Cubs vs Tigers Prediction, Odds, Moneyline, Spread & Over/Under for July 22

Odds updated as of 7:12 p.m.

On Wednesday in MLB, the Chicago Cubs are up against the Detroit Tigers.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital info about this matchup.

Cubs vs Tigers Game Info

• Chicago Cubs (57-44) vs. Detroit Tigers (47-54)
• Date: Wednesday, July 22, 2026
• Time: 8:10 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: ESPN

Cubs vs Tigers Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-120) | DET: (+102)
• Spread: CHC: +1.5 (-205) | DET: -1.5 (+168)
• Total: 8 -- Over: (-115) | Under: (-105)

Cubs vs Tigers Probable Starting Pitchers

Probable Pitchers: Colin Rea (Cubs) - 7-6, 4.74 ERA vs Keider Montero (Tigers) - 6-5, 3.22 ERA

The Cubs will give the ball to Colin Rea (7-6, 4.74 ERA), who is eyeing win No. 8 on the season, and the Tigers will turn to Keider Montero (6-5, 3.22 ERA). Rea's team is 5-11-0 against the spread this season in his starts. Rea's team is 4-6 this season when he starts and they are the moneyline favorite. The Tigers are 10-5-0 ATS in Montero's 15 starts with a set spread. The Tigers have a 2-5 record in Montero's seven starts this season when they were the moneyline underdog.

Cubs vs Tigers Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (59.6%)

Cubs vs Tigers Moneyline

• Looking at the moneyline for Tigers-Cubs, Detroit is the underdog at +102, and Chicago is -120 playing at home.

Cubs vs Tigers Spread

• The Tigers are 1.5-run favorites against the spread for this matchup with the Cubs. The Tigers are +168 to cover, while the Cubs are -205 to cover as a 1.5-run underdog on the runline.

Cubs vs Tigers Over/Under

• The Cubs-Tigers contest on July 22 has been given an over/under of 8 runs. The over is set at -115 and the under at -105.

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Cubs vs Tigers Betting Trends

• The Cubs have been favorites in 66 games this season and have come away with the win 38 times (57.6%) in those contests.
• Chicago has a record of 32-24 when favored by -120 or more this year.
• The Cubs' games have gone over the total in 53 of their 97 opportunities.
• The Cubs are 44-53-0 against the spread in their 97 games that had a posted line this season.
• The Tigers have an 18-25 record in games they were listed as the moneyline underdog (winning 41.9% of those games).
• When it has played as a moneyline underdog with odds of +102 or longer, Detroit has a record of 14-17 (45.2%).
• The Tigers have had an over/under set by oddsmakers 99 times, and have combined with opponents to go over the total in 42 of those games (42-56-1).
• The Tigers have put together a 52-47-0 record ATS this season.

Cubs Player Leaders

• Pete Crow-Armstrong leads Chicago in OBP (.384), slugging percentage (.521) and total hits (107) this season. He has a .285 batting average.
• Among qualified batters in MLB, he ranks 23rd in batting average, 13th in on-base percentage, and 16th in slugging.
• Nico Hoerner is batting .247 with 23 doubles, a triple, four home runs and 36 walks, while slugging .340 with an on-base percentage of .314.
• His batting average ranks 90th among qualified players, his on-base percentage 99th, and his slugging percentage 139th.
• Hoerner takes a five-game streak with at least one hit into this contest. During his last five outings he is hitting .478 with a triple and five RBIs.
• Dansby Swanson is batting .215 with a .414 slugging percentage and 58 RBI this year.
• Swanson has logged a hit or more in two games in a row. In his last five games he is hitting .278 with a double, a triple and two walks.
• Alex Bregman has been key for Chicago with 94 hits, an OBP of .337 plus a slugging percentage of .362.
• Bregman enters this game on a three-game hitting streak. In his last five games he is batting .250 with a home run, two walks and three RBIs.

Tigers Player Leaders

• Kevin McGonigle has racked up a team-high OBP (.391) and slugging percentage (.425). He's batting .282.
• Including all qualifying hitters in MLB, his batting average puts him 30th, his on-base percentage is seventh, and he is 81st in slugging.
• McGonigle heads into this game on a four-game hitting streak. During his last five outings he is batting .263 with two doubles, a home run, three walks and an RBI.
• Dillon Dingler has 93 hits to pace his team. He has a batting average of .271 while slugging .536 with an on-base percentage of .336.
• His batting average ranks 47th among all qualified players, his on-base percentage ranks 68th, and he is 12th in slugging.
• Riley Greene is batting .285 with 20 doubles, a triple, 15 home runs and 53 walks.
• Spencer Torkelson is hitting .205 with 18 doubles, 18 home runs and 42 walks.

Cubs vs Tigers Head to Head

• 7/21/2026: 11-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 7/20/2026: 8-6 DET (Favorite: Cubs, Spread: -1.5, Total: 11.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/8/2025: 4-0 DET (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 6/7/2025: 6-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/6/2025: 3-1 DET (Favorite: Tigers, Spread: -1.5, Total: 7, Favorite Moneyline: -198, Underdog Moneyline: +166)
• 8/22/2024: 10-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 8/21/2024: 8-2 DET (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 8/20/2024: 3-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 8/22/2023: 8-6 DET (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 8/21/2023: 7-6 CHC (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -120, Underdog Moneyline: +102)

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