Guardians vs Angels Prediction, Odds, Moneyline, Spread & Over/Under for May 13

Odds updated as of 7:11 p.m.

The Cleveland Guardians versus the Los Angeles Angels is on the MLB schedule for Wednesday.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Guardians vs Angels Game Info

• Cleveland Guardians (22-21) vs. Los Angeles Angels (16-26)
• Date: Wednesday, May 13, 2026
• Time: 1:10 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: CleGuardians.TV and ABTV

Guardians vs Angels Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-142) | LAA: (+120)
• Spread: CLE: -1.5 (+155) | LAA: +1.5 (-188)
• Total: 7 -- Over: (-105) | Under: (-115)

Guardians vs Angels Probable Starting Pitchers

Probable Pitchers: Parker Messick (Guardians) - 4-1, 2.30 ERA vs Reid Detmers (Angels) - 1-3, 4.33 ERA

The Guardians will give the ball to Parker Messick (4-1, 2.30 ERA), who is eyeing win No. 5 on the season, and the Angels will counter with Reid Detmers (1-3, 4.33 ERA). Messick's team is 6-2-0 against the spread this season in his starts. Messick's team has a record of 3-2 this season when he starts and they are the favorite on the moneyline. When Detmers starts, the Angels are 2-6-0 against the spread. The Angels have a 2-6 record in Detmers' eight starts this season when they were the underdog on the moneyline.

Guardians vs Angels Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Guardians win (54.7%)

Guardians vs Angels Moneyline

• Los Angeles is the underdog, +120 on the moneyline, while Cleveland is a -142 favorite at home.

Guardians vs Angels Spread

• The Angels are +1.5 on the run line against the Guardians. The Angels are -188 to cover, and the Guardians are +155.

Guardians vs Angels Over/Under

• The Guardians-Angels game on May 13 has been given an over/under of 7 runs. The over is set at -105 and the under at -115.

Bet on Cleveland Guardians vs. Los Angeles Angels on FanDuel today!

Guardians vs Angels Betting Trends

• The Guardians have come away with 10 wins in the 20 contests they have been listed as the favorites in this season.
• This season Cleveland has come away with a win three times in five chances when named as a favorite of at least -142 on the moneyline.
• Contests with the Guardians have gone over the total set by sportsbooks in 22 of 41 chances this season.
• In 41 games with a line this season, the Guardians have a mark of 22-19-0 against the spread.
• The Angels are 11-19 in games they were the underdog on the moneyline (winning 36.7% of those games).
• When it has played as a moneyline underdog with odds of +120 or longer, Los Angeles has an 8-10 record (winning 44.4% of its games).
• In the 41 games bookmakers have set an over/under for the Angels, they have combined with opponents to go over the total 19 times (19-22-0).
• The Angels have collected a 20-21-0 record against the spread this season.

Guardians Player Leaders

• Jose Ramirez is batting .215 with eight doubles, six home runs and 31 walks. He has an on-base percentage of .344 and a slugging percentage of .380.
• Among qualified hitters in baseball, his batting average ranks 138th, his on-base percentage ranks 69th, and he is 108th in slugging.
• Chase DeLauter has 40 hits and an OBP of .376 to go with a slugging percentage of .511. All three of those stats rank first among Cleveland hitters this season. He's batting .292.
• Among qualifying batters, he is 29th in batting average, 29th in on-base percentage and 24th in slugging percentage.
• Brayan Rocchio has 38 hits this season and has a slash line of .277/.357/.380.
• Rocchio enters this matchup with two games in a row with at least one hit. In his last five games he is batting .421 with a double, two walks and two RBIs.
• Steven Kwan is batting .204 with a .307 OBP and nine RBI for Cleveland this season.

Angels Player Leaders

• Mike Trout has a team-best OBP (.414), while pacing the Angels in hits (36). He's batting .248 and slugging.
• Including all the qualifying hitters in MLB, he is 90th in batting average, sixth in on-base percentage and 27th in slugging percentage.
• Zach Neto has nine doubles, a triple, six home runs and 24 walks while batting .222. He's slugging .395 with an on-base percentage of .325.
• He is currently 129th in batting average, 100th in on-base percentage and 92nd in slugging percentage among all qualified hitters.
• Nolan Schanuel is hitting .257 with 10 doubles, three home runs and 11 walks.
• Jorge Soler has six doubles, eight home runs and 18 walks while batting .226.

Guardians vs Angels Head to Head

• 5/11/2026: 7-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 6/1/2025: 4-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 5/31/2025: 7-5 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 5/30/2025: 4-1 LAA (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/6/2025: 6-2 LAA (Favorite: Guardians, Spread: -1.5, Total: 9.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/5/2025: 10-4 LAA (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 4/4/2025: 8-6 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/26/2024: 5-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/25/2024: 4-3 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 5/24/2024: 10-4 CLE (Favorite: Angels, Spread: -1.5, Total: 7.5, Favorite Moneyline: -108, Underdog Moneyline: -108)

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