Cardinals vs Reds Prediction, Odds, Moneyline, Spread & Over/Under for July 24

Odds updated as of 8:11 p.m.

The Friday schedule in MLB includes a matchup between the St. Louis Cardinals and the Cincinnati Reds.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital information regarding this matchup.

Cardinals vs Reds Game Info

• St. Louis Cardinals (52-50) vs. Cincinnati Reds (47-54)
• Date: Friday, July 24, 2026
• Time: 8:15 p.m. ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: Cardinals.TV and Reds.TV

Cardinals vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: STL: (-118) | CIN: (+100)
• Spread: STL: +1.5 (-205) | CIN: -1.5 (+168)
• Total: 8.5 -- Over: (-110) | Under: (-110)

Cardinals vs Reds Probable Starting Pitchers

Probable Pitchers: Dustin May (Cardinals) - 5-7, 4.78 ERA vs Rhett Lowder (Reds) - 3-7, 5.75 ERA

This contest's pitching matchup is set, as the Cardinals will send Dustin May (5-7) to the mound, while Rhett Lowder (3-7) will get the nod for the Reds. May's team is 11-8-0 against the spread this season in his starts. When May starts a game and his team is the favorite on the moneyline, they have a record of 4-1. The Reds are 6-8-0 against the spread when Lowder starts. The Reds are 5-7 in Lowder's 12 starts this season that they were the moneyline underdog.

Cardinals vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (60.8%)

Cardinals vs Reds Moneyline

• The moneyline numbers for Cardinals vs. Reds reveal St. Louis as the favorite (-118) and Cincinnati as the underdog (+100) on the road.

Cardinals vs Reds Spread

• The Reds are 1.5-run favorites against the spread for this matchup with the Cardinals. The Reds are +168 to cover, while the Cardinals are -205 to cover as a 1.5-run underdog on the runline.

Cardinals vs Reds Over/Under

• A total of 8.5 runs has been set for the Cardinals-Reds game on July 24, with the over available at -110 and the under at -110.

Bet on St. Louis Cardinals vs. Cincinnati Reds on FanDuel today!

Cardinals vs Reds Betting Trends

• The Cardinals have been chosen as favorites in 28 games this year and have walked away with the win 16 times (57.1%) in those games.
• This season St. Louis has come away with a win 11 times in 17 chances when named as a favorite of at least -118 on the moneyline.
• The Cardinals and their opponents have gone over in 41 of their 100 games with a total set by sportsbooks this season.
• The Cardinals are 56-44-0 against the spread in their 100 games with a line set by sportsbooks this season.
• The Reds have been the moneyline underdog 67 total times this season. They've finished 31-36 in those games.
• Cincinnati has a 21-35 record (winning just 37.5% of its games) when playing as a moneyline underdog of +100 or longer.
• The Reds have had an over/under set by oddsmakers 99 times, and have combined with opponents to go over the total in 55 of those games (55-43-1).
• The Reds have a 54-45-0 record against the spread this season (covering 54.5% of the time).

Cardinals Player Leaders

• Jordan Walker leads St. Louis with 112 hits and a team-best slugging percentage of .519. He's batting .291 with an on-base percentage of .352.
• Among qualified hitters in MLB, his batting average ranks 15th, his on-base percentage ranks 46th, and he is 15th in slugging.
• Alec Burleson is hitting .284 with 25 doubles, a triple, 15 home runs and 34 walks, while slugging .469 with an on-base percentage of .345.
• He is 24th in batting average, 59th in on-base percentage and 39th in slugging in the majors.
• JJ Wetherholt has 99 hits this season and has a slash line of .259/.352/.403.
• Wetherholt has recorded a hit in two straight games. During his last five outings he is hitting .182 with a home run, a walk and three RBIs.
• Ivan Herrera leads St. Louis with an OBP of .366 this season while batting .241 with 51 walks and 62 runs scored.

Reds Player Leaders

• Sal Stewart has a .472 slugging percentage, which paces the Reds. He's batting .249 with an on-base percentage of .327.
• Including all the qualifying hitters in MLB, he ranks 86th in batting average, 82nd in on-base percentage and 37th in slugging percentage.
• Elly De La Cruz has 90 hits with a .351 OBP to lead his team in both. He has a batting average of .276 while slugging .503.
• He is currently 40th in batting average, 48th in on-base percentage and 21st in slugging percentage among all qualifying hitters.
• JJ Bleday has 11 doubles, a triple, 17 home runs and 41 walks while hitting .237.
• Spencer Steer has 14 doubles, 16 home runs and 34 walks while batting .242.

Cardinals vs Reds Head to Head

• 6/7/2026: 5-3 STL (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 6/6/2026: 6-5 STL (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 6/5/2026: 10-3 STL (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/23/2026: 7-6 CIN (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 5/23/2026: 8-1 STL (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 9/17/2025: 6-2 CIN (Favorite: Reds, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 9/16/2025: 3-0 STL (Favorite: Reds, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 9/15/2025: 11-6 CIN (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/31/2025: 7-4 CIN (Favorite: Reds, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/30/2025: 4-2 STL (Favorite: Reds, Spread: -1.5, Total: 8, Favorite Moneyline: -142, Underdog Moneyline: +120)

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