Guardians vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for July 3

Odds updated as of 2:12 a.m.

The Cleveland Guardians are among the MLB squads busy on Friday, up against the Chicago White Sox.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

Guardians vs White Sox Game Info

• Cleveland Guardians (46-42) vs. Chicago White Sox (45-41)
• Date: Friday, July 3, 2026
• Time: 7:10 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: CleGuardians.TV and CHSN

Guardians vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-132) | CHW: (+112)
• Spread: CLE: -1.5 (+158) | CHW: +1.5 (-192)
• Total: 8.5 -- Over: (-102) | Under: (-120)

Guardians vs White Sox Probable Starting Pitchers

Probable Pitchers: Gavin Williams (Guardians) - 9-4, 3.81 ERA vs Anthony Kay (White Sox) - 6-3, 4.50 ERA

This contest's pitching matchup is set, as the Guardians will send Gavin Williams (9-4) to the mound, while Anthony Kay (6-3) will answer the bell for the White Sox. Williams' team is 9-7-0 against the spread in his starts this season. When Williams starts a game and his team is the favorite on the moneyline, they have a record of 7-4. The White Sox have a 9-5-0 record against the spread in Kay's starts. The White Sox are 8-5 in Kay's 13 starts this season that they were the underdog on the moneyline.

Guardians vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Guardians win (55.7%)

Guardians vs White Sox Moneyline

• Chicago is the underdog, +112 on the moneyline, while Cleveland is a -132 favorite at home.

Guardians vs White Sox Spread

• The White Sox are at +1.5 on the runline against the Guardians. The White Sox are -192 to cover the spread, and the Guardians are +158.

Guardians vs White Sox Over/Under

• Guardians versus White Sox, on July 3, has an over/under of 8.5, with the over being -102 and the under -120.

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Guardians vs White Sox Betting Trends

• The Guardians have been favorites in 45 games this season and have come away with the win 24 times (53.3%) in those contests.
• This season Cleveland has come away with a win 10 times in 17 chances when named as a favorite of at least -132 on the moneyline.
• The Guardians and their opponents have hit the over in 42 of their 84 games with a total set by oddsmakers this season.
• The Guardians have posted a record of 43-41-0 against the spread this season.
• The White Sox have won 48.6% of the games this season they were the underdog on the moneyline (34-36).
• Chicago has a record of 26-25 in games it has played as a moneyline underdog with odds of +112 or longer (51%).
• The White Sox have played in 84 games with an over/under set, and have combined with their opponents to go over the total 48 times (48-35-1).
• The White Sox have covered 57.1% of their games this season, going 48-36-0 against the spread.

Guardians Player Leaders

• Brayan Rocchio leads Cleveland with an OBP of .342, plus a team-best slugging percentage of .392. He's batting .269 on the season.
• Among all qualifying hitters in the majors, his batting average ranks 50th, his on-base percentage ranks 56th, and he is 106th in slugging.
• Rocchio will look for his third straight game with a hit in this matchup. During his last five outings he is hitting .278 with a home run, two walks and three RBIs.
• Chase DeLauter has 72 hits, which is tops among Cleveland batters this season. He's batting .274 with 23 extra-base hits. He's also slugging .418 with an on-base percentage of .341.
• Among all qualifying players, he is 39th in batting average, 59th in on-base percentage and 86th in slugging percentage.
• DeLauter enters this matchup looking to extend his 11-game hit streak. In his last 10 outings he is batting .375 with four doubles, two walks and six RBIs.
• Travis Bazzana is batting .251 with a .420 slugging percentage and 26 RBI this year.
• Steven Kwan has been key for Cleveland with 59 hits, an OBP of .325 plus a slugging percentage of .267.
• Kwan takes a five-game hitting streak into this game. During his last five outings he is hitting .333 with a triple and three walks.

White Sox Player Leaders

• Miguel Vargas has accumulated 76 hits, a team-best for the White Sox. He's batting .244 and slugging .484 with an on-base percentage of .355.
• Including all the qualifying hitters in the majors, his batting average ranks 95th, his on-base percentage is 43rd, and he is 32nd in slugging.
• Sam Antonacci has a .394 on-base percentage to pace his team. He has a batting average of .299 while slugging .433.
• He is currently 10th in batting average, eighth in on-base percentage and 71st in slugging percentage among all qualified batters.
• Colson Montgomery is batting .221 with 15 doubles, 21 home runs and 30 walks.
• Chase Meidroth's .387 slugging percentage leads his team.

Guardians vs White Sox Head to Head

• 7/2/2026: 6-5 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/24/2026: 4-3 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/23/2026: 2-1 CHW (Favorite: Guardians, Spread: -1.5, Total: 7, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/22/2026: 6-5 CHW (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 9/14/2025: 3-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 9/13/2025: 3-1 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 9/12/2025: 4-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 8/10/2025: 6-4 CHW (Favorite: Guardians, Spread: -1.5, Total: 9, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 8/9/2025: 3-1 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 8/8/2025: 9-5 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)

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