USC vs Washington Prediction, Odds, Picks, Best Bets for Week 5 2026

College football's Saturday slate includes the USC Trojans facing the Washington Huskies.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NCAA football betting insights.

USC vs Washington Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: USC: (-319) | Washington: (+255)
• Spread: USC: -7.5 (-110) | Washington: +7.5 (-110)
• Total: 57.5 -- Over: (-110) | Under: (-110)

USC vs Washington Betting Trends

• USC has one win against the spread this year.
• USC owns one win ATS (1-3) as a 7.5-point favorite or greater this year.
• USC has played five games this season, and four of them have hit the over.
• Washington is winless against the spread this season.
• A pair of Washington four games in 2026 have gone over the point total.

USC vs Washington Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Trojans win (78.9%)

USC vs Washington Point Spread

Washington is the underdog by 7.5 points against USC. Washington is -110 to cover the spread, and USC is -110.

USC vs Washington Over/Under

A combined point total of 57.5 has been set for USC-Washington on Oct. 3, with the over at -110 and the under at -110.

USC vs Washington Moneyline

The moneyline numbers for USC vs. Washington reveal USC as the favorite (-319) and Washington as the underdog (+255).

USC vs. Washington Points Insights

USC vs. Washington Game Info

• Game day: Saturday, October 3, 2026
• Game time: 7:30 p.m. ET
• TV channel: NBC
• Location: Los Angeles, California
• Stadium: Los Angeles Memorial Coliseum

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Check out even more in-depth USC vs. Washington analysis on FanDuel Research.