Cardinals vs Reds Prediction, Odds, Moneyline, Spread & Over/Under for June 20

Odds updated as of 7:15 a.m.

Friday's slate in the MLB includes a matchup between the St. Louis Cardinals and the Cincinnati Reds.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's what you need to know.

Cardinals vs Reds Game Info

• St. Louis Cardinals (40-35) vs. Cincinnati Reds (39-36)
• Date: Friday, June 20, 2025
• Time: 7:15 p.m. ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: FDSMW and FDSOH

Cardinals vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: STL: (-136) | CIN: (+116)
• Spread: STL: -1.5 (+150) | CIN: +1.5 (-182)
• Total: 9 -- Over: (-102) | Under: (-120)

Cardinals vs Reds Probable Starting Pitchers

Probable Pitchers: Andre Pallante (Cardinals) - 4-3, 4.83 ERA vs Brady Singer (Reds) - 7-4, 4.34 ERA

The Cardinals will give the ball to Andre Pallante (4-3, 4.83 ERA), who is eyeing win No. 5 on the season, and the Reds will counter with Brady Singer (7-4, 4.34 ERA). When Pallante starts, his team is 9-5-0 against the spread this season. Pallante's team is 2-3 this season when he starts and they are the moneyline favorite. When Singer starts, the Reds are 10-4-0 against the spread. The Reds have a 7-1 record in Singer's eight starts this season when they were the moneyline underdog.

Cardinals vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (55.7%)

Cardinals vs Reds Moneyline

• Cincinnati is the underdog, +116 on the moneyline, while St. Louis is a -136 favorite at home.

Cardinals vs Reds Spread

• The Cardinals are hosting the Reds and are favored by 1.5 runs on the spread. The Cardinals are +150 to cover the runline, with the Reds being -182.

Cardinals vs Reds Over/Under

• A combined run total of 9 has been set for Cardinals-Reds on June 20, with the over at -102 and the under at -120.

Bet on St. Louis Cardinals vs. Cincinnati Reds on FanDuel today!

Cardinals vs Reds Betting Trends

• The Cardinals have been favorites in 33 games this season and have come away with the win 17 times (51.5%) in those contests.
• St. Louis has a record of 6-4 in contests when sportsbooks favor them by -136 or more on the moneyline.
• The Cardinals and their opponents have hit the over in 40 of their 75 games with a total set by oddsmakers this season.
• In 75 games with a line this season, the Cardinals have a mark of 41-34-0 against the spread.
• The Reds have won 21 of the 40 games they were the moneyline underdog this season (52.5%).
• When it has played as a moneyline underdog with odds of +116 or longer, Cincinnati has a 7-9 record (winning 43.8% of its games).
• The Reds have played in 71 games with a set over/under, and have combined with opponents to go over the total 33 times (33-36-2).
• The Reds have gone 37-34-0 ATS this season.

Cardinals Player Leaders

• Nolan Arenado is batting .247 with 11 doubles, a triple, nine home runs and 23 walks. He has an on-base percentage of .310 while slugging .397.
• He is 96th in batting average, 111th in on-base percentage, and 110th in slugging among qualified batters in baseball.
• Brendan Donovan leads St. Louis in OBP (.381), slugging percentage (.443) and total hits (83) this season. He's batting .317.
• He ranks eighth in batting average, 14th in on-base percentage and 63rd in slugging in the majors.
• Willson Contreras has 66 hits this season and has a slash line of .249/.339/.423.
• Contreras enters this matchup with two games in a row with at least one hit. In his last five games he is hitting .167 with a double, two home runs, three walks and seven RBIs.
• Lars Nootbaar is batting .225 with a .333 OBP and 30 RBI for St. Louis this season.
• Nootbaar brings a two-game hitting streak into this matchup. During his last five outings he is hitting .111 with a home run, four walks and two RBIs.

Reds Player Leaders

• Elly De La Cruz has 75 hits, a team-best for the Reds. He's batting .263 and slugging .481 with an on-base percentage of .345.
• Including all qualified hitters, he ranks 64th in batting average, while his on-base percentage is 57th and he is 29th in slugging.
• TJ Friedl leads his team with a .384 OBP, and has a club-high .445 slugging percentage. He has a batting average of .294.
• Including all qualified hitters, his batting average puts him 18th, his on-base percentage is 13th, and he is 62nd in slugging.
• Gavin Lux is hitting .275 with 14 doubles, a triple, three home runs and 31 walks.
• Matt McLain is hitting .197 with five doubles, eight home runs and 27 walks.

Cardinals vs Reds Head to Head

• 5/1/2025: 9-1 CIN (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 4/30/2025: 9-1 STL (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 4/30/2025: 6-0 STL (Favorite: Reds, Spread: -1.5, Total: 9, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 4/28/2025: 3-1 CIN (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 9/12/2024: 6-1 STL (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 9/11/2024: 2-1 STL (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 9/10/2024: 3-0 CIN (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 8/14/2024: 9-2 CIN (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/13/2024: 4-1 CIN (Favorite: Reds, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 8/12/2024: 6-1 CIN (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -138, Underdog Moneyline: +118)

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