South Carolina vs Kentucky Prediction, Odds, Picks, Best Bets for Week 5 2026

College football's Saturday schedule includes the South Carolina Gamecocks taking on the Kentucky Wildcats.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NCAA football betting insights.

South Carolina vs Kentucky Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: South Carolina: (-142) | Kentucky: (+118)
• Spread: South Carolina: -2.5 (-120) | Kentucky: +2.5 (-102)
• Total: 53.5 -- Over: (-112) | Under: (-108)

South Carolina vs Kentucky Betting Trends

• South Carolina has posted one win against the spread this season.
• As a 2.5-point or greater favorite, South Carolina has one win ATS (1-2) this season.
• There have been three South Carolina games (of four) that hit the over this year.
• Kentucky has beaten the spread three times in four games.
• As a 2.5-point underdog or more, Kentucky has one win ATS (1-1) this year.
• Kentucky has played four games this year, and three of them have gone over the total.

South Carolina vs Kentucky Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Gamecocks win (59.7%)

South Carolina vs Kentucky Point Spread

South Carolina is favored by 2.5 points (-120 to cover) in this matchup. Kentucky, the underdog, is -102.

South Carolina vs Kentucky Over/Under

An over/under of 53.5 has been set for South Carolina-Kentucky on Oct. 3, with the over being -112 and the under -108.

South Carolina vs Kentucky Moneyline

South Carolina is a -142 favorite on the moneyline, while Kentucky is a +118 underdog.

South Carolina vs. Kentucky Points Insights

South Carolina vs. Kentucky Game Info

• Game day: Saturday, October 3, 2026
• Game time: 4:15 p.m. ET
• TV channel: SEC Network
• Location: Columbia, South Carolina
• Stadium: Williams-Brice Stadium

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Check out even more in-depth South Carolina vs. Kentucky analysis on FanDuel Research.