South Carolina vs Kentucky Prediction, Odds, Picks, Best Bets for Week 5 2026

In college football action on Saturday, the South Carolina Gamecocks take on the Kentucky Wildcats.

We've got you covered, in terms of the vital info regarding NCAA football betting lines, before you make your wager on FanDuel Sportsbook.

South Carolina vs Kentucky Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: South Carolina: (-138) | Kentucky: (+115)
• Spread: South Carolina: -2.5 (-115) | Kentucky: +2.5 (-105)
• Total: 52.5 -- Over: (-115) | Under: (-105)

South Carolina vs Kentucky Betting Trends

• South Carolina hasn won once against the spread this season.
• As a 2.5-point or greater favorite, South Carolina has one win ATS (1-2) this season.
• There have been three South Carolina games (of four) that hit the over this year.
• Against the spread, Kentucky is 3-1-0 this year.
• Kentucky has one win ATS (1-1) as a 2.5-point underdog or greater this season.
• Of four Kentucky games so far this year, three have gone over the total.

South Carolina vs Kentucky Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Gamecocks win (59.6%)

South Carolina vs Kentucky Point Spread

South Carolina is a 2.5-point favorite against Kentucky. South Carolina is -115 to cover the spread, and Kentucky is -105.

South Carolina vs Kentucky Over/Under

South Carolina versus Kentucky, on Oct. 3, has an over/under of 52.5, with the over being -115 and the under -105.

South Carolina vs Kentucky Moneyline

South Carolina is the favorite, -138 on the moneyline, while Kentucky is a +115 underdog.

South Carolina vs. Kentucky Points Insights

South Carolina vs. Kentucky Game Info

• Game day: Saturday, October 3, 2026
• Game time: 4:15 p.m. ET
• TV channel: SEC Network
• Location: Columbia, South Carolina
• Stadium: Williams-Brice Stadium

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Check out even more in-depth South Carolina vs. Kentucky analysis on FanDuel Research.