Cubs vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for June 24

Odds updated as of 7:11 p.m.

In MLB action on Tuesday, the Chicago Cubs take on the St. Louis Cardinals.

All the information you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Cubs vs Cardinals Game Info

• Chicago Cubs (46-32) vs. St. Louis Cardinals (43-36)
• Date: Tuesday, June 24, 2025
• Time: 7:45 p.m. ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: FDSMW and MARQ

Cubs vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-116) | STL: (-102)
• Spread: CHC: -1.5 (+150) | STL: +1.5 (-182)
• Total: 8.5 -- Over: (-122) | Under: (-100)

Cubs vs Cardinals Probable Starting Pitchers

Probable Pitchers: Jameson Taillon (Cubs) - 7-4, 3.84 ERA vs Michael McGreevy (Cardinals) - 0-0, 0.00 ERA

The Cubs will give the nod to Jameson Taillon (7-4, 3.84 ERA), who is eyeing win No. 8 on the season, and the Cardinals will counter with Michael McGreevy. Taillon and his team are 7-7-0 ATS this season when he starts. When Taillon starts a game and his team is the favorite on the moneyline, they have a record of 7-3. McGreevy's team was never a moneyline underdog a season ago in games he pitched.

Cubs vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (54.9%)

Cubs vs Cardinals Moneyline

• Looking at the moneyline for Cardinals-Cubs, St. Louis is the underdog at -102, and Chicago is -116 playing on the road.

Cubs vs Cardinals Spread

• The Cardinals are at +1.5 on the runline against the Cubs. The Cardinals are -182 to cover the spread, and the Cubs are +150.

Cubs vs Cardinals Over/Under

• An over/under of 8.5 has been set for Cubs-Cardinals on June 24, with the over being -122 and the under -100.

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Cubs vs Cardinals Betting Trends

• The Cubs have come away with 35 wins in the 50 contests they have been listed as the favorites in this season.
• This season Chicago has come away with a win 34 times in 48 chances when named as a favorite of at least -116 on the moneyline.
• Contests with the Cubs have gone over the total set by oddsmakers in 41 of 76 chances this season.
• The Cubs are 38-38-0 against the spread in their 76 games with a line set by sportsbooks this season.
• The Cardinals have been the moneyline underdog 43 total times this season. They've finished 23-20 in those games.
• St. Louis has a record of 16-19 in games it has played as a moneyline underdog with odds of -102 or longer (45.7%).
• The Cardinals have played in 79 games with a set over/under, and have combined with opponents to go over the total 42 times (42-34-3).
• The Cardinals have covered 54.4% of their games this season, going 43-36-0 ATS.

Cubs Player Leaders

• Kyle Tucker leads Chicago with an OBP of .391 this season while batting .281 with 51 walks and 55 runs scored. He has a slugging percentage of .521.
• Among all qualifying hitters in MLB, he is 38th in batting average, seventh in on-base percentage, and 17th in slugging.
• Pete Crow-Armstrong leads Chicago in slugging percentage (.567) and total hits (82) this season. He's batting .273 with an on-base percentage of .310.
• He is 52nd in batting average, 117th in on-base percentage and seventh in slugging in MLB.
• Crow-Armstrong enters this matchup looking to extend his three-game hit streak. In his last five games he is hitting .333 with three doubles, two home runs and three RBIs.
• Seiya Suzuki has collected 76 base hits, an OBP of .311 and a slugging percentage of .535 this season.
• Suzuki has recorded a hit in two games in a row. In his last five games he is batting .190 with a double, two home runs, a walk and three RBIs.
• Nico Hoerner leads Chicago with a slugging percentage of .354, fueled by 18 extra-base hits.
• Hoerner has safely hit in two straight games. In his last five games he is batting .278 with two RBIs.

Cardinals Player Leaders

• Nolan Arenado is hitting .251 with 11 doubles, a triple, 10 home runs and 23 walks. He's slugging .405 with an on-base percentage of .313.
• Including all the qualifying hitters in MLB, he is 99th in batting average, 114th in on-base percentage and 107th in slugging percentage.
• Arenado hopes to build on a four-game hitting streak in this matchup. During his last five outings he is batting .333 with two home runs, a walk and three RBIs.
• Brendan Donovan leads his team with a .375 OBP, and has a club-leading .437 slugging percentage. He has a batting average of .307.
• He is currently 10th in batting average, 22nd in on-base percentage and 72nd in slugging percentage among all qualifying hitters.
• Lars Nootbaar is batting .229 with 13 doubles, 10 home runs and 43 walks.
• Willson Contreras is batting .248 with 18 doubles, 10 home runs and 25 walks.

Cubs vs Cardinals Head to Head

• 6/23/2025: 8-2 STL (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/4/2024: 6-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 8/3/2024: 5-4 STL (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/2/2024: 6-3 CHC (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/1/2024: 5-4 CHC (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 7/14/2024: 8-3 CHC (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/13/2024: 5-4 STL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 7/13/2024: 11-3 STL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 7/12/2024: 5-1 CHC (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -196, Underdog Moneyline: +164)
• 6/16/2024: 2-1 STL (Favorite: Cubs, Spread: -1.5, Total: 10.5, Favorite Moneyline: -130, Underdog Moneyline: +110)

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