Clemson vs SMU Basketball Prediction, Odds, Picks, Best Bets for February 22

The Clemson Tigers (21-5, 13-2 ACC) will attempt to continue a five-game road winning streak when they take on the SMU Mustangs (20-6, 11-4 ACC) on February 22, 2025 at Moody Coliseum.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Clemson vs. SMU Game Info and Odds

• Game day: Saturday, February 22, 2025
• Game time: 4:00 PM ET
• TV channel: ACC Network
• Location: Dallas, Texas
• Arena: Moody Coliseum

Clemson vs. SMU Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: SMU win (54.4%)

Check out the betting insights and trends below before making a wager on Saturday's Clemson-SMU spread (Clemson -1.5) or over/under (144.5 points).

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Clemson vs. SMU: ATS Betting Stats and Trends

• Clemson has won 16 games against the spread this season, while failing to cover 10 times.
• SMU has won 13 games against the spread this year, while failing to cover 13 times.
• Clemson covers the spread when it is a 1.5-point favorite or more 60% of the time. That's more often than SMU covers as an underdog of 1.5 or more (never covered this season).
• At home, the Tigers have a worse record against the spread (8-7-0) compared to their ATS record on the road (6-3-0).
• The Mustangs' winning percentage against the spread at home is .467 (7-8-0). On the road, it is .500 (4-4-0).
• Clemson has beaten the spread 11 times in 15 conference games.
• SMU is 8-7-0 against the spread in ACC games this season.

Clemson vs. SMU: Moneyline Betting Stats

• Clemson has come away with 16 wins in the 19 contests it has been listed as the moneyline favorite in this season.
• This year, the Tigers have won 16 of 18 games when listed as at least -128 or better on the moneyline.
• SMU has a 1-3 record in games it was the underdog on the moneyline (winning 25% of those games).
• The Mustangs have played as a moneyline underdog of +106 or longer in just two games this season, which they lost both.
• The moneyline set for this matchup implies Clemson has a 56.1% chance of walking away with the win.

Clemson vs. SMU Head-to-Head Comparison

• Clemson outscores opponents by 11 points per game (scoring 77.4 per game to rank 90th in college basketball while allowing 66.4 per outing to rank 38th in college basketball) and has a +287 scoring differential overall.
• Chase Hunter ranks 115th in college basketball with a team-leading 17 points per game.
• SMU's +293 scoring differential (outscoring opponents by 11.3 points per game) is a result of putting up 82.7 points per game (20th in college basketball) while giving up 71.4 per contest (169th in college basketball).
• Kevin Miller is 461st in the nation with a team-high 13.4 points per game.
• The Tigers win the rebound battle by an average of 3.3 boards. They are pulling down 32.8 rebounds per game (138th in college basketball) compared to their opponents' 29.5 per contest.
• Ian Schieffelin averages 9.6 rebounds per game (ranking 17th in college basketball) to lead the Tigers.
• The Mustangs record 35.6 rebounds per game (30th in college basketball) while conceding 29.3 per contest to opponents. They outrebound opponents by 6.3 boards per game.
• Matt Cross averages 8.2 rebounds per game (56th in college basketball) to lead the Mustangs.
• Clemson ranks 44th in college basketball by averaging 102.1 points per 100 possessions on offense, and defensively is 52nd in college basketball, allowing 87.5 points per 100 possessions.
• The Mustangs rank 38th in college basketball with 102.9 points scored per 100 possessions, and 81st defensively with 88.9 points conceded per 100 possessions.

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