Astros vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for May 2

Odds updated as of 7:11 p.m.

The Houston Astros are among the MLB teams busy on Friday, versus the Chicago White Sox.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Astros vs White Sox Game Info

• Houston Astros (16-14) vs. Chicago White Sox (8-23)
• Date: Friday, May 2, 2025
• Time: 7:40 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and SCHN

Astros vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-240) | CHW: (+198)
• Spread: HOU: -1.5 (-134) | CHW: +1.5 (+112)
• Total: 7.5 -- Over: (-118) | Under: (-104)

Astros vs White Sox Probable Starting Pitchers

Probable Pitchers: Framber Valdez (Astros) - 1-3, 4.00 ERA vs Jonathan Cannon (White Sox) - 1-3, 4.50 ERA

This contest's pitching matchup is set, as the Astros will send Framber Valdez (1-3) to the mound, while Jonathan Cannon (1-3) will get the nod for the White Sox. When Valdez starts, his team is 3-3-0 against the spread this season. Valdez's team has been victorious in 20% of the games he's started as the moneyline favorite with a record of 1-4. The White Sox have a 1-4-0 record against the spread in Cannon's starts. The White Sox were named the moneyline underdog for five Cannon starts this season -- they lost every game.

Astros vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (65.3%)

Astros vs White Sox Moneyline

• Houston is the favorite, -240 on the moneyline, while Chicago is a +198 underdog despite being at home.

Astros vs White Sox Spread

• The Astros are at the White Sox and are favored by 1.5 runs on the spread. The Astros are -134 to cover the runline, with the White Sox being +112.

Astros vs White Sox Over/Under

• A total of 7.5 runs has been set for the Astros-White Sox contest on May 2, with the over available at -118 and the under at -104.

Bet on Houston Astros vs. Chicago White Sox on FanDuel today!

Astros vs White Sox Betting Trends

• The Astros have been victorious in 11, or 52.4%, of the 21 contests they have been chosen as favorites in this season.
• Oddsmakers have given Houston the best odds of winning it has seen this season, with a -240 moneyline listed for this contest.
• The Astros and their opponents have gone over in 12 of their 30 games with a total set by sportsbooks this season.
• The Astros are 17-13-0 against the spread in their 30 games with a line set by sportsbooks this season.
• The White Sox have won eight of the 31 games they were listed as the moneyline underdog this season (25.8%).
• Chicago is 1-7 (winning just 12.5% of its games) when it has played as a moneyline underdog of +198 or longer.
• The White Sox have combined with opponents to go over the total 14 times this season for a 14-15-2 record against the over/under.
• The White Sox have collected a 16-15-0 record against the spread this season (covering 51.6% of the time).

Astros Player Leaders

• Jeremy Pena leads Houston with 31 hits, batting .282 this season with nine extra-base hits. He has an on-base percentage of .355 and a slugging percentage of .436.
• Among qualified hitters in baseball, his batting average ranks 39th, his on-base percentage ranks 49th, and he is 62nd in slugging.
• Pena will look for his sixth straight game with a hit in this matchup. During his last five outings he is batting .450 with two doubles, a home run, two walks and four RBI.
• Isaac Paredes leads Houston with an OBP of .362 this season while batting .252 with 17 walks and 14 runs scored. He's slugging .405.
• He ranks 76th in batting average, 42nd in on-base percentage and 89th in slugging among qualified hitters.
• Paredes brings a three-game streak with at least one hit into this matchup. During his last five outings he is batting .294 with a double, a triple, five walks and an RBI.
• Jose Altuve has an OPS of .725, fueled by an OBP of .323 and a team-best slugging percentage of .402 this season.
• Yordan Alvarez has three home runs, 18 RBI and a batting average of .219 this season.
• Alvarez has hit safely in three straight games. During his last five outings he is hitting .211 with a double, a home run, two walks and five RBI.

White Sox Player Leaders

• Luis Robert has three doubles, four home runs and 17 walks while hitting .183. He's slugging .327 with an on-base percentage of .295.
• Including all the qualifying hitters in the majors, his batting average ranks 155th, his on-base percentage ranks 116th, and he is 136th in slugging.
• Robert hopes to build on a six-game hitting streak in this matchup. During his last 10 outings he is hitting .231 with two doubles, two home runs, five walks and seven RBI.
• Andrew Benintendi is batting .231 with five home runs and eight walks. He's slugging .423 with an on-base percentage of .310.
• Miguel Vargas has racked up an on-base percentage of .311, a team-best for the White Sox.
• Lenyn Sosa has racked up 29 hits while slugging .361. Both are team-highs.

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