Giants vs Brewers Prediction, Odds, Moneyline, Spread & Over/Under for April 23

Odds updated as of 9:11 p.m.

MLB action on Wednesday includes the San Francisco Giants playing the Milwaukee Brewers.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's everything you need to know.

Giants vs Brewers Game Info

• San Francisco Giants (15-9) vs. Milwaukee Brewers (13-11)
• Date: Wednesday, April 23, 2025
• Time: 9:45 p.m. ET
• Venue: Oracle Park -- San Francisco, California
• Coverage: NBCS-BA+ and FDSWI

Giants vs Brewers Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-134) | MIL: (+116)
• Spread: SF: -1.5 (+164) | MIL: +1.5 (-200)
• Total: 7.5 -- Over: (-105) | Under: (-115)

Giants vs Brewers Probable Starting Pitchers

Probable Pitchers: Logan Webb (Giants) - 2-1, 2.40 ERA vs Freddy Peralta (Brewers) - 2-1, 1.91 ERA

This contest's pitching matchup is set, as the Giants will send Logan Webb (2-1) to the mound, while Freddy Peralta (2-1) will take the ball for the Brewers. Webb and his team have a record of 3-2-0 against the spread when he starts. Webb's team has been victorious in 50% of the games he's started as the moneyline favorite with a record of 2-2. When Peralta starts, the Brewers have gone 3-2-0 against the spread. The Brewers were named the moneyline underdog for two Peralta starts this season -- they lost both.

Giants vs Brewers Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Giants win (55.9%)

Giants vs Brewers Moneyline

• Looking at the moneyline for Brewers-Giants, Milwaukee is the underdog at +116, and San Francisco is -134 playing at home.

Giants vs Brewers Spread

• The Brewers are at the Giants, and are +1.5 on the runline. The Brewers are +164 to cover the spread, and the Giants are -200.

Giants vs Brewers Over/Under

• A total of 7.5 runs has been set for the Giants-Brewers contest on April 23, with the over available at -105 and the under at -115.

Bet on San Francisco Giants vs. Milwaukee Brewers on FanDuel today!

Giants vs Brewers Betting Trends

• The Giants have been chosen as favorites in 13 games this year and have walked away with the win nine times (69.2%) in those games.
• This year San Francisco has won five of eight games when listed as at least -134 on the moneyline.
• The Giants and their opponents have gone over the total this season in 15 of their 24 opportunities.
• The Giants have posted a record of 13-11-0 against the spread this season.
• The Brewers have put together a 3-7 record in games they were listed as the moneyline underdog (winning 30% of those games).
• Milwaukee has a 2-5 record (winning just 28.6% of its games) when playing as a moneyline underdog of +116 or longer.
• The Brewers have played in 24 games with a set over/under, and have combined with their opponents to go over the total 10 times (10-14-0).
• The Brewers are 13-11-0 ATS this season.

Giants Player Leaders

• Jung Hoo Lee leads San Francisco in slugging percentage (.573) and total hits (28) this season. He's batting .315 with an on-base percentage of .374.
• Among all qualified batters in the majors, he ranks 22nd in batting average, 35th in on-base percentage, and 14th in slugging.
• Wilmer Flores is batting .247 with seven home runs and six walks. He's slugging .494 with an on-base percentage of .304.
• His batting average ranks 82nd among qualified players, his on-base percentage 106th, and his slugging percentage 38th.
• Flores enters this game looking to extend his two-game hit streak. In his last five games he is hitting .278 with a home run, three walks and two RBI.
• Matt James Chapman has 19 hits this season and has a slash line of .235/.398/.432.
• Mike Yastrzemski leads San Francisco in OBP (.423) this season, fueled by 18 hits.
• Yastrzemski heads into this game on a two-game hitting streak. During his last five outings he is hitting .250 with two doubles, four walks and two RBI.

Brewers Player Leaders

• Brice Turang has a slugging percentage of .442, a team-best for the Brewers. He's batting .337 with an on-base percentage of .375.
• He is ninth in batting average, 34th in on-base percentage and 62nd in slugging percentage among all qualifying batters in MLB.
• Jackson Chourio leads his team with 27 hits. He has a batting average of .260 while slugging .500 with an on-base percentage of .278.
• His batting average is 73rd among all qualified players, his on-base percentage is 130th, and he is 33rd in slugging.
• Sal Frelick has accumulated a team-best .412 on-base percentage.
• Christian Yelich is hitting .222 with three doubles, five home runs and 13 walks.

Giants vs Brewers Head to Head

• 4/22/2025: 11-3 MIL (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/21/2025: 5-2 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 9/12/2024: 3-0 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 9/11/2024: 13-2 SF (Favorite: Giants, Spread: -1.5, Total: 7, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 9/10/2024: 3-2 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/29/2024: 6-0 MIL (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 8/28/2024: 5-3 MIL (Favorite: Brewers, Spread: -1.5, Total: 8, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 8/27/2024: 5-4 SF (Favorite: Brewers, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/28/2023: 7-5 MIL (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 5/27/2023: 3-1 SF (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)

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