USC vs Washington Prediction, Odds, Picks, Best Bets for Week 5 2026

In college football action on Saturday, the USC Trojans take on the Washington Huskies.

Get the latest NCAA football odds ahead of this game on FanDuel Sportsbook.

USC vs Washington Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: USC: (-375) | Washington: (+290)
• Spread: USC: -9.5 (-115) | Washington: +9.5 (-105)
• Total: 58.5 -- Over: (-115) | Under: (-105)

USC vs Washington Betting Trends

• USC hasn won once against the spread this season.
• USC has won once ATS (1-3) as a 9.5-point or higher favorite this year.
• Out of five USC games so far this year, four have hit the over.
• Washington has no wins against the spread this year.
• Two Washington games (of four) have hit the over this season.

USC vs Washington Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Trojans win (79.8%)

USC vs Washington Point Spread

Washington is listed as an underdog by 9.5 points (-105 odds), and USC, the favorite, is -115 to cover.

USC vs Washington Over/Under

The over/under for the USC versus Washington game on Oct. 3 has been set at 58.5, with -115 odds on the over and -105 odds on the under.

USC vs Washington Moneyline

USC is a -375 favorite on the moneyline, while Washington is a +290 underdog.

USC vs. Washington Points Insights

USC vs. Washington Game Info

• Game day: Saturday, October 3, 2026
• Game time: 7:30 p.m. ET
• TV channel: NBC
• Location: Los Angeles, California
• Stadium: Los Angeles Memorial Coliseum

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Check out even more in-depth USC vs. Washington analysis on FanDuel Research.