Astros vs Rockies Prediction, Odds, Moneyline, Spread & Over/Under for April 16

Odds updated as of 8:11 p.m.

In MLB action on Thursday, the Houston Astros take on the Colorado Rockies.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Astros vs Rockies Game Info

• Houston Astros (8-11) vs. Colorado Rockies (6-12)
• Date: Thursday, April 16, 2026
• Time: 8:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and Rockies.TV

Astros vs Rockies Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-172) | COL: (+144)
• Spread: HOU: -1.5 (+118) | COL: +1.5 (-142)
• Total: 8.5 -- Over: (-114) | Under: (-106)

Astros vs Rockies Probable Starting Pitchers

Probable Pitchers: Ryan Weiss (Astros) - 0-2, 7.36 ERA vs Juan Mejia (Rockies) - 0-2, 5.40 ERA

This contest's pitching matchup is set, as the Astros will send Ryan Weiss (0-2) to the mound, while Juan Mejia (0-2) will get the nod for the Rockies. Weiss did not pitch as the moneyline favorite last season. Mejia and his team were underdogs on the moneyline each game he pitched a season ago.

Astros vs Rockies Moneyline

• The moneyline numbers for Astros vs. Rockies reveal Houston as the favorite (-172) and Colorado as the underdog (+144) on the road.

Astros vs Rockies Spread

• The Rockies are +1.5 on the run line against the Astros. The Rockies are -142 to cover, and the Astros are +118.

Astros vs Rockies Over/Under

• The over/under for the Astros versus Rockies game on April 16 has been set at 8.5, with -114 odds on the over and -106 odds on the under.

Bet on Houston Astros vs. Colorado Rockies on FanDuel today!

Astros vs Rockies Betting Trends

• The Astros have been victorious in five, or 45.5%, of the 11 contests they have been chosen as favorites in this season.
• Houston has a record of 2-3 when favored by -172 or more this year.
• The Astros and their opponents have gone over in 13 of their 19 games with a total set by sportsbooks this season.
• In 19 games with a line this season, the Astros have a mark of 8-11-0 against the spread.
• The Rockies are 6-12 in games they were the underdog on the moneyline (winning 33.3% of those games).
• Colorado is 2-11 (winning only 15.4% of its games) when playing as a moneyline underdog of +144 or longer.
• The Rockies have played in 18 games with an over/under set, and have combined with opponents to go over the total seven times (7-11-0).
• The Rockies have put together an 11-7-0 record against the spread this season.

Astros Player Leaders

• Yordan Alvarez leads Houston in OBP (.488), slugging percentage (.762) and total hits (21) this season. He has a .333 batting average.
• Among qualified batters in the majors, his batting average ranks seventh, his on-base percentage ranks first, and he is first in slugging.
• Alvarez hopes to build on a two-game hitting streak in this matchup. In his last five games he is hitting .316 with three doubles, two home runs, three walks and four RBIs.
• Christian Walker is hitting .303 with six doubles, four home runs and nine walks. He's slugging .576 with an on-base percentage of .382.
• Among all qualifying hitters, he ranks 28th in batting average, 32nd in on-base percentage and 15th in slugging percentage.
• Cam Smith is batting .288 with a .500 slugging percentage and 10 RBI this year.
• Smith brings a three-game hitting streak into this matchup. In his last five games he is batting .389 with three doubles, a walk and four RBIs.
• Jose Altuve has two home runs, six RBI and a batting average of .288 this season.

Rockies Player Leaders

• T.J. Rumfield has accumulated an on-base percentage of .343 and a slugging percentage of .433. Both lead the Rockies. He's batting .283.
• He is 49th in batting average, 78th in on-base percentage and 70th in slugging percentage among all qualified hitters in the big leagues.
• Mickey Moniak is batting .250 with a double, five home runs and a walk. He's slugging .650 with an on-base percentage of .262.
• Troy Johnston is hitting .298 with three doubles, two home runs and four walks.
• Hunter Goodman has racked up 15 hits to pace his team.

Astros vs Rockies Head to Head

• 4/15/2026: 3-1 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -196, Underdog Moneyline: +164)
• 4/14/2026: 7-6 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 4/8/2026: 9-1 COL (Favorite: Astros, Spread: -1.5, Total: 11, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/7/2026: 5-1 COL (Favorite: Astros, Spread: -1.5, Total: 11, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 4/6/2026: 9-7 COL (Favorite: Astros, Spread: -1.5, Total: 10.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 8/28/2025: 4-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -250, Underdog Moneyline: +205)
• 8/27/2025: 4-0 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -275, Underdog Moneyline: +225)
• 8/26/2025: 6-1 COL (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -375, Underdog Moneyline: +300)
• 7/3/2025: 7-6 COL (Favorite: Astros, Spread: -1.5, Total: 11, Favorite Moneyline: -188, Underdog Moneyline: +158)
• 7/2/2025: 5-3 HOU (Favorite: Astros, Spread: -1.5, Total: 11, Favorite Moneyline: -260, Underdog Moneyline: +215)

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