Cubs vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for June 29

Odds updated as of 2:12 a.m.

The Monday slate in MLB includes a matchup between the Chicago Cubs and the San Diego Padres.

We've got you covered, in terms of the most important info regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Cubs vs Padres Game Info

• Chicago Cubs (46-38) vs. San Diego Padres (43-39)
• Date: Monday, June 29, 2026
• Time: 8:05 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: MARQ and Padres.TV

Cubs vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-154) | SD: (+130)
• Spread: CHC: -1.5 (+122) | SD: +1.5 (-146)
• Total: 11.5 -- Over: (-114) | Under: (-106)

Cubs vs Padres Probable Starting Pitchers

Probable Pitchers: Shota Imanaga (Cubs) - 5-6, 4.40 ERA vs TBA (Padres)

The Cubs will look to Shota Imanaga (5-6), while the Padres' starter has not yet been announced. Imanaga and his team are 5-11-0 ATS this season when he starts. Imanaga's team has won 42.9% of his starts when they are favored on the moneyline (6-8).

Cubs vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (61.7%)

Cubs vs Padres Moneyline

• Chicago is the favorite, -154 on the moneyline, while San Diego is a +130 underdog on the road.

Cubs vs Padres Spread

• The Padres are at +1.5 on the runline against the Cubs. The Padres are -146 to cover the spread, and the Cubs are +122.

Cubs vs Padres Over/Under

• The over/under for Cubs-Padres on June 29 is 11.5. The over is -114, and the under is -106.

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Cubs vs Padres Betting Trends

• The Cubs have won in 30, or 55.6%, of the 54 contests they have been named as odds-on favorites in this year.
• Chicago has a record of 13-7 when favored by -154 or more this year.
• The Cubs and their opponents have gone over the total this season in 44 of their 82 opportunities.
• In 82 games with a line this season, the Cubs have a mark of 34-48-0 against the spread.
• The Padres have won 22 of the 45 games they were the moneyline underdog this season (48.9%).
• When playing as a moneyline underdog with odds of +130 or longer, San Diego has a 2-8 record (winning only 20% of its games).
• The Padres have had an over/under set by bookmakers 82 times, and have combined with opponents to go over the total in 36 of those games (36-45-1).
• The Padres have put together a 45-37-0 record ATS this season (covering 54.9% of the time).

Cubs Player Leaders

• Pete Crow-Armstrong has 88 hits to go with a slugging percentage of .505, both of which are best among Chicago hitters this season. He has a .278 batting average and an on-base percentage of .364.
• Among qualifying hitters in MLB, his batting average ranks 36th, his on-base percentage ranks 30th, and he is 23rd in slugging.
• Nico Hoerner has 21 doubles, four home runs and 34 walks. He's batting .242 and slugging .342 with an on-base percentage of .317.
• He is 100th in batting average, 103rd in on-base percentage and 137th in slugging in the majors.
• Hoerner brings a two-game streak with at least one hit into this contest. In his last five games he is hitting .350 with three doubles, a walk and an RBI.
• Ian Happ is batting .224 with a .458 slugging percentage and 41 RBI this year.
• Michael Busch leads Chicago with an OBP of .370 this season while batting .236 with 58 walks and 33 runs scored.

Padres Player Leaders

• Manny Machado is hitting .188 with 15 doubles, 15 home runs and 36 walks. He's slugging .392 with an on-base percentage of .272.
• He ranks 155th in batting average, 149th in on-base percentage and 105th in slugging percentage among all qualified hitters in MLB.
• Fernando Tatis Jr.'s .347 on-base percentage and .366 slugging percentage both pace his team. He has a batting average of .283.
• He ranks 27th in batting average, 52nd in on-base percentage and 126th in slugging percentage in the big leagues.
• Gavin Sheets paces the Padres with 55 hits.
• Xander Bogaerts has four doubles, eight home runs and 34 walks while batting .229.

Cubs vs Padres Head to Head

• 4/29/2026: 5-4 CHC (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/28/2026: 8-3 CHC (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: +100)
• 4/27/2026: 9-7 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 10/2/2025: 3-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 10/1/2025: 3-0 SD (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/30/2025: 3-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 4/16/2025: 4-2 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 4/15/2025: 2-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 4/14/2025: 10-4 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 4/6/2025: 8-7 SD (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)

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