Guardians vs Angels Prediction, Odds, Moneyline, Spread & Over/Under for May 13

Odds updated as of 1:11 p.m.

The Cleveland Guardians are among the MLB teams in action on Wednesday, versus the Los Angeles Angels.

All the information you need to make smart bets on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Guardians vs Angels Game Info

• Cleveland Guardians (23-21) vs. Los Angeles Angels (16-27)
• Date: Wednesday, May 13, 2026
• Time: 1:10 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: CleGuardians.TV and ABTV

Guardians vs Angels Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-156) | LAA: (+132)
• Spread: CLE: -1.5 (+142) | LAA: +1.5 (-172)
• Total: 7 -- Over: (-102) | Under: (-120)

Guardians vs Angels Probable Starting Pitchers

Probable Pitchers: Parker Messick (Guardians) - 4-1, 2.30 ERA vs Reid Detmers (Angels) - 1-3, 4.33 ERA

The probable starters are Parker Messick (4-1) for the Guardians and Reid Detmers (1-3) for the Angels. When Messick starts, his team is 6-2-0 against the spread this season. Messick's team has been victorious in 60% of the games he's started as the moneyline favorite with a record of 3-2. The Angels have a 2-6-0 record against the spread in Detmers' starts. The Angels are 2-6 in Detmers' eight starts this season that they were the underdog on the moneyline.

Guardians vs Angels Moneyline

• The Guardians vs Angels moneyline has Cleveland as a -156 favorite, while Los Angeles is a +132 underdog on the road.

Guardians vs Angels Spread

• The Angels are at +1.5 on the runline against the Guardians. The Angels are -172 to cover the spread, and the Guardians are +142.

Guardians vs Angels Over/Under

• The over/under for Guardians-Angels on May 13 is 7. The over is -102, and the under is -120.

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Guardians vs Angels Betting Trends

• The Guardians have been favorites in 21 games this season and have come away with the win 11 times (52.4%) in those contests.
• Cleveland has a record of 1-2 in contests when bookmakers favor them by -156 or more on the moneyline.
• Contests with the Guardians have gone over the total set by bookmakers in 22 of 42 chances this season.
• The Guardians have posted a record of 22-20-0 against the spread this season.
• The Angels have an 11-20 record in games they were the underdog on the moneyline (winning 35.5% of those games).
• Los Angeles has a 7-8 record (winning 46.7% of its games) when playing as a moneyline underdog of +132 or longer.
• The Angels have played in 42 games with an over/under set, and have combined with their opponents to go over the total 19 times (19-23-0).
• The Angels have gone 21-21-0 ATS this season.

Guardians Player Leaders

• Jose Ramirez is hitting .210 with eight doubles, six home runs and 31 walks. He has an on-base percentage of .337 and a slugging percentage of .370.
• Among qualifying hitters in MLB, he is 147th in batting average, 79th in on-base percentage, and 117th in slugging.
• Chase DeLauter leads Cleveland with 40 hits and an OBP of .373, plus a team-best slugging percentage of .500. He's batting .286.
• He is 35th in batting average, 32nd in on-base percentage and 29th in slugging in the majors.
• Brayan Rocchio is batting .281 with a .381 slugging percentage and 22 RBI this year.
• Rocchio takes a three-game hitting streak into this game. In his last five games he is hitting .412 with a double, a walk and three RBIs.
• Angel Martinez is batting .260 with a .301 OBP and 18 RBI for Cleveland this season.
• Martinez brings a two-game hitting streak into this matchup. During his last five outings he is hitting .200 with a home run, a walk and two RBIs.

Angels Player Leaders

• Mike Trout has put up a team-best OBP (.419), and leads the Angels in hits (38). He's batting .255 and slugging.
• Including all qualified hitters, he ranks 80th in batting average, while his on-base percentage is third and he is 21st in slugging.
• Zach Neto is hitting .216 with nine doubles, a triple, six home runs and 25 walks. He's slugging .386 with an on-base percentage of .322.
• He is 135th in batting average, 102nd in on-base percentage and 99th in slugging percentage in the big leagues.
• Jo Adell has a .413 slugging percentage, which leads the Angels.
• Nolan Schanuel is batting .261 with 10 doubles, three home runs and 11 walks.

Guardians vs Angels Head to Head

• 5/12/2026: 3-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 5/11/2026: 7-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 6/1/2025: 4-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 5/31/2025: 7-5 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 5/30/2025: 4-1 LAA (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/6/2025: 6-2 LAA (Favorite: Guardians, Spread: -1.5, Total: 9.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/5/2025: 10-4 LAA (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 4/4/2025: 8-6 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/26/2024: 5-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/25/2024: 4-3 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -144, Underdog Moneyline: +122)

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