Guardians vs Reds Prediction, Odds, Moneyline, Spread & Over/Under for June 10

Odds updated as of 6:12 p.m.

In MLB action on Tuesday, the Cincinnati Reds take on the Cleveland Guardians.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important information regarding this game.

Reds vs Guardians Game Info

• Cincinnati Reds (34-33) vs. Cleveland Guardians (34-31)
• Date: Tuesday, June 10, 2025
• Time: 6:40 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: CLEG and FDSOH

Reds vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CIN: (-110) | CLE: (-106)
• Spread: CIN: -1.5 (+140) | CLE: +1.5 (-170)
• Total: 8.5 -- Over: (-102) | Under: (-120)

Reds vs Guardians Probable Starting Pitchers

Probable Pitchers: Andrew Abbott (Reds) - 5-1, 2.18 ERA vs Slade Cecconi (Guardians) - 1-2, 4.87 ERA

The Reds will give the nod to Andrew Abbott (5-1, 2.18 ERA), who is eyeing win No. 6 on the season, and the Guardians will counter with Slade Cecconi (1-2, 4.87 ERA). Abbott and his team are 7-2-0 ATS this season when he starts. Abbott's team has a record of 3-1 this season when he starts and they are the favorite on the moneyline. When Cecconi starts, the Guardians have gone 2-2-0 against the spread. The Guardians were the underdog on the moneyline for two Cecconi starts this season -- they split the games.

Reds vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Reds win (56.8%)

Reds vs Guardians Moneyline

• Cleveland is the underdog, -106 on the moneyline, while Cincinnati is a -110 favorite despite being on the road.

Reds vs Guardians Spread

• The Reds are 1.5-run road favorites on the runline against the Guardians. The Reds are +140 to cover, and the Guardians are -170.

Reds vs Guardians Over/Under

• Reds versus Guardians on June 10 has an over/under of 8.5 runs, with the odds on the over -102 and the under set at -120.

Bet on Cincinnati Reds vs. Cleveland Guardians on FanDuel today!

Reds vs Guardians Betting Trends

• The Reds have been favorites in 26 games this season and have come away with the win 13 times (50%) in those contests.
• This season Cincinnati has been victorious 13 times in 26 chances when named as a favorite of at least -110 on the moneyline.
• Contests with the Reds have gone over the total set by sportsbooks in 27 of 64 chances this season.
• The Reds have posted a record of 35-29-0 against the spread this season.
• The Guardians are 18-21 in games they were the underdog on the moneyline (winning 46.2% of those games).
• Cleveland has a 17-21 record (winning 44.7% of its games) when playing as a moneyline underdog of -106 or longer.
• The Guardians have had an over/under set by bookmakers 63 times, and have combined with opponents to go over the total in 29 of those games (29-32-2).
• The Guardians have a 30-33-0 record against the spread this season.

Reds Player Leaders

• Elly De La Cruz leads Cincinnati with 65 hits, batting .256 this season with 25 extra-base hits. He has an on-base percentage of .338 and a slugging percentage of .449.
• Among qualifying hitters in baseball, he ranks 82nd in batting average, 65th in on-base percentage, and 59th in slugging.
• TJ Friedl is slashing .295/.384/.432 this season and leads the Reds with an OPS of .815.
• Among qualifying batters, he ranks 19th in batting average, 15th in on-base percentage and 72nd in slugging percentage.
• Gavin Lux is batting .281 with a .393 slugging percentage and 27 RBI this year.
• Jose Trevino has four home runs, 13 RBI and a batting average of .304 this season.
• Trevino has safely hit in three games in a row. In his last five games he is batting .353 with two doubles, a home run, a walk and an RBI.

Guardians Player Leaders

• Jose Ramirez has racked up a team-best OBP (.393) and slugging percentage (.553), while leading the Guardians in hits (79, while batting .333).
• Including all qualified hitters, he is fourth in batting average, while his on-base percentage is 11th and he is eighth in slugging.
• Ramirez takes a nine-game hitting streak into this game. During his last 10 outings he is hitting .389 with a double, three home runs, seven walks and five RBIs.
• Steven Kwan has 14 doubles, five home runs and 22 walks while hitting .309. He's slugging .427 with an on-base percentage of .370.
• He is currently 14th in batting average, 26th in on-base percentage and 78th in slugging percentage among all qualified batters.
• Carlos Santana has six doubles, seven home runs and 32 walks while batting .256.
• Kyle Manzardo has six doubles, two triples, 11 home runs and 23 walks while hitting .203.

Reds vs Guardians Head to Head

• 6/9/2025: 7-4 CIN (Favorite: Guardians, Spread: -1.5, Total: 9, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 5/18/2025: 3-1 CIN (Favorite: Reds, Spread: -1.5, Total: 9, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 5/17/2025: 4-1 CIN (Favorite: Guardians, Spread: -1.5, Total: 10, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/16/2025: 5-4 CIN (Favorite: Guardians, Spread: -1.5, Total: 9.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 9/25/2024: 5-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 9/24/2024: 6-1 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -196, Underdog Moneyline: +164)
• 6/12/2024: 4-2 CIN (Favorite: Reds, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/11/2024: 5-3 CLE (Favorite: Reds, Spread: -1.5, Total: 9, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 9/27/2023: 4-3 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 9/26/2023: 11-7 CIN (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -124, Underdog Moneyline: +106)

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