Best College Football Games Week 5: Predictions, Odds, Picks, Best Bets

There are 16 games on the college football schedule in Week 5 that feature a ranked squad. That includes the No. 5 Ohio State Buckeyes versus the No. 14 Iowa Hawkeyes.

Here is the betting info to dissect before Week 5 in college football.

For additional insights, check out the latest college football betting picks from FanDuel Research's staff of writers.

SMU vs. Boston College

• Matchup: Boston College Eagles at No. 21 SMU Mustangs
• Projected Favorite: SMU (91.98% win probability)
• Spread: SMU (-21.5)
• Total: 55.5
• Time: 12 p.m. ET
• Date: Oct. 3
• TV Channel: The CW

Bet on SMU vs. Boston College with FanDuel Sportsbook.

Houston vs. UCF

• Matchup: UCF Knights at No. 20 Houston Cougars
• Projected Favorite: Houston (73.72% win probability)
• Spread: Houston (-10.5)
• Total: 50.5
• Time: 12 p.m. ET
• Date: Oct. 3
• TV Channel: ESPN2

Bet on Houston vs. UCF with FanDuel Sportsbook.

North Carolina vs. Notre Dame

• Matchup: No. 3 Notre Dame Fighting Irish at North Carolina Tar Heels
• Projected Favorite: Notre Dame (92.15% win probability)
• Spread: Notre Dame (-21.5)
• Total: 46.5
• Time: 12 p.m. ET
• Date: Oct. 3
• TV Channel: ESPN

Bet on North Carolina vs. Notre Dame with FanDuel Sportsbook.

Mississippi State vs. Alabama

• Matchup: No. 7 Alabama Crimson Tide at No. 16 Mississippi State Bulldogs
• Projected Favorite: Alabama (65.61% win probability)
• Spread: Alabama (-4.5)
• Total: 62.5
• Time: 12 p.m. ET
• Date: Oct. 3
• TV Channel: ABC

Bet on Mississippi State vs. Alabama with FanDuel Sportsbook.

Georgia vs. Vanderbilt

• Matchup: Vanderbilt Commodores at No. 2 Georgia Bulldogs
• Projected Favorite: Georgia (87.47% win probability)
• Spread: Georgia (-26.5)
• Total: 49.5
• Time: 12:45 p.m. ET
• Date: Oct. 3
• TV Channel: SEC Network

Bet on Georgia vs. Vanderbilt with FanDuel Sportsbook.

Tennessee vs. Auburn

• Matchup: Auburn Tigers at No. 17 Tennessee Volunteers
• Projected Favorite: Tennessee (71.58% win probability)
• Spread: Tennessee (-6.5)
• Total: 54.5
• Time: 3:30 p.m. ET
• Date: Oct. 3
• TV Channel: ESPN

Bet on Tennessee vs. Auburn with FanDuel Sportsbook.

Iowa vs. Ohio State

• Matchup: No. 5 Ohio State Buckeyes at No. 14 Iowa Hawkeyes
• Projected Favorite: Ohio State (69.98% win probability)
• Spread: Ohio State (-14.5)
• Total: 46.5
• Time: 3:30 p.m. ET
• Date: Oct. 3
• TV Channel: CBS

Bet on Iowa vs. Ohio State with FanDuel Sportsbook.

Missouri vs. Florida

• Matchup: No. 8 Florida Gators at No. 25 Missouri Tigers
• Projected Favorite: Missouri (52.90% win probability)
• Spread: Florida (-4.5)
• Total: 57.5
• Time: 3:30 p.m. ET
• Date: Oct. 3
• TV Channel: ABC

Bet on Missouri vs. Florida with FanDuel Sportsbook.

South Carolina vs. Kentucky

• Matchup: No. 24 Kentucky Wildcats at South Carolina Gamecocks
• Projected Favorite: South Carolina (59.55% win probability)
• Spread: South Carolina (-2.5)
• Total: 52.5
• Time: 4:15 p.m. ET
• Date: Oct. 3
• TV Channel: SEC Network

Bet on South Carolina vs. Kentucky with FanDuel Sportsbook.

TCU vs. BYU

• Matchup: No. 10 BYU Cougars at TCU Horned Frogs
• Projected Favorite: BYU (70.78% win probability)
• Spread: BYU (-5.5)
• Total: 48.5
• Time: 7 p.m. ET
• Date: Oct. 3
• TV Channel: ESPN

Bet on TCU vs. BYU with FanDuel Sportsbook.

Boise State vs. Utah State

• Matchup: Utah State Aggies at No. 22 Boise State Broncos
• Projected Favorite: Boise State (86.78% win probability)
• Spread: Boise State (-19.5)
• Total: 51.5
• Time: 7:30 p.m. ET
• Date: Oct. 3
• TV Channel: CBS Sports Network

Bet on Boise State vs. Utah State with FanDuel Sportsbook.

USC vs. Washington

• Matchup: Washington Huskies at No. 18 USC Trojans
• Projected Favorite: USC (78.92% win probability)
• Spread: USC (-7.5)
• Total: 57.5
• Time: 7:30 p.m. ET
• Date: Oct. 3
• TV Channel: NBC

Bet on USC vs. Washington with FanDuel Sportsbook.

Colorado vs. Texas Tech

• Matchup: No. 12 Texas Tech Red Raiders at Colorado Buffaloes
• Projected Favorite: Texas Tech (93.15% win probability)
• Spread: Texas Tech (-13.5)
• Total: 50.5
• Time: 7:30 p.m. ET
• Date: Oct. 3
• TV Channel: FOX

Bet on Colorado vs. Texas Tech with FanDuel Sportsbook.

Clemson vs. Miami (FL)

• Matchup: No. 4 Miami Hurricanes at Clemson Tigers
• Projected Favorite: Miami (FL) (85.78% win probability)
• Spread: Miami (FL) (-15.5)
• Total: 48.5
• Time: 7:44 p.m. ET
• Date: Oct. 3
• TV Channel: ABC

Bet on Clemson vs. Miami (FL) with FanDuel Sportsbook.

LSU vs. McNeese

• Matchup: McNeese Cowboys at No. 11 LSU Tigers
• Projected Favorite: LSU
• Spread: LSU (-54.5)
• Total: 62.5
• Time: 7:55 p.m. ET
• Date: Oct. 3
• TV Channel: SEC Network

Bet on LSU vs. McNeese with FanDuel Sportsbook.

Rutgers vs. Indiana

• Matchup: No. 6 Indiana Hoosiers at Rutgers Scarlet Knights
• Projected Favorite: Indiana (95.78% win probability)
• Spread: Indiana (-24.5)
• Total: 56.5
• Time: 8 p.m. ET
• Date: Oct. 3
• TV Channel: BTN

Bet on Rutgers vs. Indiana with FanDuel Sportsbook.

Matchup favorites and win projections are provided by numberFire.

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