Diamondbacks vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 4

Odds updated as of 3:11 p.m.

The MLB slate on Tuesday includes the Arizona Diamondbacks facing the San Diego Padres.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's everything you need to know.

Diamondbacks vs Padres Game Info

• Arizona Diamondbacks (60-53) vs. San Diego Padres (58-55)
• Date: Tuesday, August 4, 2026
• Time: 9:40 p.m. ET
• Venue: Chase Field -- Phoenix, Arizona
• Coverage: Dbacks.TV and Padres.TV

Diamondbacks vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: ARI: (-116) | SD: (+106)
• Spread: ARI: +1.5 (-205) | SD: -1.5 (+168)
• Total: 9 -- Over: (-105) | Under: (-115)

Diamondbacks vs Padres Probable Starting Pitchers

Probable Pitchers: Eduardo Rodríguez (Diamondbacks) - 10-3, 2.48 ERA vs Randy Vasquez (Padres) - 6-6, 4.45 ERA

The Diamondbacks will give the nod to Eduardo Rodriguez (10-3, 2.48 ERA), who is eyeing win No. 11 on the season, and the Padres will counter with Randy Vasquez (6-6, 4.45 ERA). Rodriguez and his team are 14-8-0 ATS this season when he starts. Rodriguez's team is 8-2 this season when he starts and they are the moneyline favorite. When Vasquez starts, the Padres are 11-6-0 against the spread. The Padres have a 4-4 record in Vasquez's eight starts this season when they were the underdog on the moneyline.

Diamondbacks vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Diamondbacks win (54.7%)

Diamondbacks vs Padres Moneyline

• San Diego is a +106 underdog on the moneyline, while Arizona is a -116 favorite at home.

Diamondbacks vs Padres Spread

• The Padres are 1.5-run favorites against the spread for this matchup with the Diamondbacks. The Padres are +168 to cover, while the Diamondbacks are -205 to cover as a 1.5-run underdog on the runline.

Diamondbacks vs Padres Over/Under

• The Diamondbacks-Padres contest on Aug. 4 has been given an over/under of 9 runs. The over is set at -105 and the under at -115.

Bet on Arizona Diamondbacks vs. San Diego Padres on FanDuel today!

Diamondbacks vs Padres Betting Trends

• The Diamondbacks have won in 29, or 61.7%, of the 47 contests they have been named as odds-on favorites in this year.
• Arizona has a record of 24-15 when favored by -116 or more this year.
• The Diamondbacks and their opponents have gone over in 47 of their 112 games with a total set by sportsbooks this season.
• In 112 games with a line this season, the Diamondbacks have a mark of 60-52-0 against the spread.
• The Padres have been the underdog on the moneyline 62 total times this season. They've gone 29-33 in those games.
• San Diego is 19-26 (winning 42.2% of its games) when it has played as a moneyline underdog of +106 or longer.
• The Padres have played in 113 games with a set over/under, and have combined with their opponents to go over the total 51 times (51-61-1).
• The Padres have covered 54.9% of their games this season, going 62-51-0 against the spread.

Diamondbacks Player Leaders

• Ketel Marte leads Arizona in slugging percentage (.444) thanks to 44 extra-base hits. He has a .249 batting average and an on-base percentage of .307.
• Among the qualifying batters in MLB, his batting average ranks 85th, his on-base percentage ranks 119th, and he is 60th in slugging.
• Corbin Carroll has 100 hits, which leads Arizona batters this season. He's batting .244 with 50 extra-base hits. He's also slugging .473 with an on-base percentage of .340.
• He is 96th in batting average, 62nd in on-base percentage and 36th in slugging among qualifying hitters.
• Geraldo Perdomo is batting .242 with a .369 slugging percentage and 41 RBI this year.
• Perdomo heads into this game with four games in a row with at least one hit. During his last five outings he is hitting .450 with a home run, two walks and four RBIs.
• Gabriel Moreno leads Arizona with an OBP of .380 this season while batting .298 with 40 walks and 46 runs scored.

Padres Player Leaders

• Fernando Tatis Jr. has racked up an on-base percentage of .351 and a slugging percentage of .395. Both lead the Padres. He's batting .280.
• Including all qualifying hitters, he is 31st in batting average, while his on-base percentage is 42nd and he is 102nd in slugging.
• Manny Machado's 85 hits lead his team. He has a batting average of .208 while slugging .424 with an on-base percentage of .292.
• He is currently 145th in batting average, 137th in on-base percentage and 75th in slugging percentage among all qualifying hitters.
• Jackson Merrill has 18 doubles, a triple, 16 home runs and 30 walks while batting .237.
• Xander Bogaerts is batting .221 with 10 doubles, nine home runs and 50 walks.

Diamondbacks vs Padres Head to Head

• 8/3/2026: 5-1 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -110, Underdog Moneyline: +100)
• 7/9/2026: 3-1 ARI (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/8/2026: 10-4 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/7/2026: 4-1 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 7/6/2026: 8-0 ARI (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 4/26/2026: 12-7 ARI (Favorite: Padres, Spread: -1.5, Total: 15, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 4/25/2026: 6-4 SD (Favorite: Diamondbacks, Spread: -1.5, Total: 16, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/28/2025: 12-4 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/27/2025: 5-1 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 9/26/2025: 7-4 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -144, Underdog Moneyline: +122)

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