Miami (FL) vs Clemson Prediction, Odds, Picks, Best Bets for Week 5 2026

The Miami Hurricanes are among the college football squads in action on Saturday, versus the Clemson Tigers.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA football odds and spreads you need to know.

Miami (FL) vs Clemson Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Miami (FL): (-1000) | Clemson: (+640)
• Spread: Miami (FL): -16.5 (-115) | Clemson: +16.5 (-105)
• Total: 47.5 -- Over: (-118) | Under: (-104)

Miami (FL) vs Clemson Betting Trends

• Miami (FL)'s record against the spread is 3-1-0.
• This season, Miami (FL) is 3-1 as 16.5-point or better favorites.
• Out of four Miami (FL) games so far this season, three have gone over the total.
• Clemson has posted two wins against the spread this season.
• A pair of Clemson four games in 2026 have hit the over.

Miami (FL) vs Clemson Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Hurricanes win (86.4%)

Miami (FL) vs Clemson Point Spread

Miami (FL) is favored by 16.5 points over Clemson. Miami (FL) is -115 to cover the spread, with Clemson being -105.

Miami (FL) vs Clemson Over/Under

A combined point total of 47.5 has been set for Miami (FL)-Clemson on Oct. 3, with the over at -118 and the under at -104.

Miami (FL) vs Clemson Moneyline

Looking at the moneyline for Miami (FL)-Clemson, Miami (FL) is the favorite at -1000, and Clemson is +640.

Miami (FL) vs. Clemson Points Insights

Miami (FL) vs. Clemson Game Info

• Game day: Saturday, October 3, 2026
• Game time: 7:30 p.m. ET
• TV channel: ABC
• Location: Clemson, South Carolina
• Stadium: Memorial Stadium (Clemson, SC)

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Check out even more in-depth Miami (FL) vs. Clemson analysis on FanDuel Research.