Astros vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for July 8

Odds updated as of 7:11 p.m.

MLB action on Tuesday includes the Houston Astros taking on the Cleveland Guardians.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's everything you need to know.

Astros vs Guardians Game Info

• Houston Astros (55-36) vs. Cleveland Guardians (41-48)
• Date: Tuesday, July 8, 2025
• Time: 8:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and CLEG

Astros vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-200) | CLE: (+168)
• Spread: HOU: -1.5 (+104) | CLE: +1.5 (-125)
• Total: 7 -- Over: (-120) | Under: (-102)

Astros vs Guardians Probable Starting Pitchers

Probable Pitchers: Hunter Brown (Astros) - 9-3, 1.82 ERA vs Joey Cantillo (Guardians) - 1-0, 3.41 ERA

The Astros will give the nod to Hunter Brown (9-3, 1.82 ERA), who is eyeing win No. 10 on the season, and the Guardians will turn to Joey Cantillo (1-0, 3.41 ERA). Brown's team is 11-6-0 against the spread this season in his starts. Brown's team is 11-3 this season when he starts and they are the moneyline favorite. Cantillo has started only one game with a set spread, which the Guardians covered. The Guardians were the underdog on the moneyline for one Cantillo start this season -- they lost.

Astros vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (69.3%)

Astros vs Guardians Moneyline

• The Astros vs Guardians moneyline has Houston as a -200 favorite, while Cleveland is a +168 underdog on the road.

Astros vs Guardians Spread

• The Astros are hosting the Guardians and are favored by 1.5 runs on the spread. The Astros are +104 to cover the runline, with the Guardians being -125.

Astros vs Guardians Over/Under

• A combined run total of 7 has been set for Astros-Guardians on July 8, with the over at -120 and the under at -102.

Bet on Houston Astros vs. Cleveland Guardians on FanDuel today!

Astros vs Guardians Betting Trends

• The Astros have been victorious in 37, or 59.7%, of the 62 contests they have been chosen as favorites in this season.
• Houston has a record of 4-1 in contests when sportsbooks favor them by -200 or more on the moneyline.
• The Astros' games have gone over the total in 37 of their 90 opportunities.
• In 90 games with a line this season, the Astros have a mark of 47-43-0 against the spread.
• The Guardians have won 22 of the 57 games they were listed as the moneyline underdog this season (38.6%).
• Cleveland has not won a game when entering as a moneyline underdog with odds of +168 or longer in three chances.
• The Guardians have played in 87 games with an over/under set, and have combined with their opponents to go over the total 37 times (37-47-3).
• The Guardians have covered 49.4% of their games this season, going 43-44-0 against the spread.

Astros Player Leaders

• Isaac Paredes is hitting .257 with 12 doubles, a triple, 19 home runs and 44 walks. He has an on-base percentage of .355 while slugging .474.
• Among all qualifying hitters in baseball, he is 82nd in batting average, 39th in on-base percentage, and 40th in slugging.
• Paredes will look for his seventh straight game with a hit in this contest. During his last 10 outings he is batting .318 with two doubles, three home runs, two walks and four RBIs.
• Jose Altuve is hitting .268 with 12 doubles, a triple, 16 home runs and 31 walks, while slugging .451 with an on-base percentage of .328.
• Among qualifiers, he is 60th in batting average, 80th in on-base percentage and 59th in slugging percentage.
• Jake Meyers has collected 89 base hits, an OBP of .369 and a slugging percentage of .405 this season.
• Yainer Diaz has been key for Houston with 75 hits, an OBP of .276 plus a slugging percentage of .405.

Guardians Player Leaders

• Jose Ramirez has put up an on-base percentage of .361 and has 97 hits, both team-best figures for the Guardians. He's batting .298 and slugging .495.
• Including all qualifying hitters in MLB, his batting average places him 12th, his on-base percentage is 30th, and he is 24th in slugging.
• Steven Kwan's .415 slugging percentage leads his team. He has a batting average of .297 with an on-base percentage of .356.
• He is currently 13th in batting average, 35th in on-base percentage and 88th in slugging percentage among all qualified batters.
• Carlos Santana is hitting .232 with seven doubles, 10 home runs and 39 walks.
• Angel Martinez is hitting .238 with 13 doubles, a triple, five home runs and eight walks.

Astros vs Guardians Head to Head

• 7/7/2025: 7-5 CLE (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 6/8/2025: 4-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 6/7/2025: 5-3 HOU (Favorite: Astros, Spread: -1.5, Total: 7, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 6/6/2025: 4-2 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/28/2024: 4-3 HOU (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 9/27/2024: 5-2 HOU (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 5/2/2024: 8-2 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 5/1/2024: 3-2 CLE (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 4/30/2024: 10-9 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 8/2/2023: 3-2 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)

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