Diamondbacks vs Athletics Prediction, Odds, Moneyline, Spread & Over/Under for July 21

Odds updated as of 9:13 a.m.

The MLB slate on Tuesday includes the Arizona Diamondbacks taking on the Athletics.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's what you need to know.

Diamondbacks vs Athletics Game Info

• Arizona Diamondbacks (51-49) vs. Athletics (43-57)
• Date: Tuesday, July 21, 2026
• Time: 9:40 p.m. ET
• Venue: Chase Field -- Phoenix, Arizona
• Coverage: Dbacks.TV and NBCS-CA

Diamondbacks vs Athletics Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: ARI: (-134) | OAK: (+116)
• Spread: ARI: -1.5 (+152) | OAK: +1.5 (-184)
• Total: 9.5 -- Over: (-120) | Under: (-102)

Diamondbacks vs Athletics Probable Starting Pitchers

Probable Pitchers: Kohl Drake (Diamondbacks) - 0-0, 0.00 ERA vs Jack Perkins (Athletics) - 2-5, 6.87 ERA

The probable starters are Kohl Drake for the Diamondbacks and Jack Perkins (2-5) for the Athletics. Drake did not pitch as the moneyline favorite last season. The Athletics are 1-5-0 against the spread when Perkins starts. The Athletics were the moneyline underdog for one Perkins start this season -- they lost.

Diamondbacks vs Athletics Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Athletics win (55.1%)

Diamondbacks vs Athletics Moneyline

• The Diamondbacks vs Athletics moneyline has the Diamondbacks as a -134 favorite, while the Athletics are a +116 underdog on the road.

Diamondbacks vs Athletics Spread

• The Diamondbacks are 1.5-run favorites on the runline against the Athletics. The Diamondbacks are +152 to cover, while the Athletics are -184 to cover.

Diamondbacks vs Athletics Over/Under

• A combined run total of 9.5 has been set for Diamondbacks-Athletics on July 21, with the over at -120 and the under at -102.

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Diamondbacks vs Athletics Betting Trends

• The Diamondbacks have been favorites in 42 games this season and have come away with the win 25 times (59.5%) in those contests.
• This year, the Diamondbacks have won 12 of 20 games when listed as at least -134 or better on the moneyline.
• The Diamondbacks and their opponents have hit the over in 41 of their 99 games with a total this season.
• The Diamondbacks have an against the spread mark of 54-45-0 in 99 games with a line this season.
• The Athletics have gone 27-36 in games they were listed as the moneyline underdog (winning 42.9% of those games).
• When playing as a moneyline underdog with odds of +116 or longer, the Athletics have gone 12-18 (40%).
• The Athletics have combined with their opponents to go over the total 49 times this season for a 49-50-1 record against the over/under.
• The Athletics have a 46-54-0 record against the spread this season.

Diamondbacks Player Leaders

• Ketel Marte has an OPS of .773, fueled by an OBP of .312 and a team-best slugging percentage of .461 this season. He has a .258 batting average.
• Among qualifying hitters in the majors, his batting average ranks 70th, his on-base percentage ranks 108th, and he is 49th in slugging.
• Marte has recorded at least one hit in four straight games. During his last five outings he is batting .238 with a home run, a walk and four RBIs.
• Corbin Carroll has 89 hits, which leads Arizona batters this season. He's batting .250 with 44 extra-base hits. He's also slugging .480 with an on-base percentage of .344.
• His batting average ranks 86th among qualified players, his on-base percentage 57th, and his slugging percentage 31st.
• Geraldo Perdomo has 81 hits this season and a team-best OBP of .356.
• Perdomo has logged a hit or more in two straight games. In his last five games he is batting .188 with a home run, five walks and two RBIs.
• Ildemaro Vargas is batting .258 with a .301 OBP and 47 RBI for Arizona this season.
• Vargas takes a three-game hitting streak into this game. During his last five outings he is hitting .278 with a double, a triple and an RBI.

Athletics Player Leaders

• Tyler Soderstrom is batting .247 with 21 doubles, two triples, 16 home runs and 45 walks. He's slugging .478 with an on-base percentage of .345.
• Including all qualifying players, he is 87th in batting average, while his on-base percentage is 55th and he is 32nd in slugging.
• Soderstrom hopes to build on a four-game hitting streak in this matchup. In his last five games he is hitting .300 with two home runs, a walk and five RBIs.
• Shea Langeliers' .490 slugging percentage leads his team. He has a batting average of .260 with an on-base percentage of .329.
• Including all qualified hitters, his batting average places him 64th, his on-base percentage is 79th, and he is 26th in slugging.
• Jacob Wilson has 10 doubles, a triple, six home runs and 11 walks while batting .292.
• Carlos Cortes is hitting .282 with 12 doubles, a triple, seven home runs and 22 walks.

Diamondbacks vs Athletics Head to Head

• 7/20/2026: 5-2 OAK (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 8/3/2025: 6-4 ARI (Favorite: Athletics, Spread: -1.5, Total: 9.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 8/2/2025: 7-2 ARI (Favorite: Athletics, Spread: -1.5, Total: 9.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/1/2025: 5-1 OAK (Favorite: Athletics, Spread: -1.5, Total: 10, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 6/30/2024: 5-1 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -198, Underdog Moneyline: +166)
• 6/29/2024: 3-0 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -198, Underdog Moneyline: +166)
• 6/28/2024: 9-4 OAK (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 5/17/2023: 5-3 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 5/16/2023: 9-8 OAK (Favorite: Diamondbacks, Spread: -1.5, Total: 9.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 5/15/2023: 5-2 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -220, Underdog Moneyline: +184)

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