Diamondbacks vs Rays Prediction, Odds, Moneyline, Spread & Over/Under for April 22

Odds updated as of 9:11 p.m.

Tuesday's slate in the MLB includes a matchup between the Arizona Diamondbacks and the Tampa Bay Rays.

We've got you covered, in terms of the vital information regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Diamondbacks vs Rays Game Info

• Arizona Diamondbacks (13-9) vs. Tampa Bay Rays (9-13)
• Date: Tuesday, April 22, 2025
• Time: 9:40 p.m. ET
• Venue: Chase Field -- Phoenix, Arizona
• Coverage: MLB Network, ARID, and FDSSUN

Diamondbacks vs Rays Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: ARI: (-174) | TB: (+146)
• Spread: ARI: -1.5 (+114) | TB: +1.5 (-137)
• Total: 9 -- Over: (-114) | Under: (-106)

Diamondbacks vs Rays Probable Starting Pitchers

Probable Pitchers: Brandon Pfaadt (Diamondbacks) - 3-1, 3.04 ERA vs Zack Littell (Rays) - 0-4, 5.48 ERA

The Diamondbacks will give the nod to Brandon Pfaadt (3-1, 3.04 ERA), who is eyeing win No. 4 on the season, and the Rays will turn to Zack Littell (0-4, 5.48 ERA). Pfaadt and his team are 3-1-0 ATS this season when he starts. Pfaadt's team has been victorious in 75% of the games he's started as the moneyline favorite with a record of 3-1. The Rays have failed to cover all of the four games Littell started that had a spread set by bookmakers. The Rays were named the moneyline underdog for one Littell start this season -- they lost.

Diamondbacks vs Rays Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Diamondbacks win (56.4%)

Diamondbacks vs Rays Moneyline

• Tampa Bay is a +146 underdog on the moneyline, while Arizona is a -174 favorite at home.

Diamondbacks vs Rays Spread

• The Rays are +1.5 on the run line against the Diamondbacks. The Rays are -137 to cover, and the Diamondbacks are +114.

Diamondbacks vs Rays Over/Under

• Diamondbacks versus Rays, on April 22, has an over/under of 9, with the over being -114 and the under -106.

Bet on Arizona Diamondbacks vs. Tampa Bay Rays on FanDuel today!

Diamondbacks vs Rays Betting Trends

• The Diamondbacks have won in 10, or 58.8%, of the 17 contests they have been named as odds-on favorites in this year.
• Arizona has been listed as a favorite of -174 or more on two occasions this season and split those games.
• The Diamondbacks and their opponents have gone over in 10 of their 21 games with a total set by sportsbooks this season.
• The Diamondbacks have an against the spread record of 11-10-0 in 21 games with a line this season.
• The Rays have won 16.7% of the games this season they were the moneyline underdog (1-5).
• Tampa Bay has played as a moneyline underdog of +146 or longer in just one game this season, which it lost.
• The Rays have had an over/under set by oddsmakers 22 times, and have combined with opponents to go over the total in nine of those games (9-11-2).
• The Rays have covered only 36.4% of their games this season, going 8-14-0 against the spread.

Diamondbacks Player Leaders

• Corbin Carroll leads Arizona in slugging percentage (.645) and total hits (30) this season. He's batting .323 with an on-base percentage of .394.
• He is 15th in batting average, 22nd in on-base percentage, and fifth in slugging among all qualified hitters in baseball.
• Josh Naylor has 28 hits this season and a team-best OBP of .406. He's batting .333 and slugging .548.
• Among qualified hitters, his batting average places him 11th, his on-base percentage 15th, and his slugging percentage 18th.
• Geraldo Perdomo has 22 hits this season and has a slash line of .286/.392/.442.
• Pavin Smith has been key for Arizona with 21 hits, an OBP of .485 plus a slugging percentage of .691.

Rays Player Leaders

• Jonathan Aranda has racked up a team-high OBP (.438) and slugging percentage (.677), while pacing the Rays in hits (22, while batting .355).
• Including all qualifying hitters in the majors, his batting average places him fourth, his on-base percentage is fourth, and he is third in slugging.
• Junior Caminero is hitting .269 with three doubles, five home runs and five walks. He's slugging .500 with an on-base percentage of .310.
• Including all qualifying hitters, his batting average puts him 65th, his on-base percentage ranks 102nd, and he is 35th in slugging.
• Kameron Misner is batting .360 with four doubles, a triple, three home runs and four walks.
• Yandy (Fernandez) Diaz has four doubles, three home runs and six walks while batting .222.

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