Cardinals vs Athletics Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 2

Odds updated as of 7:17 p.m.

The Athletics will take on the St. Louis Cardinals in MLB action on Tuesday.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Athletics vs Cardinals Game Info

• Athletics (64-75) vs. St. Louis Cardinals (68-71)
• Date: Tuesday, September 2, 2025
• Time: 7:45 p.m. ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: FDSMW and NBCS-CA

Athletics vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: OAK: (-110) | STL: (-106)
• Spread: OAK: -1.5 (+142) | STL: +1.5 (-172)
• Total: 8.5 -- Over: (-110) | Under: (-110)

Athletics vs Cardinals Probable Starting Pitchers

Probable Pitchers: Luis Severino (Athletics) - 6-11, 4.82 ERA vs Miles Mikolas (Cardinals) - 6-10, 5.04 ERA

The Athletics will give the nod to Luis Severino (6-11, 4.82 ERA), who is eyeing win No. 7 on the season, and the Cardinals will counter with Miles Mikolas (6-10, 5.04 ERA). When Severino starts, his team is 11-12-0 against the spread this season. Severino's team is 1-1 this season when he starts and they're favored on the moneyline. The Cardinals have gone 11-15-0 ATS in Mikolas' 26 starts that had a set spread. The Cardinals are 7-11 in Mikolas' 18 starts this season that they were the moneyline underdog.

Athletics vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (50.7%)

Athletics vs Cardinals Moneyline

• The Athletics vs Cardinals moneyline has the Athletics as a -110 favorite, while the Cardinals are a -106 underdog at home.

Athletics vs Cardinals Spread

• The Athletics are 1.5-run favorites on the runline against the Cardinals. The Athletics are +142 to cover, while the Cardinals are -172 to cover.

Athletics vs Cardinals Over/Under

• Athletics versus Cardinals on Sept. 2 has an over/under of 8.5 runs, with the odds on the over -110 and the under set at -110.

Bet on Athletics vs. St. Louis Cardinals on FanDuel today!

Athletics vs Cardinals Betting Trends

• The Athletics have been victorious in 15, or 48.4%, of the 31 contests they have been chosen as favorites in this season.
• This year, the Athletics have won 15 of 31 games when listed as at least -110 or better on the moneyline.
• The Athletics and their opponents have hit the over in 70 of their 138 games with a total this season.
• The Athletics are 73-65-0 against the spread in their 138 games with a line set by sportsbooks this season.
• The Cardinals have gone 35-37 in games they were the underdog on the moneyline (winning 48.6% of those games).
• When playing as a moneyline underdog with odds of -106 or longer, the Cardinals have gone 35-36 (49.3%).
• The Cardinals have combined with their opponents to go over the total 70 times this season for a 70-58-5 record against the over/under.
• The Cardinals have put together a 67-66-0 record against the spread this season (covering 50.4% of the time).

Athletics Player Leaders

• Brent Rooker leads Sacramento with a slugging percentage of .495, fueled by 65 extra-base hits. He has a .270 batting average and an on-base percentage of .342.
• He is 45th in batting average, 52nd in on-base percentage, and 24th in slugging among qualified hitters in the majors.
• Tyler Soderstrom is hitting .271 with 28 doubles, a triple, 23 home runs and 51 walks, while slugging .470 with an on-base percentage of .344.
• He is 43rd in batting average, 49th in on-base percentage and 43rd in slugging among qualified hitters.
• Soderstrom brings a two-game streak with at least one hit into this contest. During his last five outings he is batting .200 with two doubles, a walk and five RBIs.
• Shea Langeliers leads Sacramento in total hits (105) this season, and 53 of those have gone for extra bases.
• Nick Kurtz is batting .308 with a .402 OBP and 70 RBI for Sacramento this season.

Cardinals Player Leaders

• Willson Contreras is batting .251 with 30 doubles, 20 home runs and 41 walks. He's slugging .443 with an on-base percentage of .335.
• Including all the qualifying hitters in MLB, he ranks 93rd in batting average, 67th in on-base percentage and 71st in slugging percentage.
• Masyn Winn is hitting .256 with 27 doubles, nine home runs and 32 walks. He's slugging .370 with an on-base percentage of .311.
• Including all qualifying hitters, he ranks 87th in batting average, 113th in on-base percentage and 137th in slugging percentage.
• Lars Nootbaar is hitting .244 with 22 doubles, a triple, 13 home runs and 54 walks.
• Ivan Herrera has 11 doubles, 12 home runs and 33 walks while hitting .286.

Athletics vs Cardinals Head to Head

• 9/1/2025: 11-3 OAK (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 4/17/2024: 6-3 OAK (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 4/16/2024: 3-2 STL (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 4/15/2024: 3-1 STL (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 8/16/2023: 8-0 OAK (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -178, Underdog Moneyline: +150)
• 8/15/2023: 6-2 STL (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 8/14/2023: 7-5 STL (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -240, Underdog Moneyline: +198)

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