Cubs vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for July 6

Odds updated as of 5:11 p.m.

The Chicago Cubs are among the MLB teams playing on Sunday, versus the St. Louis Cardinals.

We've got you covered, in terms of the vital info regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Cubs vs Cardinals Game Info

• Chicago Cubs (53-36) vs. St. Louis Cardinals (48-42)
• Date: Sunday, July 6, 2025
• Time: 6:10 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: ESPN

Cubs vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-215) | STL: (+180)
• Spread: CHC: -1.5 (-104) | STL: +1.5 (-115)
• Total: 7 -- Over: (-118) | Under: (-104)

Cubs vs Cardinals Probable Starting Pitchers

Probable Pitchers: Matthew Boyd (Cubs) - 8-3, 2.65 ERA vs Erick Fedde (Cardinals) - 3-8, 4.56 ERA

This contest's pitching matchup is set, as the Cubs will send Matthew Boyd (8-3) to the mound, while Erick Fedde (3-8) will answer the bell for the Cardinals. Boyd and his team are 7-10-0 ATS this season when he starts. Boyd's team is 9-3 this season when he starts and they are the moneyline favorite. The Cardinals have an 8-8-0 ATS record in Fedde's 16 starts that had a set spread. The Cardinals have a 3-8 record in Fedde's 11 starts this season when they were the underdog on the moneyline.

Cubs vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (63.1%)

Cubs vs Cardinals Moneyline

• Looking at the moneyline for Cardinals-Cubs, St. Louis is the underdog at +180, and Chicago is -215 playing at home.

Cubs vs Cardinals Spread

• The Cardinals are +1.5 on the run line against the Cubs. The Cardinals are -115 to cover, and the Cubs are -104.

Cubs vs Cardinals Over/Under

• The Cubs-Cardinals contest on July 6 has been given an over/under of 7 runs. The over is set at -118 and the under at -104.

Bet on Chicago Cubs vs. St. Louis Cardinals on FanDuel today!

Cubs vs Cardinals Betting Trends

• The Cubs have been favorites in 58 games this season and have come away with the win 41 times (70.7%) in those contests.
• Chicago has a record of 9-1 in contests when bookmakers favor them by -215 or more on the moneyline.
• Contests with the Cubs have gone over the total set by sportsbooks in 47 of 87 chances this season.
• The Cubs have posted a record of 43-44-0 against the spread this season.
• The Cardinals have won 52% of the games this season they were the moneyline underdog (26-24).
• St. Louis has not yet played a game with moneyline odds of +180 or longer.
• The Cardinals have had an over/under set by bookmakers 89 times, and have combined with opponents to go over the total in 46 of those games (46-40-3).
• The Cardinals have collected a 49-40-0 record ATS this season (covering 55.1% of the time).

Cubs Player Leaders

• Kyle Tucker has an OPS of .901, fueled by an OBP of .386 to go with a slugging percentage of .515. He has a .283 batting average, as well.
• Among qualifying batters in MLB, his batting average ranks 35th, his on-base percentage ranks seventh, and he is 17th in slugging.
• Pete Crow-Armstrong has 20 doubles, four triples, 23 home runs and 17 walks. He's batting .270 and slugging .552 with an on-base percentage of .308.
• His batting average ranks 53rd among qualified players, his on-base percentage 115th, and his slugging percentage ninth.
• Seiya Suzuki has 89 hits this season and has a slash line of .261/.318/.551.
• Suzuki heads into this matchup with five games in a row with at least one hit. During his last five outings he is hitting .316 with two doubles, two home runs, three walks and six RBIs.
• Michael Busch leads Chicago with 81 hits, batting .293 this season with 35 extra-base hits.
• Busch enters this game on a two-game hitting streak. In his last five games he is hitting .550 with a double, four home runs, a walk and seven RBIs.

Cardinals Player Leaders

• Brendan Donovan has a team-high OBP (.367) and slugging percentage (.431). He's batting .296.
• Including all qualified players in MLB, he ranks 13th in batting average, 25th in on-base percentage and 74th in slugging percentage.
• Donovan takes a four-game hitting streak into this game. In his last five games he is hitting .278 with a double, a home run, three walks and an RBI.
• Nolan Arenado is batting .244 with 13 doubles, a triple, 10 home runs and 24 walks. He's slugging .391 with an on-base percentage of .304.
• His batting average ranks 113th among all qualified players, his on-base percentage ranks 118th, and he is 111th in slugging.
• Alec Burleson has racked up 78 hits, a team-high for the Cardinals.
• Lars Nootbaar is hitting .227 with 13 doubles, 11 home runs and 46 walks.

Cubs vs Cardinals Head to Head

• 7/5/2025: 8-6 STL (Favorite: Cubs, Spread: -1.5, Total: 11, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 7/4/2025: 11-3 CHC (Favorite: Cubs, Spread: -1.5, Total: 9.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 6/26/2025: 3-0 CHC (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 6/25/2025: 8-0 CHC (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 6/24/2025: 8-7 STL (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/23/2025: 8-2 STL (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/4/2024: 6-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 8/3/2024: 5-4 STL (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/2/2024: 6-3 CHC (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/1/2024: 5-4 CHC (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)

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