Cubs vs Reds Prediction, Odds, Moneyline, Spread & Over/Under for May 7

Odds updated as of 2:11 p.m.

The Chicago Cubs versus the Cincinnati Reds is on the MLB schedule for Thursday.

We've got you covered, in terms of the most important info regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Cubs vs Reds Game Info

• Chicago Cubs (25-12) vs. Cincinnati Reds (20-17)
• Date: Thursday, May 7, 2026
• Time: 2:20 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: MARQ and Reds.TV

Cubs vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-198) | CIN: (+166)
• Spread: CHC: -1.5 (+102) | CIN: +1.5 (-122)
• Total: 9 -- Over: (-105) | Under: (-115)

Cubs vs Reds Probable Starting Pitchers

Probable Pitchers: Shota Imanaga (Cubs) - 3-2, 2.40 ERA vs Rhett Lowder (Reds) - 3-2, 5.09 ERA

The Cubs will give the ball to Shota Imanaga (3-2, 2.40 ERA), who is eyeing win No. 4 on the season, and the Reds will counter with Rhett Lowder (3-2, 5.09 ERA). Imanaga and his team are 3-4-0 ATS this season when he starts. Imanaga's team is 2-3 this season when he starts and they are the moneyline favorite. The Reds are 4-3-0 against the spread when Lowder starts. The Reds have a 4-2 record in Lowder's six starts this season when they were the moneyline underdog.

Cubs vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (64.4%)

Cubs vs Reds Moneyline

• Cincinnati is the underdog, +166 on the moneyline, while Chicago is a -198 favorite at home.

Cubs vs Reds Spread

• The Reds are +1.5 on the run line against the Cubs. The Reds are -122 to cover, and the Cubs are +102.

Cubs vs Reds Over/Under

• An over/under of 9 has been set for Cubs-Reds on May 7, with the over being -105 and the under -115.

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Cubs vs Reds Betting Trends

• The Cubs have been victorious in 17, or 70.8%, of the 24 contests they have been chosen as favorites in this season.
• This season Chicago has been victorious two times in four chances when named as a favorite of at least -198 on the moneyline.
• The Cubs and their opponents have gone over the total this season in 23 of their 36 opportunities.
• The Cubs are 17-19-0 against the spread in their 36 games that had a posted line this season.
• The Reds have won 58.3% of the games this season they were the underdog on the moneyline (14-10).
• Cincinnati has not played a game this season with moneyline odds of +166 or longer.
• The Reds have played in 35 games with an over/under set, and have combined with their opponents to go over the total 21 times (21-13-1).
• The Reds have a 22-13-0 record against the spread this season.

Cubs Player Leaders

• Nico Hoerner leads Chicago in slugging percentage (.441) thanks to 14 extra-base hits. He has a .290 batting average and an on-base percentage of .365.
• Among all qualifying hitters in MLB, he is 35th in batting average, 47th in on-base percentage, and 59th in slugging.
• Ian Happ has 33 hits and an OBP of .379, both of which lead the Cubs this season. He's batting .248 and slugging .511.
• He is 86th in batting average, 30th in on-base percentage and 28th in slugging in the major leagues.
• Dansby Swanson is batting .207 with a .388 slugging percentage and 24 RBI this year.
• Swanson has picked up a hit in two straight games. During his last five outings he is hitting .158 with a walk.
• Alex Bregman is batting .245 with a .341 OBP and 13 RBI for Chicago this season.
• Bregman takes a three-game hitting streak into this game. During his last five outings he is batting .158 with a double, four walks and an RBI.

Reds Player Leaders

• Sal Stewart is hitting .245 with six doubles, nine home runs and 19 walks. He's slugging .482 with an on-base percentage of .331.
• Including all qualified players in the big leagues, he ranks 94th in batting average, 90th in on-base percentage and 37th in slugging percentage.
• Elly De La Cruz has 39 hits with a .341 on-base percentage while slugging .514. Those stats all lead his team. He also has a batting average of .267.
• His batting average ranks 56th among all qualified players, his on-base percentage ranks 74th, and he is 25th in slugging.
• Nathaniel Lowe has five doubles, six home runs and nine walks while batting .274.
• Spencer Steer has six doubles, six home runs and 10 walks while batting .252.

Cubs vs Reds Head to Head

• 5/6/2026: 7-6 CHC (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 5/5/2026: 3-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 9/20/2025: 6-3 CIN (Favorite: Reds, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 9/19/2025: 7-4 CIN (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 9/18/2025: 1-0 CIN (Favorite: Reds, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 8/6/2025: 6-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 8/5/2025: 5-1 CIN (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 8/4/2025: 3-2 CIN (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 6/1/2025: 7-3 CHC (Favorite: Cubs, Spread: -1.5, Total: 7, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 5/31/2025: 2-0 CHC (Favorite: Cubs, Spread: -1.5, Total: 7, Favorite Moneyline: -178, Underdog Moneyline: +150)

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