
• Date: Wednesday, June 10, 2026
• Time: 1:10 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: CleGuardians.TV and YES

Guardians vs Yankees Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-120) | NYY: (+102)
• Spread: CLE: +1.5 (-205) | NYY: -1.5 (+168)
• Total: 7.5 -- Over: (-118) | Under: (-104)

Guardians vs Yankees Probable Starting Pitchers

Probable Pitchers: Parker Messick (Guardians) - 6-2, 2.40 ERA vs Carlos Rodon (Yankees) - 1-2, 2.88 ERA

The Guardians will give the ball to Parker Messick (6-2, 2.40 ERA), who is eyeing win No. 7 on the season, and the Yankees will counter with Carlos Rodon (1-2, 2.88 ERA). When Messick starts, his team is 8-5-0 against the spread this season. Messick's team has won 60% of his starts when they are favored on the moneyline (6-4). The Yankees are 1-4-0 against the spread when Rodon starts. The Yankees were named the moneyline underdog for one Rodon start this season -- they lost.

Guardians vs Yankees Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Yankees win (51.3%)

Guardians vs Yankees Moneyline

• The moneyline numbers for Guardians vs. Yankees reveal Cleveland as the favorite (-120) and New York as the underdog (+102) on the road.

Guardians vs Yankees Spread

• The Yankees are 1.5-run favorites against the spread for this matchup with the Guardians. The Yankees are +168 to cover, while the Guardians are -205 to cover as a 1.5-run underdog on the runline.

Guardians vs Yankees Over/Under

• An over/under of 7.5 has been set for Guardians-Yankees on June 10, with the over being -118 and the under -104.

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Guardians vs Yankees Betting Trends

• The Guardians have been chosen as favorites in 36 games this year and have walked away with the win 19 times (52.8%) in those games.
• This year Cleveland has won 15 of 29 games when listed as at least -120 on the moneyline.
• The Guardians' games have gone over the total in 33 of their 65 opportunities.
• The Guardians are 33-32-0 against the spread in their 65 games with a line set by sportsbooks this season.
• The Yankees have won three of the five games they were the underdog on the moneyline this season (60%).
• New York has played as a moneyline underdog of +102 or longer in just two games this season, which it won both.
• The Yankees have combined with opponents to hit the over on the total 28 times this season for a 28-32-3 record against the over/under.
• The Yankees have a 31-32-0 record ATS this season (covering 49.2% of the time).

Guardians Player Leaders

• Jose Ramirez has an OPS of .768, fueled by an OBP of .344 and a team-best slugging percentage of .424 this season. He has a .241 batting average.
• Among all qualifying batters in MLB, his batting average ranks 100th, his on-base percentage ranks 62nd, and he is 75th in slugging.
• Ramirez will look for his third straight game with a hit in this matchup. In his last five games he is hitting .200 with a home run, two walks and an RBI.
• Brayan Rocchio leads Cleveland with an OBP of .363 this season while batting .280 with 22 walks and 28 runs scored. He's slugging .402.
• He ranks 36th in batting average, 39th in on-base percentage and 93rd in slugging in MLB.
• Chase DeLauter has collected 60 base hits, an OBP of .328 and a slugging percentage of .398 this season.
• DeLauter has logged a hit or more in four games in a row. During his last five outings he is hitting .227 with a walk and two RBIs.
• Angel Martinez leads Cleveland with 51 hits, batting .236 this season with 21 extra-base hits.
• Martinez has hit safely in three straight games. In his last five games he is hitting .222 with a home run, a walk and three RBIs.

Yankees Player Leaders

• Ben Rice has accumulated a team-best OBP (.392) and slugging percentage (.626), and paces the Yankees in hits (66, while batting .297).
• Including all qualified hitters, he is 18th in batting average, while his on-base percentage ranks ninth and he is second in slugging.
• Cody Bellinger has 13 doubles, three triples, nine home runs and 40 walks while batting .272. He's slugging .468 with an on-base percentage of .371.
• Including all qualifying hitters, he is 47th in batting average, 28th in on-base percentage and 43rd in slugging percentage.
• Trent Grisham has 11 doubles, a triple, eight home runs and 37 walks while batting .227.
• Jazz Chisholm has 10 doubles, a triple, nine home runs and 25 walks while batting .231.

Guardians vs Yankees Head to Head

• 6/9/2026: 3-2 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/8/2026: 7-5 NYY (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 6/4/2026: 2-1 NYY (Favorite: Yankees, Spread: -1.5, Total: 9, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 6/3/2026: 5-4 CLE (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 6/2/2026: 9-4 CLE (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 6/5/2025: 4-0 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -275, Underdog Moneyline: +225)
• 6/4/2025: 4-0 CLE (Favorite: Yankees, Spread: -1.5, Total: 9, Favorite Moneyline: -196, Underdog Moneyline: +164)
• 6/3/2025: 3-2 NYY (Favorite: Yankees, Spread: -1.5, Total: 8, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 4/23/2025: 5-1 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 4/22/2025: 3-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)

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