Guardians vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for July 5

Odds updated as of 1:12 p.m.

In MLB action on Sunday, the Cleveland Guardians take on the Chicago White Sox.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Guardians vs White Sox Game Info

• Cleveland Guardians (47-43) vs. Chicago White Sox (46-42)
• Date: Sunday, July 5, 2026
• Time: 2 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: Peacock and NBCSN Extra

Guardians vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-136) | CHW: (+116)
• Spread: CLE: -1.5 (+155) | CHW: +1.5 (-188)
• Total: 8.5 -- Over: (-106) | Under: (-114)

Guardians vs White Sox Probable Starting Pitchers

Probable Pitchers: Tanner Bibee (Guardians) - 2-9, 3.69 ERA vs Chris Murphy (White Sox) - 2-0, 3.79 ERA

This contest's pitching matchup is set, as the Guardians will send Tanner Bibee (2-9) to the mound, while Chris Murphy (2-0) will answer the bell for the White Sox. When Bibee starts, his team is 3-14-0 against the spread this season. Bibee's team is 3-7 this season when he starts and they are the moneyline favorite. Murphy has started just one game with a set spread, which the White Sox covered. The White Sox were named the moneyline underdog for one Murphy start this season -- they lost.

Guardians vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: White Sox win (51.6%)

Guardians vs White Sox Moneyline

• The moneyline numbers for Guardians vs. White Sox reveal Cleveland as the favorite (-136) and Chicago as the underdog (+116) on the road.

Guardians vs White Sox Spread

• The White Sox are at the Guardians, and are +1.5 on the runline. The White Sox are +155 to cover the spread, and the Guardians are -188.

Guardians vs White Sox Over/Under

• Guardians versus White Sox, on July 5, has an over/under of 8.5, with the over being -106 and the under -114.

Bet on Cleveland Guardians vs. Chicago White Sox on FanDuel today!

Guardians vs White Sox Betting Trends

• The Guardians have won in 25, or 53.2%, of the 47 contests they have been named as odds-on favorites in this year.
• Cleveland has a record of 9-7 in contests when oddsmakers favor them by -136 or more on the moneyline.
• Contests with the Guardians have gone over the total set by sportsbooks in 42 of 86 chances this season.
• The Guardians are 43-43-0 against the spread in their 86 games with a line set by sportsbooks this season.
• The White Sox have been the underdog on the moneyline 72 total times this season. They've finished 35-37 in those games.
• Chicago has a 21-24 record (winning 46.7% of its games) when playing as a moneyline underdog of +116 or longer.
• The White Sox have had an over/under set by bookmakers 86 times, and have combined with opponents to go over the total in 48 of those games (48-37-1).
• The White Sox have collected a 50-36-0 record against the spread this season (covering 58.1% of the time).

Guardians Player Leaders

• Brayan Rocchio has an OPS of .738, fueled by an OBP of .345 to go with a slugging percentage of .392. He has a .273 batting average, as well.
• Among qualified hitters in the majors, his batting average ranks 41st, his on-base percentage ranks 55th, and he is 102nd in slugging.
• Rocchio hopes to build on a four-game hitting streak in this matchup. During his last five outings he is hitting .313 with a home run, two walks and three RBIs.
• Chase DeLauter is hitting .269 with 15 doubles, a triple, seven home runs and 28 walks. He's slugging .410 with an on-base percentage of .336.
• Among qualified hitters, his batting average places him 46th, his on-base percentage 68th, and his slugging percentage 93rd.
• Steven Kwan has collected 61 base hits, an OBP of .325 and a slugging percentage of .276 this season.
• Kwan has recorded at least one base hit in seven straight games. In his last 10 games he is batting .313 with two triples, three walks and an RBI.
• Travis Bazzana is batting .250 with a .341 OBP and 27 RBI for Cleveland this season.

White Sox Player Leaders

• Miguel Vargas has accumulated 78 hits, a team-best for the White Sox. He's batting .245 and slugging .491 with an on-base percentage of .357.
• Including all qualified players, he ranks 97th in batting average, while his on-base percentage is 41st and he is 29th in slugging.
• Colson Montgomery has 16 doubles, 22 home runs and 30 walks while hitting .221. He's slugging .484 with an on-base percentage of .308.
• He is currently 132nd in batting average, 122nd in on-base percentage and 33rd in slugging percentage among all qualified hitters.
• Sam Antonacci a has .384 on-base percentage to lead the White Sox.
• Chase Meidroth paces his team with a .379 slugging percentage.

Guardians vs White Sox Head to Head

• 7/4/2026: 3-1 CHW (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 7/3/2026: 4-3 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/2/2026: 6-5 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/24/2026: 4-3 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/23/2026: 2-1 CHW (Favorite: Guardians, Spread: -1.5, Total: 7, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/22/2026: 6-5 CHW (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 9/14/2025: 3-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 9/13/2025: 3-1 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 9/12/2025: 4-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 8/10/2025: 6-4 CHW (Favorite: Guardians, Spread: -1.5, Total: 9, Favorite Moneyline: -126, Underdog Moneyline: +108)

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