Guardians vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 10

Odds updated as of 1:13 p.m.

The MLB slate on Sunday includes the Cleveland Guardians taking on the Chicago White Sox.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

Guardians vs White Sox Game Info

• Cleveland Guardians (61-55) vs. Chicago White Sox (42-75)
• Date: Sunday, August 10, 2025
• Time: 2:10 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and CLEG

Guardians vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-126) | CHW: (+108)
• Spread: CLE: -1.5 (+126) | CHW: +1.5 (-152)
• Total: 9 -- Over: (-102) | Under: (-120)

Guardians vs White Sox Probable Starting Pitchers

Probable Pitchers: Slade Cecconi (Guardians) - 5-4, 3.72 ERA vs Davis Martin (White Sox) - 3-9, 4.11 ERA

The probable pitchers are Slade Cecconi (5-4) for the Guardians and Davis Martin (3-9) for the White Sox. Cecconi's team is 9-4-0 against the spread this season in his starts. Cecconi's team has been victorious in 66.7% of the games he's started as the moneyline favorite with a record of 4-2. The White Sox are 7-8-0 ATS in Martin's 15 starts that had a set spread. The White Sox have a 4-11 record in Martin's 15 starts this season when they were the moneyline underdog.

Guardians vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: White Sox win (51%)

Guardians vs White Sox Moneyline

• Chicago is the underdog, +108 on the moneyline, while Cleveland is a -126 favorite despite being on the road.

Guardians vs White Sox Spread

• The White Sox are at +1.5 on the runline against the Guardians. The White Sox are -152 to cover the spread, and the Guardians are +126.

Guardians vs White Sox Over/Under

• An over/under of 9 has been set for Guardians-White Sox on Aug. 10, with the over being -102 and the under -120.

Bet on Cleveland Guardians vs. Chicago White Sox on FanDuel today!

Guardians vs White Sox Betting Trends

• The Guardians have been favorites in 47 games this season and have come away with the win 31 times (66%) in those contests.
• This season Cleveland has come away with a win 21 times in 28 chances when named as a favorite of at least -126 on the moneyline.
• Contests with the Guardians have gone over the total set by sportsbooks in 51 of 113 chances this season.
• The Guardians have posted a record of 60-53-0 against the spread this season.
• The White Sox have won 38 of the 109 games they were the moneyline underdog this season (34.9%).
• Chicago is 37-66 (winning just 35.9% of its games) when it has played as a moneyline underdog of +108 or longer.
• The White Sox have played in 112 games with an over/under set, and have combined with their opponents to go over the total 50 times (50-54-8).
• The White Sox have a 61-51-0 record ATS this season.

Guardians Player Leaders

• Jose Ramirez leads Cleveland with 125 hits and an OBP of .368, plus a team-best slugging percentage of .515. He's batting .293.
• Among all qualifying hitters in baseball, he ranks 13th in batting average, 17th in on-base percentage, and 13th in slugging.
• Steven Kwan is hitting .280 with 21 doubles, a triple, nine home runs and 40 walks, while slugging .394 with an on-base percentage of .340.
• He is 29th in batting average, 56th in on-base percentage and 112th in slugging among qualified hitters.
• Carlos Santana has collected 86 base hits, an OBP of .319 and a slugging percentage of .340 this season.
• Kyle Manzardo is batting .241 with a .321 OBP and 50 RBI for Cleveland this season.
• Manzardo takes a three-game hitting streak into this matchup. During his last five outings he is batting .333 with a double, four walks and two RBIs.

White Sox Player Leaders

• Andrew Benintendi has 13 doubles, two triples, 14 home runs and 29 walks while hitting .226. He's slugging .416 with an on-base percentage of .292.
• Luis Robert is hitting .222 with 10 doubles, 12 home runs and 38 walks. He's slugging .362 with an on-base percentage of .304.
• He ranks 150th in batting average, 124th in on-base percentage and 145th in slugging percentage in the big leagues.
• Lenyn Sosa has racked up 98 hits with a .305 on-base percentage and a .434 slugging percentage, all club-bests for the White Sox.
• Mike Tauchman has 13 doubles, a triple, eight home runs and 31 walks while batting .273.

Guardians vs White Sox Head to Head

• 8/9/2025: 3-1 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 8/8/2025: 9-5 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/13/2025: 6-5 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 7/12/2025: 6-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 9, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/11/2025: 5-4 CHW (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 7/11/2025: 4-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/10/2025: 6-1 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -245, Underdog Moneyline: +200)
• 4/9/2025: 3-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 4/8/2025: 1-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 7, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 9/11/2024: 6-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -235, Underdog Moneyline: +194)

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