Giants vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for June 29

Odds updated as of 4:13 a.m.

In MLB action on Sunday, the San Francisco Giants take on the Chicago White Sox.

All the information you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Giants vs White Sox Game Info

• San Francisco Giants (45-38) vs. Chicago White Sox (27-56)
• Date: Sunday, June 29, 2025
• Time: 2:10 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and NBCS-BA

Giants vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-146) | CHW: (+124)
• Spread: SF: -1.5 (+112) | CHW: +1.5 (-134)
• Total: 8.5 -- Over: (-110) | Under: (-110)

Giants vs White Sox Probable Starting Pitchers

Probable Pitchers: Justin Verlander (Giants) - 0-5, 4.67 ERA vs Jonathan Cannon (White Sox) - 2-7, 4.66 ERA

This contest's pitching matchup is set, as the Giants will send Justin Verlander (0-5) to the mound, while Jonathan Cannon (2-7) will take the ball for the White Sox. Verlander and his team are 3-9-0 ATS this season when he starts. Verlander's team has a record of 3-4 this season when he starts and they are the favorite on the moneyline. The White Sox have a 3-7-0 record against the spread in Cannon's starts. The White Sox are 1-9 in Cannon's 10 starts this season that they were the underdog on the moneyline.

Giants vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Giants win (57.1%)

Giants vs White Sox Moneyline

• The moneyline numbers for Giants vs. White Sox reveal San Francisco as the favorite (-146) and Chicago as the underdog (+124) despite being the home team.

Giants vs White Sox Spread

• The Giants are at the White Sox and are favored by 1.5 runs on the spread. The Giants are +112 to cover the runline, with the White Sox being -134.

Giants vs White Sox Over/Under

• Giants versus White Sox, on June 29, has an over/under of 8.5, with the over being -110 and the under -110.

Bet on San Francisco Giants vs. Chicago White Sox on FanDuel today!

Giants vs White Sox Betting Trends

• The Giants have been favorites in 56 games this season and have come away with the win 31 times (55.4%) in those contests.
• San Francisco has a record of 17-14 when favored by -146 or more this year.
• The Giants and their opponents have gone over the total this season in 37 of their 83 opportunities.
• The Giants have an against the spread mark of 36-47-0 in 83 games with a line this season.
• The White Sox have a 25-54 record in games they were the underdog on the moneyline (winning 31.6% of those games).
• In games it has played as a moneyline underdog with odds of +124 or longer, Chicago has a record of 21-44 (32.3%).
• The White Sox have played in 80 games with an over/under set, and have combined with their opponents to go over the total 36 times (36-40-4).
• The White Sox have a 44-36-0 record ATS this season (covering 55% of the time).

Giants Player Leaders

• Rafael Devers leads San Francisco in OBP (.392) and total hits (84) this season. He's batting .267 batting average while slugging .492.
• Among qualifying batters in MLB, he is 61st in batting average, sixth in on-base percentage, and 26th in slugging.
• Jung Hoo Lee has 17 doubles, six triples, six home runs and 29 walks. He's batting .246 and slugging .402 with an on-base percentage of .315.
• Among qualifying hitters, he ranks 107th in batting average, 106th in on-base percentage and 102nd in slugging percentage.
• Heliot Ramos has an OPS of .821, fueled by an OBP of .358 and a team-best slugging percentage of .463 this season.
• Wilmer Flores is batting .243 with a .315 OBP and 55 RBI for San Francisco this season.

White Sox Player Leaders

• Miguel Vargas has accumulated an on-base percentage of .312, a slugging percentage of .415, and has 68 hits, all club-bests for the White Sox (while batting .231).
• Including all qualified hitters in the big leagues, his batting average places him 132nd, his on-base percentage is 111th, and he is 90th in slugging.
• Andrew Benintendi is batting .237 with nine doubles, two triples, 10 home runs and 17 walks. He's slugging .455 with an on-base percentage of .300.
• Chase Meidroth is hitting .260 with five doubles, two home runs and 28 walks.
• Luis Robert is hitting .185 with eight doubles, eight home runs and 29 walks.

Giants vs White Sox Head to Head

• 6/28/2025: 1-0 CHW (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 6/27/2025: 3-1 SF (Favorite: Giants, Spread: -1.5, Total: 9, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 8/21/2024: 6-2 CHW (Favorite: Giants, Spread: -1.5, Total: 6.5, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 8/20/2024: 4-1 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -255, Underdog Moneyline: +210)
• 8/19/2024: 5-3 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -245, Underdog Moneyline: +200)
• 4/6/2023: 16-6 SF (Favorite: White Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 4/5/2023: 7-3 CHW (Favorite: White Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 4/3/2023: 12-3 SF (Favorite: White Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 7/3/2022: 13-4 CHW (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 7/2/2022: 5-3 CHW (Favorite: Giants, Spread: -1.5, Total: 7, Favorite Moneyline: -148, Underdog Moneyline: +126)

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