Cubs vs Tigers Prediction, Odds, Moneyline, Spread & Over/Under for July 21

Odds updated as of 7:12 p.m.

MLB action on Tuesday includes the Chicago Cubs taking on the Detroit Tigers.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Cubs vs Tigers Game Info

• Chicago Cubs (56-44) vs. Detroit Tigers (47-53)
• Date: Tuesday, July 21, 2026
• Time: 8:05 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: MARQ and DSN

Cubs vs Tigers Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-120) | DET: (+102)
• Spread: CHC: +1.5 (-196) | DET: -1.5 (+162)
• Total: 8 -- Over: (-104) | Under: (-118)

Cubs vs Tigers Probable Starting Pitchers

Probable Pitchers: David Peterson (Cubs) - 4-7, 6.45 ERA vs Framber Valdez (Tigers) - 5-6, 4.10 ERA

The Cubs will give the nod to David Peterson (4-7, 6.45 ERA), who is eyeing win No. 5 on the season, and the Tigers will counter with Framber Valdez (5-6, 4.10 ERA). Peterson's team is 3-8-0 against the spread this season in his starts. Peterson's team has a record of 2-4 this season when he starts and they are the favorite on the moneyline. The Tigers have an 8-10-0 record against the spread in Valdez's starts. The Tigers are 5-3 in Valdez's eight starts this season that they were the moneyline underdog.

Cubs vs Tigers Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (54.6%)

Cubs vs Tigers Moneyline

• The moneyline numbers for Cubs vs. Tigers reveal Chicago as the favorite (-120) and Detroit as the underdog (+102) on the road.

Cubs vs Tigers Spread

• The Tigers are 1.5-run favorites against the spread for this matchup with the Cubs. The Tigers are +162 to cover, while the Cubs are -196 to cover as a 1.5-run underdog on the runline.

Cubs vs Tigers Over/Under

• The Cubs-Tigers contest on July 21 has been given an over/under of 8 runs. The over is set at -104 and the under at -118.

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Cubs vs Tigers Betting Trends

• The Cubs have been chosen as favorites in 65 games this year and have walked away with the win 37 times (56.9%) in those games.
• This year Chicago has won 31 of 55 games when listed as at least -120 on the moneyline.
• The Cubs and their opponents have gone over in 52 of their 96 games with a total set by sportsbooks this season.
• The Cubs have an against the spread mark of 43-53-0 in 96 games with a line this season.
• The Tigers have won 42.9% of the games this season they were the underdog on the moneyline (18-24).
• When it has played as a moneyline underdog with odds of +102 or longer, Detroit has a record of 14-17 (45.2%).
• The Tigers have had an over/under set by oddsmakers 98 times, and have combined with opponents to go over the total in 41 of those games (41-56-1).
• The Tigers have collected a 52-46-0 record against the spread this season (covering 53.1% of the time).

Cubs Player Leaders

• Pete Crow-Armstrong leads Chicago with 105 hits and an OBP of .377, plus a team-best slugging percentage of .513. He's batting .281.
• Among qualified batters in MLB, his batting average ranks 32nd, his on-base percentage ranks 17th, and he is 17th in slugging.
• Nico Hoerner is hitting .247 with 23 doubles, a triple, four home runs and 36 walks. He's slugging .342 with an on-base percentage of .315.
• Among all qualifying hitters, he is 87th in batting average, 100th in on-base percentage and 137th in slugging percentage.
• Hoerner brings a four-game streak with at least one hit into this one. In his last five games he is batting .455 with a triple and five RBIs.
• Dansby Swanson has collected 69 base hits, an OBP of .291 and a slugging percentage of .412 this season.
• Michael Busch is batting .245 with a .370 OBP and 53 RBI for Chicago this season.
• Busch takes a six-game hitting streak into this matchup. During his last 10 outings he is batting .333 with three doubles, two home runs, five walks and six RBIs.

Tigers Player Leaders

• Kevin McGonigle has put up an on-base percentage of .391 and a slugging percentage of .426. Both lead the Tigers. He's batting .281.
• He is 32nd in batting average, seventh in on-base percentage and 76th in slugging percentage among all qualifying hitters in MLB.
• McGonigle hopes to build on a three-game hitting streak in this matchup. In his last five games he is hitting .211 with two doubles, a home run, four walks and an RBI.
• Dillon Dingler has collected 91 hits to lead his team. He has a batting average of .268 while slugging .524 with an on-base percentage of .332.
• He ranks 51st in batting average, 74th in on-base percentage and 14th in slugging percentage in the majors.
• Riley Greene has racked up a team-high .475 slugging percentage.
• Spencer Torkelson is hitting .206 with 18 doubles, 18 home runs and 41 walks.

Cubs vs Tigers Head to Head

• 7/20/2026: 8-6 DET (Favorite: Cubs, Spread: -1.5, Total: 11.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/8/2025: 4-0 DET (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 6/7/2025: 6-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/6/2025: 3-1 DET (Favorite: Tigers, Spread: -1.5, Total: 7, Favorite Moneyline: -198, Underdog Moneyline: +166)
• 8/22/2024: 10-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 8/21/2024: 8-2 DET (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 8/20/2024: 3-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 8/22/2023: 8-6 DET (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 8/21/2023: 7-6 CHC (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -120, Underdog Moneyline: +102)

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