Diamondbacks vs Athletics Prediction, Odds, Moneyline, Spread & Over/Under for July 22

Odds updated as of 3:11 p.m.

In MLB action on Wednesday, the Arizona Diamondbacks take on the Athletics.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important info about this game.

Diamondbacks vs Athletics Game Info

• Arizona Diamondbacks (52-49) vs. Athletics (43-58)
• Date: Wednesday, July 22, 2026
• Time: 3:40 p.m. ET
• Venue: Chase Field -- Phoenix, Arizona
• Coverage: Dbacks.TV and NBCS-CA

Diamondbacks vs Athletics Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: ARI: (-134) | OAK: (+116)
• Spread: ARI: -1.5 (+146) | OAK: +1.5 (-176)
• Total: 9.5 -- Over: (-104) | Under: (-118)

Diamondbacks vs Athletics Probable Starting Pitchers

Probable Pitchers: Merrill Kelly (Diamondbacks) - 7-8, 5.20 ERA vs Gage Jump (Athletics) - 3-5, 3.78 ERA

The Diamondbacks will give the nod to Merrill Kelly (7-8) versus the Athletics and Gage Jump (3-5). Kelly's team is 10-7-0 against the spread this season in his starts. Kelly's team has won 33.3% of his starts when they are favored on the moneyline (2-4). The Athletics have gone 6-4-0 ATS in Jump's 10 starts that had a set spread. The Athletics have been the underdog on the moneyline in four of Jump's starts this season, and they went 1-3 in those matchups.

Diamondbacks vs Athletics Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Athletics win (55%)

Diamondbacks vs Athletics Moneyline

• The Diamondbacks vs Athletics moneyline has the Diamondbacks as a -134 favorite, while the Athletics are a +116 underdog on the road.

Diamondbacks vs Athletics Spread

• The Diamondbacks are 1.5-run favorites on the runline against the Athletics. The Diamondbacks are +146 to cover, while the Athletics are -176 to cover.

Diamondbacks vs Athletics Over/Under

• Diamondbacks versus Athletics, on July 22, has an over/under of 9.5, with the over being -104 and the under -118.

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Diamondbacks vs Athletics Betting Trends

• The Diamondbacks have come away with 26 wins in the 43 contests they have been listed as the favorites in this season.
• This season, the Diamondbacks have come away with a win 13 times in 21 chances when named as a favorite of at least -134 or better on the moneyline.
• The Diamondbacks and their opponents have hit the over in 42 of their 100 games with a total this season.
• The Diamondbacks are 54-46-0 against the spread in their 100 games with a line set by sportsbooks this season.
• The Athletics have been the moneyline underdog 64 total times this season. They've finished 27-37 in those games.
• In games they have played as a moneyline underdog with odds of +116 or longer, the Athletics have gone 12-18 (40%).
• The Athletics have played in 101 games with an over/under set, and have combined with their opponents to go over the total 50 times (50-50-1).
• The Athletics are 47-54-0 against the spread this season.

Diamondbacks Player Leaders

• Ketel Marte leads Arizona with a slugging percentage of .458, fueled by 40 extra-base hits. He has a .256 batting average and an on-base percentage of .311.
• Among qualified hitters in MLB, his batting average ranks 76th, his on-base percentage ranks 107th, and he is 52nd in slugging.
• Corbin Carroll has 90 hits, which is tops among Arizona batters this season. He's batting .249 with 44 extra-base hits. He's also slugging .476 with an on-base percentage of .342.
• Among all qualifying hitters, he is 86th in batting average, 60th in on-base percentage and 31st in slugging percentage.
• Carroll takes a two-game streak with at least one hit into this matchup. In his last five games he is batting .150 with a double, a home run, a walk and two RBIs.
• Geraldo Perdomo leads Arizona in OBP (.355) this season, fueled by 82 hits.
• Perdomo enters this game with three games in a row with at least one hit. In his last five games he is batting .222 with a double, a home run, four walks and two RBIs.
• Ildemaro Vargas is batting .258 with a .302 OBP and 48 RBI for Arizona this season.
• Vargas takes a four-game hitting streak into this matchup. During his last five outings he is hitting .294 with a double, a triple, a walk and two RBIs.

Athletics Player Leaders

• Shea Langeliers has a .496 slugging percentage, which leads the Athletics. He's batting .260 with an on-base percentage of .330.
• Including all the qualified hitters in the majors, his batting average places him 61st, his on-base percentage ranks 77th, and he is 25th in slugging.
• Langeliers enters this matchup on a six-game hitting streak. During his last 10 games he is hitting .222 with two doubles, three home runs, five walks and six RBIs.
• Tyler Soderstrom has 21 doubles, two triples, 16 home runs and 46 walks while batting .247. He's slugging .475 with an on-base percentage of .346.
• Including all qualified hitters, his batting average places him 89th, his on-base percentage ranks 56th, and he is 34th in slugging.
• Jacob Wilson is batting .291 with 10 doubles, a triple, seven home runs and 11 walks.
• Carlos Cortes is hitting .280 with 12 doubles, a triple, seven home runs and 22 walks.

Diamondbacks vs Athletics Head to Head

• 7/21/2026: 6-5 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9.5, Favorite Moneyline: -134, Underdog Moneyline: +116)
• 7/20/2026: 5-2 OAK (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 8/3/2025: 6-4 ARI (Favorite: Athletics, Spread: -1.5, Total: 9.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 8/2/2025: 7-2 ARI (Favorite: Athletics, Spread: -1.5, Total: 9.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/1/2025: 5-1 OAK (Favorite: Athletics, Spread: -1.5, Total: 10, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 6/30/2024: 5-1 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -198, Underdog Moneyline: +166)
• 6/29/2024: 3-0 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -198, Underdog Moneyline: +166)
• 6/28/2024: 9-4 OAK (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 5/17/2023: 5-3 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 5/16/2023: 9-8 OAK (Favorite: Diamondbacks, Spread: -1.5, Total: 9.5, Favorite Moneyline: -158, Underdog Moneyline: +134)

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