Guardians vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 27

Odds updated as of 6:11 p.m.

The MLB slate on Friday includes the Cleveland Guardians taking on the Houston Astros.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Guardians vs Astros Game Info

• Cleveland Guardians (92-67) vs. Houston Astros (86-73)
• Date: Friday, September 27, 2024
• Time: 7:10 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: MLB Network

Guardians vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-120) | HOU: (+102)
• Spread: CLE: +1.5 (-194) | HOU: -1.5 (+160)
• Total: 8 -- Over: (-105) | Under: (-115)

Guardians vs Astros Probable Starting Pitchers

Probable Pitchers: Joey Cantillo (Guardians) - 2-3, 4.63 ERA vs Ronel Blanco (Astros) - 12-6, 2.88 ERA

The Guardians will look to Joey Cantillo (2-3) against the Astros and Ronel Blanco (12-6). Cantillo's team is 4-3-0 against the spread this season in his starts. Cantillo and his team have won each of the three games he's started as the moneyline favorite. The Astros are 17-11-0 against the spread when Blanco starts. The Astros are 5-3 in Blanco's eight starts this season that they were the underdog on the moneyline.

Guardians vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (52.2%)

Guardians vs Astros Moneyline

• Looking at the moneyline for Guardians-Astros, Cleveland is the favorite at -120, and Houston is +102 playing on the road.

Guardians vs Astros Spread

• The Astros are 1.5-run favorites against the spread for this matchup with the Guardians. The Astros are +160 to cover, while the Guardians are -194 to cover as a 1.5-run underdog on the runline.

Guardians vs Astros Over/Under

• The over/under for Guardians-Astros on Sept. 27 is 8. The over is -105, and the under is -115.

Bet on Cleveland Guardians vs. Houston Astros on FanDuel today!

Guardians vs Astros Betting Trends

• The Guardians have been favorites in 95 games this season and have come away with the win 63 times (66.3%) in those contests.
• This season Cleveland has been victorious 55 times in 78 chances when named as a favorite of at least -120 on the moneyline.
• The Guardians and their opponents have gone over the total this season in 70 of their 157 opportunities.
• In 157 games with a line this season, the Guardians have a mark of 85-72-0 against the spread.
• The Astros have won 19 of the 41 games they were the moneyline underdog this season (46.3%).
• When it has played as a moneyline underdog with odds of +102 or longer, Houston has a 10-10 record (winning 50% of its games).
• The Astros have played in 159 games with a set over/under, and have combined with opponents to go over the total 65 times (65-88-6).
• The Astros have covered 49.1% of their games this season, going 78-81-0 ATS.

Guardians Player Leaders

• Jose Ramirez leads Cleveland in slugging percentage (.533) and total hits (171) this season. He's batting .279 with an on-base percentage of .334.
• Among all qualified batters, he ranks 26th in batting average, his on-base percentage ranks 44th, and he is 11th in slugging.
• Ramirez hopes to build on a two-game hitting streak in this matchup. During his last five outings he is batting .500 with three doubles, a triple, three home runs and eight RBI.
• Josh Naylor is batting .243 with 27 doubles, 31 home runs and 57 walks, while slugging .459 with an on-base percentage of .319.
• He is 94th in batting average, 81st in on-base percentage and 39th in slugging among qualifying hitters.
• Naylor brings a two-game streak with at least one hit into this one. In his last five games he is hitting .188 with a double, two walks and three RBI.
• Steven Kwan leads Cleveland with an OBP of .365 this season while batting .292 with 51 walks and 83 runs scored.
• Kwan takes a five-game hitting streak into this game. In his last five games he is batting .412 with a home run, six walks and an RBI.
• Andres Gimenez is batting .253 with a .300 OBP and 63 RBI for Cleveland this season.

Astros Player Leaders

• Yordan Alvarez has racked up 170 hits with a .392 on-base percentage, leading the Astros in both categories. He's batting .308 and slugging .567.
• Including all qualified hitters in the majors, he ranks sixth in batting average, fourth in on-base percentage and fifth in slugging percentage.
• Jose Altuve paces his team with a .436 slugging percentage. He has a batting average of .293 with an on-base percentage of .349.
• He is currently 12th in batting average, 26th in on-base percentage and 58th in slugging percentage among all qualified hitters.
• Alex Bregman is batting .256 with 28 doubles, two triples, 26 home runs and 44 walks.
• Yainer Diaz is batting .299 with 29 doubles, three triples, 16 home runs and 23 walks.

Guardians vs Astros Head to Head

• 5/2/2024: 8-2 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 5/1/2024: 3-2 CLE (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 4/30/2024: 10-9 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 8/2/2023: 3-2 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 8/1/2023: 2-0 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 7/31/2023: 7-3 HOU (Favorite: Astros, Spread: -1.5, Total: 9.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 6/11/2023: 5-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 6/10/2023: 6-4 HOU (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 6/9/2023: 10-9 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -110, Underdog Moneyline: -106)

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