Cardinals vs Reds Prediction, Odds, Moneyline, Spread & Over/Under for July 25

Odds updated as of 7:12 p.m.

Saturday's slate in the MLB includes a matchup between the St. Louis Cardinals and the Cincinnati Reds.

All the info you need to make smart bets on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Cardinals vs Reds Game Info

• St. Louis Cardinals (52-51) vs. Cincinnati Reds (48-54)
• Date: Saturday, July 25, 2026
• Time: 7:15 p.m. ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: Cardinals.TV and Reds.TV

Cardinals vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: STL: (-152) | CIN: (+128)
• Spread: STL: -1.5 (+146) | CIN: +1.5 (-176)
• Total: 8 -- Over: (-106) | Under: (-114)

Cardinals vs Reds Probable Starting Pitchers

Probable Pitchers: Andre Pallante (Cardinals) - 10-6, 4.02 ERA vs Hunter Greene (Reds) - 2-1, 6.06 ERA

The Cardinals will give the nod to Andre Pallante (10-6, 4.02 ERA), who is eyeing win No. 11 on the season, and the Reds will turn to Hunter Greene (2-1, 6.06 ERA). Pallante and his team have a record of 12-7-0 against the spread when he starts. Pallante's team has won 42.9% of his starts when they are favored on the moneyline (3-4). The Reds are 2-1-0 against the spread when Greene starts. The Reds were the underdog on the moneyline for one Greene start this season -- they won.

Cardinals vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (57%)

Cardinals vs Reds Moneyline

• The Cardinals vs Reds moneyline has St. Louis as a -152 favorite, while Cincinnati is a +128 underdog on the road.

Cardinals vs Reds Spread

• The Reds are +1.5 on the run line against the Cardinals. The Reds are -176 to cover, and the Cardinals are +146.

Cardinals vs Reds Over/Under

• Cardinals versus Reds, on July 25, has an over/under of 8, with the over being -106 and the under -114.

Bet on St. Louis Cardinals vs. Cincinnati Reds on FanDuel today!

Cardinals vs Reds Betting Trends

• The Cardinals have been chosen as favorites in 29 games this year and have walked away with the win 16 times (55.2%) in those games.
• This season St. Louis has come away with a win three times in four chances when named as a favorite of at least -152 on the moneyline.
• Contests with the Cardinals have gone over the total set by bookmakers in 41 of 101 chances this season.
• In 101 games with a line this season, the Cardinals have a mark of 56-45-0 against the spread.
• The Reds have won 32 of the 68 games they were the moneyline underdog this season (47.1%).
• Cincinnati has a 6-13 record (winning only 31.6% of its games) when it has played as a moneyline underdog of +128 or longer.
• The Reds have played in 100 games with a set over/under, and have combined with their opponents to go over the total 55 times (55-44-1).
• The Reds have covered 55% of their games this season, going 55-45-0 ATS.

Cardinals Player Leaders

• Jordan Walker has 112 hits to go with a slugging percentage of .514, both of which are best among St. Louis hitters this season. He has a .288 batting average and an on-base percentage of .349.
• Among qualifying batters, he is 17th in batting average, his on-base percentage ranks 52nd, and he is 16th in slugging.
• Alec Burleson is batting .281 with 25 doubles, a triple, 15 home runs and 34 walks. He's slugging .464 with an on-base percentage of .342.
• Among qualifying hitters, his batting average ranks him 31st, his on-base percentage 61st, and his slugging percentage 41st.
• JJ Wetherholt is batting .258 with a .401 slugging percentage and 40 RBI this year.
• Ivan Herrera leads St. Louis with an OBP of .365 this season while batting .239 with 51 walks and 63 runs scored.

Reds Player Leaders

• Sal Stewart has racked up a slugging percentage of .471, a team-best for the Reds. He's batting .251 with an on-base percentage of .328.
• Including all the qualifying hitters in MLB, his batting average ranks 82nd, his on-base percentage is 80th, and he is 38th in slugging.
• Elly De La Cruz leads his team with 91 hits and a .352 on-base percentage. He has a batting average of .276 while slugging .500.
• He is 39th in batting average, 46th in on-base percentage and 21st in slugging percentage in the big leagues.
• Spencer Steer is hitting .240 with 14 doubles, 16 home runs and 35 walks.
• JJ Bleday is batting .236 with 11 doubles, a triple, 17 home runs and 41 walks.

Cardinals vs Reds Head to Head

• 7/24/2026: 4-2 CIN (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 6/7/2026: 5-3 STL (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 6/6/2026: 6-5 STL (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 6/5/2026: 10-3 STL (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/23/2026: 7-6 CIN (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 5/23/2026: 8-1 STL (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 9/17/2025: 6-2 CIN (Favorite: Reds, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 9/16/2025: 3-0 STL (Favorite: Reds, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 9/15/2025: 11-6 CIN (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/31/2025: 7-4 CIN (Favorite: Reds, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)

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