Florida vs Missouri Prediction, Odds, Picks, Best Bets for Week 5 2026

The Florida Gators versus the Missouri Tigers is on the college football schedule for Saturday.

Before you make your wager on FanDuel Sportsbook, we've got you covered, in terms of the vital info about today's NCAA football betting odds.

Florida vs Missouri Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Florida: (-210) | Missouri: (+172)
• Spread: Florida: -4.5 (-115) | Missouri: +4.5 (-105)
• Total: 56.5 -- Over: (-115) | Under: (-105)

Florida vs Missouri Betting Trends

• Florida is 3-1-0 against the spread this year.
• As a 4.5-point or greater favorite, Florida has one win ATS (1-1) this season.
• This year, three of Florida's four games have gone over the point total.
• Missouri has but one win versus the spread this year.
• Missouri has played two games (out of four) which finished over the total this season.

Florida vs Missouri Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Gators win (50.4%)

Florida vs Missouri Point Spread

Missouri is a 4.5-point underdog against Florida. Missouri is -105 to cover the spread, and Florida is -115.

Florida vs Missouri Over/Under

The Florida-Missouri game on Oct. 3 has been given an over/under of 56.5 points. The over is -115 and the under is -105.

Florida vs Missouri Moneyline

Missouri is the underdog, +172 on the moneyline, while Florida is a -210 favorite.

Florida vs. Missouri Points Insights

Florida vs. Missouri Game Info

• Game day: Saturday, October 3, 2026
• Game time: 3:30 p.m. ET
• TV channel: ABC
• Location: Columbia, Missouri
• Stadium: Memorial Stadium/Faurot Field

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Check out even more in-depth Florida vs. Missouri analysis on FanDuel Research.