Astros vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for June 11

Odds updated as of 7:11 p.m.

The MLB schedule on Wednesday includes the Houston Astros facing the Chicago White Sox.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important info regarding this game.

Astros vs White Sox Game Info

• Houston Astros (36-30) vs. Chicago White Sox (23-44)
• Date: Wednesday, June 11, 2025
• Time: 8:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and CHSN

Astros vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-172) | CHW: (+144)
• Spread: HOU: -1.5 (+125) | CHW: +1.5 (-150)
• Total: 8 -- Over: (-118) | Under: (-104)

Astros vs White Sox Probable Starting Pitchers

Probable Pitchers: Ryan Gusto (Astros) - 3-3, 4.78 ERA vs Sean Burke (White Sox) - 3-6, 4.03 ERA

The probable pitchers are Ryan Gusto (3-3) for the Astros and Sean Burke (3-6) for the White Sox. Gusto's team is 3-5-0 against the spread this season in his starts. When Gusto starts a game and his team is the favorite on the moneyline, they have a record of 3-5. The White Sox are 8-3-0 against the spread when Burke starts. The White Sox have a 6-5 record in Burke's 11 starts this season when they were the underdog on the moneyline.

Astros vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (65.5%)

Astros vs White Sox Moneyline

• Chicago is a +144 underdog on the moneyline, while Houston is a -172 favorite at home.

Astros vs White Sox Spread

• The Astros are 1.5-run home favorites on the runline against the White Sox. The Astros are +125 to cover, and the White Sox are -150.

Astros vs White Sox Over/Under

• Astros versus White Sox, on June 11, has an over/under of 8, with the over being -118 and the under -104.

Bet on Houston Astros vs. Chicago White Sox on FanDuel today!

Astros vs White Sox Betting Trends

• The Astros have won in 24, or 54.5%, of the 44 contests they have been named as odds-on favorites in this year.
• This year Houston has won three of six games when listed as at least -172 on the moneyline.
• The Astros and their opponents have gone over in 25 of their 65 games with a total set by sportsbooks this season.
• The Astros are 34-31-0 against the spread in their 65 games that had a posted line this season.
• The White Sox have been the moneyline underdog 63 total times this season. They've gone 21-42 in those games.
• Chicago is 10-29 (winning only 25.6% of its games) when it has played as a moneyline underdog of +144 or longer.
• The White Sox have played in 64 games with an over/under set, and have combined with their opponents to go over the total 30 times (30-31-3).
• The White Sox have covered 56.2% of their games this season, going 36-28-0 ATS.

Astros Player Leaders

• Jeremy Pena has 81 hits and an OBP of .375 to go with a slugging percentage of .484. All three of those stats are best among Houston hitters this season. He has a .319 batting average, as well.
• Among all qualifying hitters in the majors, he is eighth in batting average, 23rd in on-base percentage, and 34th in slugging.
• Isaac Paredes is hitting .247 with seven doubles, a triple, 14 home runs and 35 walks, while slugging .457 with an on-base percentage of .346.
• His batting average ranks 102nd among qualified players, his on-base percentage 54th, and his slugging percentage 53rd.
• Jose Altuve is batting .266 with a .399 slugging percentage and 24 RBI this year.
• Jake Meyers has three home runs, 16 RBI and a batting average of .300 this season.
• Meyers brings a four-game hitting streak into this game. During his last five outings he is batting .389 with a double and three walks.

White Sox Player Leaders

• Miguel Vargas has accumulated 54 hits with a .314 on-base percentage, leading the White Sox in both categories. He's batting .233 and slugging .414.
• Including all qualifying hitters, he is 126th in batting average, while his on-base percentage ranks 108th and he is 92nd in slugging.
• Chase Meidroth is hitting .293 with five doubles, two home runs and 23 walks. He's slugging .363 with an on-base percentage of .383.
• Andrew Benintendi is batting .241 with six doubles, a triple, six home runs and 15 walks.
• Luis Robert is hitting .184 with seven doubles, six home runs and 25 walks.

Astros vs White Sox Head to Head

• 6/10/2025: 4-2 CHW (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 5/4/2025: 5-4 CHW (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 5/3/2025: 8-3 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 5/2/2025: 7-3 CHW (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 8/18/2024: 2-0 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -375, Underdog Moneyline: +300)
• 8/17/2024: 6-1 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -375, Underdog Moneyline: +300)
• 8/16/2024: 5-4 CHW (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -275, Underdog Moneyline: +225)
• 6/20/2024: 5-3 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -176, Underdog Moneyline: +148)
• 6/19/2024: 4-1 HOU (Favorite: Astros, Spread: -1.5, Total: 7, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/18/2024: 2-0 CHW (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -178, Underdog Moneyline: +150)

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