Brewers vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for May 6

Odds updated as of 7:11 p.m.

The Milwaukee Brewers are among the MLB teams busy on Tuesday, versus the Houston Astros.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's everything you need to know.

Brewers vs Astros Game Info

• Milwaukee Brewers (18-18) vs. Houston Astros (17-17)
• Date: Tuesday, May 6, 2025
• Time: 7:40 p.m. ET
• Venue: American Family Field -- Milwaukee, Wisconsin
• Coverage: FDSWI and SCHN

Brewers vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIL: (-122) | HOU: (+104)
• Spread: MIL: -1.5 (+160) | HOU: +1.5 (-194)
• Total: 8 -- Over: (-110) | Under: (-110)

Brewers vs Astros Probable Starting Pitchers

Probable Pitchers: Chad Patrick (Brewers) - 1-3, 2.87 ERA vs Hayden Wesneski (Astros) - 1-2, 3.86 ERA

The Brewers will call on Chad Patrick (1-3) versus the Astros and Hayden Wesneski (1-2). Patrick and his team have a record of 4-2-0 against the spread when he starts. Patrick's team has been victorious in 50% of the games he's started as the moneyline favorite with a record of 2-2. The Astros have a 3-2-0 ATS record in Wesneski's five starts that had a set spread. The Astros have a 1-2 record in Wesneski's three starts this season when they were the underdog on the moneyline.

Brewers vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Brewers win (51.7%)

Brewers vs Astros Moneyline

• Milwaukee is a -122 favorite on the moneyline, while Houston is a +104 underdog on the road.

Brewers vs Astros Spread

• The Astros are at the Brewers, and are +1.5 on the runline. The Astros are +160 to cover the spread, and the Brewers are -194.

Brewers vs Astros Over/Under

• The over/under for the Brewers versus Astros contest on May 6 has been set at 8, with -110 odds on the over and -110 odds on the under.

Bet on Milwaukee Brewers vs. Houston Astros on FanDuel today!

Brewers vs Astros Betting Trends

• The Brewers have won in 13, or 72.2%, of the 18 contests they have been named as odds-on favorites in this year.
• Milwaukee has a record of 10-4 in contests when bookmakers favor them by -122 or more on the moneyline.
• The Brewers and their opponents have gone over in 15 of their 36 games with a total set by sportsbooks this season.
• The Brewers are 21-15-0 against the spread in their 36 games that had a posted line this season.
• The Astros are 5-4 in games they were listed as the moneyline underdog (winning 55.6% of those games).
• Houston is 1-3 (winning just 25% of its games) when it has played as a moneyline underdog of +104 or longer.
• The Astros have played in 34 games with a set over/under, and have combined with their opponents to go over the total 15 times (15-17-2).
• The Astros have covered 52.9% of their games this season, going 18-16-0 against the spread.

Brewers Player Leaders

• Jackson Chourio has 39 hits, which is tops among Milwaukee hitters this season, while batting .255 with 19 extra-base hits. He has an on-base percentage of .268 and a slugging percentage of .464.
• Among qualifying hitters in baseball, he is 72nd in batting average, 142nd in on-base percentage, and 47th in slugging.
• Chourio will look for his fourth straight game with a hit in this contest. During his last five outings he is batting .150 with a double.
• Brice Turang leads Milwaukee in slugging percentage (.400) thanks to five extra-base hits. He's batting .315 with an on-base percentage of .372.
• Among all qualified, he is 11th in batting average, 32nd in on-base percentage and 87th in slugging percentage.
• William Contreras has collected 30 base hits, an OBP of .361 and a slugging percentage of .339 this season.
• Contreras has picked up a hit in two straight games. In his last five games he is batting .176 with two walks and an RBI.
• Christian Yelich has been key for Milwaukee with 26 hits, an OBP of .317 plus a slugging percentage of .379.
• Yelich has safely hit in two straight games. In his last five games he is batting .100 with a home run, a walk and two RBIs.

Astros Player Leaders

• Jeremy Pena has accumulated a slugging percentage of .414 and has 36 hits, both team-high numbers for the Astros. He's batting .281 and with an on-base percentage of .345.
• Including all the qualifying hitters in the majors, he ranks 39th in batting average, 60th in on-base percentage and 75th in slugging percentage.
• Pena takes a nine-game hitting streak into this game. During his last 10 outings he is hitting .341 with two doubles, a home run, two walks and four RBIs.
• Isaac Paredes' .357 on-base percentage leads his team. He has a batting average of .258 while slugging .395.
• He is 68th in batting average, 47th in on-base percentage and 95th in slugging percentage in the big leagues.
• Jose Altuve has four doubles, four home runs and nine walks while hitting .259.
• Jake Meyers is batting .301 with five doubles, a triple, two home runs and eight walks.

Brewers vs Astros Head to Head

• 5/5/2025: 5-1 MIL (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 5/19/2024: 9-4 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 5/18/2024: 4-2 MIL (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 5/17/2024: 5-4 HOU (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/24/2023: 4-0 MIL (Favorite: Brewers, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/23/2023: 6-0 MIL (Favorite: Astros, Spread: -1.5, Total: 9.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/22/2023: 12-2 HOU (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -108, Underdog Moneyline: -108)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!