Brewers vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for May 6

Odds updated as of 5:15 a.m.

The MLB schedule on Tuesday includes the Milwaukee Brewers facing the Houston Astros.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's everything you need to know.

Brewers vs Astros Game Info

• Milwaukee Brewers (18-18) vs. Houston Astros (17-17)
• Date: Tuesday, May 6, 2025
• Time: 7:40 p.m. ET
• Venue: American Family Field -- Milwaukee, Wisconsin
• Coverage: FDSWI and SCHN

Brewers vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIL: (-108) | HOU: (-108)
• Spread: MIL: +1.5 (-192) | HOU: -1.5 (+158)
• Total: 8 -- Over: (-110) | Under: (-110)

Brewers vs Astros Probable Starting Pitchers

Probable Pitchers: Chad Patrick (Brewers) - 1-3, 2.87 ERA vs Hayden Wesneski (Astros) - 1-2, 3.86 ERA

The probable pitchers are Chad Patrick (1-3) for the Brewers and Hayden Wesneski (1-2) for the Astros. Patrick's team is 4-2-0 against the spread in his starts this season. Patrick's team has won 50% of his starts when they are favored on the moneyline (2-2). When Wesneski starts, the Astros have gone 3-2-0 against the spread. The Astros have been the moneyline underdog in three of Wesneski's starts this season, and they went 1-2 in those matchups.

Brewers vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Brewers win (50.4%)

Brewers vs Astros Moneyline

• Looking at the moneyline for Brewers-Astros, Milwaukee is the favorite at -108, and Houston is -108 playing on the road.

Brewers vs Astros Spread

Brewers vs Astros Over/Under

• A combined run total of 8 has been set for Brewers-Astros on May 6, with the over at -110 and the under at -110.

Bet on Milwaukee Brewers vs. Houston Astros on FanDuel today!

Brewers vs Astros Betting Trends

• The Brewers have been favorites in 18 games this season and have come away with the win 13 times (72.2%) in those contests.
• This season Milwaukee has been victorious 14 times in 19 chances when named as a favorite of at least -108 on the moneyline.
• The Brewers and their opponents have gone over the total this season in 15 of their 36 opportunities.
• The Brewers are 21-15-0 against the spread in their 36 games that had a posted line this season.
• The Astros have been the underdog on the moneyline nine total times this season. They've finished 5-4 in those games.
• When it has played as a moneyline underdog with odds of -108 or longer, Houston has a 5-4 record (winning 55.6% of its games).
• The Astros have played in 34 games with a set over/under, and have combined with opponents to go over the total 15 times (15-17-2).
• The Astros have an 18-16-0 record against the spread this season (covering 52.9% of the time).

Brewers Player Leaders

• Jackson Chourio has 39 hits, which is tops among Milwaukee hitters this season, while batting .255 with 19 extra-base hits. He has an on-base percentage of .268 and a slugging percentage of .464.
• Among all qualified hitters in the majors, he is 72nd in batting average, 142nd in on-base percentage, and 47th in slugging.
• Chourio hopes to build on a three-game hitting streak in this matchup. In his last five games he is hitting .150 with a double.
• Brice Turang has an OPS of .772, fueled by an OBP of .372 and a team-best slugging percentage of .400 this season. He's batting .315.
• His batting average is 11th among qualified players, his on-base percentage 32nd, and his slugging percentage 87th.
• William Contreras is batting .248 with a .339 slugging percentage and 19 RBI this year.
• Contreras brings a two-game hitting streak into this game. In his last five games he is hitting .176 with two walks and an RBI.
• Christian Yelich is batting .210 with a .317 OBP and 25 RBI for Milwaukee this season.
• Yelich enters this matchup on a two-game hitting streak. During his last five outings he is hitting .100 with a home run, a walk and two RBI.

Astros Player Leaders

• Jeremy Pena has put up a team-best slugging percentage (.414) and leads the Astros in hits (36). He's batting .281 and with an on-base percentage of .345.
• He is 39th in batting average, 60th in on-base percentage and 75th in slugging percentage among all qualified batters in the majors.
• Pena hopes to build on a nine-game hitting streak in this matchup. During his last 10 games he is hitting .341 with two doubles, a home run, two walks and four RBI.
• Isaac Paredes has a .357 OBP to pace his team. He has a batting average of .258 while slugging .395.
• Including all qualified hitters, his batting average puts him 68th, his on-base percentage is 47th, and he is 95th in slugging.
• Jose Altuve is hitting .259 with four doubles, four home runs and nine walks.
• Jake Meyers has five doubles, a triple, two home runs and eight walks while batting .301.

Brewers vs Astros Head to Head

• 5/5/2025: 5-1 MIL (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 5/19/2024: 9-4 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 5/18/2024: 4-2 MIL (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 5/17/2024: 5-4 HOU (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/24/2023: 4-0 MIL (Favorite: Brewers, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/23/2023: 6-0 MIL (Favorite: Astros, Spread: -1.5, Total: 9.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/22/2023: 12-2 HOU (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -108, Underdog Moneyline: -108)

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