Giants vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for June 19

Odds updated as of 4:12 a.m.

The Thursday schedule in MLB includes a matchup between the San Francisco Giants and the Cleveland Guardians.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important info regarding this matchup.

Giants vs Guardians Game Info

• San Francisco Giants (41-33) vs. Cleveland Guardians (37-35)
• Date: Thursday, June 19, 2025
• Time: 4:05 p.m. ET
• Venue: Oracle Park -- San Francisco, California
• Coverage: NBCS-BA and CLEG

Giants vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-136) | CLE: (+116)
• Spread: SF: -1.5 (+152) | CLE: +1.5 (-184)
• Total: 8 -- Over: (-120) | Under: (-102)

Giants vs Guardians Probable Starting Pitchers

Probable Pitchers: Logan Webb (Giants) - 6-5, 2.58 ERA vs Gavin Williams (Guardians) - 5-3, 3.89 ERA

The probable pitchers are Logan Webb (6-5) for the Giants and Gavin Williams (5-3) for the Guardians. Webb's team is 7-8-0 against the spread in his starts this season. Webb's team has been victorious in 46.2% of the games he's started as the moneyline favorite with a record of 6-7. The Guardians are 7-7-0 ATS in Williams' 14 starts with a set spread. The Guardians have a 4-5 record in Williams' nine starts this season when they were the underdog on the moneyline.

Giants vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Giants win (64.7%)

Giants vs Guardians Moneyline

• San Francisco is a -136 favorite on the moneyline, while Cleveland is a +116 underdog on the road.

Giants vs Guardians Spread

• The Guardians are +1.5 on the run line against the Giants. The Guardians are -184 to cover, and the Giants are +152.

Giants vs Guardians Over/Under

• The over/under for Giants-Guardians on June 19 is 8. The over is -120, and the under is -102.

Bet on San Francisco Giants vs. Cleveland Guardians on FanDuel today!

Giants vs Guardians Betting Trends

• The Giants have come away with 27 wins in the 47 contests they have been listed as the favorites in this season.
• San Francisco has a record of 19-12 in contests when sportsbooks favor them by -136 or more on the moneyline.
• The Giants' games have gone over the total in 33 of their 74 opportunities.
• The Giants have posted a record of 34-40-0 against the spread this season.
• The Guardians are 21-25 in games they were listed as the moneyline underdog (winning 45.7% of those games).
• Cleveland is 8-10 (winning 44.4% of its games) when playing as a moneyline underdog of +116 or longer.
• In the 70 games bookmakers have set an over/under for the Guardians, they have combined with opponents to go over the total 31 times (31-36-3).
• The Guardians have gone 35-35-0 ATS this season.

Giants Player Leaders

• Rafael Devers leads San Francisco in OBP (.399) and total hits (76) this season. He's batting .271 batting average while slugging .500.
• Among all qualifying hitters in the majors, his batting average ranks 52nd, his on-base percentage ranks sixth, and he is 20th in slugging.
• Jung Hoo Lee is batting .261 with 17 doubles, five triples, six home runs and 25 walks, while slugging .424 with an on-base percentage of .324.
• He ranks 68th in batting average, 86th in on-base percentage and 81st in slugging among qualified hitters.
• Heliot Ramos has hit 12 homers with a team-high .469 SLG this season.
• Wilmer Flores has 11 home runs, 51 RBI and a batting average of .253 this season.

Guardians Player Leaders

• Jose Ramirez has accumulated an on-base percentage of .382, a slugging percentage of .532, and has 84 hits, all club-highs for the Guardians (while batting .319).
• Including all qualified hitters in the majors, he is eighth in batting average, 16th in on-base percentage and 11th in slugging percentage.
• Steven Kwan is hitting .293 with 14 doubles, six home runs and 25 walks. He's slugging .414 with an on-base percentage of .358.
• He is 20th in batting average, 36th in on-base percentage and 88th in slugging percentage in MLB.
• Carlos Santana has six doubles, eight home runs and 33 walks while hitting .245.
• Kyle Manzardo is hitting .212 with 10 doubles, two triples, 11 home runs and 23 walks.

Giants vs Guardians Head to Head

• 6/18/2025: 4-2 CLE (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 6/17/2025: 3-2 CLE (Favorite: Giants, Spread: -1.5, Total: 7, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 7/7/2024: 5-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/6/2024: 5-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 7/5/2024: 4-2 SF (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 9/13/2023: 6-5 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 9/12/2023: 3-1 CLE (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 9/11/2023: 5-4 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)

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